Results 231 to 240 of about 758,251 (341)

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

open access: yesAdvanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo   +5 more
wiley   +1 more source

Antiviral activity, pharmacokinetics and safety of the second-generation hepatitis B core inhibitor ABI-H2158 in Phase 1b study of patients with HBeAg-positive chronic hepatitis B infection

open access: bronze, 2020
Kosh Agarwal   +15 more
openalex   +1 more source

Metformin‐Based Covalent Organic Frameworks With Excellent Biosafety and High Efficiency against Pathogenic Microorganisms

open access: yesAdvanced Science, EarlyView.
This work presents the first metformin‐based COFs featuring built‐in biosafety and a unique triple‐synergy mechanism. This scalable platform achieves broad‐spectrum eradication of bacteria and viruses, enabling reusable protective membranes with exceptional biocompatibility for advanced biomedical applications and personal protection.
Jia‐Yi Liu   +11 more
wiley   +1 more source

Basal IFNλ2/3 signaling is required for ISG expression and viral control in human intestinal epithelial cells. [PDF]

open access: yesPLoS Pathog
Keser Y   +5 more
europepmc   +1 more source

Serum Bile Acids Are Useful Indicators of Intrahepatic Recurrence After Initial Curative Hepatectomy for Hepatocellular Carcinoma

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim Bile acids accumulation in hepatocytes causes liver damage and contributes to the development of hepatocellular carcinoma. However, the association between serum bile acid levels and postoperative intrahepatic recurrence in hepatocellular carcinoma remains unclear.
Tomoaki Bekki   +9 more
wiley   +1 more source

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