Results 331 to 340 of about 928,338 (389)

Gold nanoparticle-based delivery of Cas13d for targeted RNA virus defense. [PDF]

Mol Ther Nucleic Acids
Alves da Silva NJ, Rodrigues Alves MT, França FA, Guimarães PPG.   +3 more
europepmc   +1 more source

Efficient Extraction of Phenolic Compounds From Cariniana rubra Gardener Ex Miers From the Legal Amazon: Ultrasound‐Assisted Optimization, Chemical Characterization, and Antioxidant Potential

Chemistry &Biodiversity, EarlyView.
ABSTRACT Cariniana rubra, native to the Brazilian Cerrado and the Amazon‐Cerrado ecotone, is traditionally used in folk medicine but remains underexplored. This study optimized extraction yield and bioactive compound content using ultrasound‐assisted extraction (UAE) and Soxhlet extraction.
Aline Biggi Maciel, Elis Ramos de Queiroz Jácome, Naísa Andrade da Silva, Rachel de Moura Nunes Fernandes, Claudia Andrea Lima Cardoso, Elisandra Scapin   +5 more
wiley   +1 more source

Antiviral Activity of Diltiazem HCl Against Pseudorabies Virus Infection In Vitro. [PDF]

Vet Sci
Zuo M, Xiang D, Zhang ZX, Yang X, Duan Y, Li J, Zeng B, Dong L, Wu G, Zhou Y, Tan L, Duan B.   +11 more
europepmc   +1 more source

Piper auritum (Kunth) Fungal Endophytes: A Source of Metabolites to Inhibit the Formation of Advanced Glycation End Products

Chemistry &Biodiversity, EarlyView.
Endophytic fungi of P. auritum were evaluated for their ability to produce inhibitors of formation of advanced glycation end products (AGEs). Neopestalotiopsis sp. H2 and Diaporthe sp. H5 extracts were the most active. So, we performed their chemical profiling by untargeted and phenolics‐targeted metabolomic approaches to identify the potential ...
Lory Sthephany Rochín‐Hernández, José Antonio Guerrero‐Analco, Juan Luis Monribot‐Villanueva, Luis Bernardo Flores‐Cotera   +3 more
wiley   +1 more source

Effects of Baloxavir Marboxil Plus Neuraminidase Inhibitor vs Neuraminidase Inhibitor in High-risk Patients Hospitalized With Severe Influenza: A Post Hoc Analysis of the Flagstone Trial. [PDF]

Open Forum Infect Dis
Yan M, Gu X, Wang Y, Cao B.
europepmc   +1 more source

A Promising Antibacterial Inhibition of Propolis Extracts Against Carbapenem‐Resistant Bacteria Isolated From Clinical Samples

Chemistry &Biodiversity, EarlyView.
ABSTRACT The increasing inadequacy of antibiotics against multidrug‐resistant pathogens is a growing concern. In this study, the antibacterial activity of propolis extracts with different phenolic profiles against carbapenem‐resistant clinical isolates was investigated.
Ülkü Zeynep Esertaş, Neşe Inal, Zehra Can, Sevgi Kolaylı   +3 more
wiley   +1 more source

Hepatitis B reactivation with TNF-α inhibitors: assessing antiviral prophylaxis efficacy - protocol for systematic review and meta-analysis. [PDF]

Syst Rev
Marouf A, Sedra S.
europepmc   +1 more source

Chemical Characterization, Antioxidant, and Anticholinesterase Activities of Libidibia ferrea (Mart. Ex Tul.) L.P.Queiroz and In Silico Studies with the Acetylcholinesterase Enzyme

Chemistry &Biodiversity, EarlyView.
ABSTRACT Libidibia ferrea is used in many parts of Brazil for a variety of conditions, such as inflammation, respiratory disorders, muscle pain, and gastrointestinal problems. This study evaluated the chemistry and antioxidant and acetylcholinesterase (AChE) inhibitory activities of L. ferrea extracts. Hydroethanolic extracts of leaves (ELLF) and bark (
Lucas Soares Frota, Sara Ingrid Caetano Gomes Barbosa, Camila Costa Feitosa, Francisco Flávio da Silva Lopes, Daniel Pereira de Oliveira, Leonardo Soares Freitas, Adriano Lincoln Albuquerque Mattos, Wildson Max Barbosa da Silva, Hamilton Mitsugu Ishiki, Selene Maia de Morais   +9 more
wiley   +1 more source

Exploring Bioactive Metabolites From Fusarium falciforme and Aspergillus terreus Isolated From Protease‐Rich Fruits: Antifungal, Antitrypanosomal, and Enzymatic Inhibitory Activities

Chemistry &Biodiversity, EarlyView.
Metabolites from fungi isolated from protease rich‐fruits displayed antifungal, antitrypanosomal and enzymatic inhibitory activities. ABSTRACT Fungal secondary metabolites display remarkable chemical diversity and biological potential, with applications in agriculture and pharmaceuticals. This study isolated and characterized bioactive metabolites from
Gabriela de Oliveira Almeida, Vitor de Souza Mazucato, Ludmilla Tonani, Marcia Regina von Zeska Kress, Gisele Barbosa, Renata Krogh, Adriano Defini Andricopulo, Leonardo Luiz Gomes Ferreira, Paulo Cezar Vieira   +8 more
wiley   +1 more source

Chemical Composition, Antioxidant, and Antibacterial Activities of Mezilaurus duckei (Lauraceae)

Chemistry &Biodiversity, EarlyView.
ABSTRACT Mezilaurus duckei, a Brazilian endemic tree species found exclusively in the Amazon Rainforest, is primarily exploited for timber in construction. Due to its endangered status, this study aimed to investigate the chemical profile and biological properties of the ethanolic extract and its phases derived from M. duckei leaves. Chemical profiling
Bruna S. Moroto, Valéria S. Gonçalves, David J. Machate, Talita V. Freire, Érica L. Santos, Flávio M. Alves, Ana C. Micheletti, Nídia C. Yoshida   +7 more
wiley   +1 more source