Results 311 to 320 of about 928,338 (389)

An Anti-HIV Drug Is Highly Effective Against SARS-CoV-2 In Vitro and Has Potential Benefit for Long COVID Treatment. [PDF]

Viruses
Khaidarov S, Hejran AB, Moldakaryzova A, Izmailova S, Nurgaliyeva B, Beisenova A, Mustafaeva A, Nurzhanova K, Belova Y, Satbayeva E, Aidarov A, Ossikbayeva S, Kukubassov Y, Amankulov J, Goncharova T, Yeszhan B, Tulman E, Tazhibayeva KN, Sadykova A, Kozhabergenov N, Burashev Y.   +20 more
europepmc   +1 more source

Epidermal Interferon kappa drives cutaneous lupus‐like lesions, photosensitivity and systemic autoimmunity in vivo

Arthritis &Rheumatology, Accepted Article.
Objective Keratinocyte‐derived interferon kappa (IFN‐κ) is chronically overexpressed in human non‐lesional systemic lupus erythematosus (SLE) skin. Recent evidence suggests that epidermal signals instruct the immune system in SLE, but whether epidermal IFN‐κ alone is sufficient to drive lupus phenotypes has not been investigated.
Benjamin Klein, Deborah J. Colesa, Yiqing Gao, Patrick A. O'Brien, Lin Zhang, Lori Lowe, Kelsey E. McNeely, Nguyen Thi Kim Nguyen, Svenja Henning, Mehrnaz Gharaee‐Kermani, Jeffrey B. Hodgin, Jacob W. S. Martens, Johann E. Gudjonsson, Celine C. Berthier, J. Michelle Kahlenberg   +14 more
wiley   +1 more source

Evaluation of the efficacy and mechanisms of azvudine in elderly patients with malignant tumors complicated by COVID-19

Acta Pharmaceutica Sinica B
Ranran Sun, Yihang Song, Zhe Li, Daming Wang, Zujiang Yu   +4 more
doaj   +1 more source

Hepatocellular Carcinoma Recurrence in Patients with Chronic Hepatitis C Infection Treated with Direct-Acting Antivirals: A Systematic Review and Meta-Analysis. [PDF]

Infect Dis Ther
Lindsley K, Burroughs M, Hernandez-Lopez C, Wang Y, Marcinak J, Chiuve SE, Haber BA, Uyei J, Navadeh S, De Marco G, Hill DD.   +10 more
europepmc   +1 more source

Design and Synthesis of Triazole‐Based p‐tert‐Butylcalix[4]Arene Conjugates and Evaluation of Their Antimicrobial, Antibiofilm, and Anti‐Quorum‐Sensing Activities

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Macrocyclic calix[n]arenes have many applications, with diverse structures that can easily be functionalized either on upper or lower rims, mostly to impart solubility and improve biological activities. In this study, triazole‐based p‐tert‐butylcalix[4]arene conjugates (AT10a and AT10b) and their p‐tert‐butylphenol analogs (AT10b and AT11b ...
Alfred Ngenge Tamfu, Selahattin Bozkurt, Ozgur Ceylan   +2 more
wiley   +1 more source

In silico screening and experimental validation identify riboflavin as an RNA-targeted antiviral against SARS-CoV-2. [PDF]

Sci Rep
Jeong CH, Na YJ, Kim TY, Lee SY, Kim J, Ryou S.   +5 more
europepmc   +1 more source

STUDIES ON A NEW ANTIVIRAL ANTIBIOTIC, 9-METHYLSTREPTIMIDONE. I

, 1974
Noriyuki Saito, Fumio Kitame, Mikio Kikuchi, Nakao Ishida   +3 more
openalex   +2 more sources

Synthesis, Characterization, Biological Properties, and Sensor Applications of Novel Thiosemicarbazone Derivatives

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT In this study, novel thiosemicarbazone derivative molecules (5a–j) were synthesized. The characterization of the synthesized molecules was carried out using 1H–, 13C–NMR, FT–IR, and Q–TOF spectroscopic techniques. Then, the inhibitory effect of these compounds was examined for human carbonic anhydrase I and II (hCA I, and II) and ...
Hayreddin Gezegen, Oguz Özbek, Meryem Topal, Hatice Şahin, Ümit M. Koçyiğit   +4 more
wiley   +1 more source

A Pyrido-Quinoxaline Derivative That Downregulates Reticulon 3 Protein Exhibits Potent Antiviral Activity Against Zika Virus. [PDF]

J Med Virol
Plicanti E, Deiana A, Nottoli S, Lottini G, Ibba R, Piras S, Di Marzo C, Vegni S, Lai M, Pistello M, Carta A, Freer G.   +11 more
europepmc   +1 more source