Results 91 to 100 of about 355,010 (330)

Innovative Integration of Layered Carbon Materials in Biopolymer Fibrous Membranes for Sustainable Water Treatment

Advanced Sustainable Systems, EarlyView.
This review explores the progressive design of biopolymer‐based fibrous membranes enhanced with layered carbon materials such as MXene, graphene oxide, and carbon nanotubes. It highlights how their integration significantly boosts water filtration performance, selectivity, and antifouling properties.
Sanaz Khademolqorani, Kinjal J Shah, Mandana Dilamian, Ahmed I. Osman, Esra Altiok, Shohreh Azizi, Ilunga Kamika, Yuxin Yang, Fatma Yalcinkaya, Andre Yvaz, Seyedeh Nooshin Banitaba   +10 more
wiley   +1 more source

Antiviral Activity of 3-Methyleneoxindole [PDF]

Antimicrobial Agents and Chemotherapy, 1974
3-Methyleneoxindole (MO), an oxidation product of the plant auxin indole-3-acetic acid, can selectively inhibit the replication of herpes-, mengo-, polioviruses, and Sindbis virus. The antiviral action of MO, a sulfhydryl binding compound, is neutralized by 2-mercaptoethanol if the latter is added soon after exposure of infected cells to MO.
I. Gordon, I. Gordon, D. Stevenson, D. Stevenson, H. S. Moyed, H. S. Moyed, V. Tuli, V. Tuli   +7 more
openaire   +3 more sources

Drug Repurposing to find Inhibitors of SARS-CoV-2 Main Protease [PDF]

arXiv, 2020
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the strain of coronavirus that causes coronavirus disease 2019 (COVID-19), the respiratory illness responsible for the COVID-19 pandemic. Currently there is no known vaccine or specific antiviral treatment for COVID-19 and so, there is an urgent need for expedite discovery of new ...
arxiv  

Insights into the Dynamics and Binding Mechanisms of the Alkhumra Virus NS2B/NS3 Protease: A Molecular Dynamics Study

Advanced Theory and Simulations, EarlyView.
The ΔRMSF$\Delta {\rm RMSF}$ analysis reveals significant flexibility differences between free NS3 and the NS2B/NS3 complex, with notable deviations in specific regions. Key residues driving NS2B binding are identified, and the protonation state of catalytic serine affects oxyanion hole formation.
Jurica Novak, Shivananda Kandagalla, Ramesh Sistla   +2 more
wiley   +1 more source

Quercetin and quercetin 3-O-glycosides from Bauhinia longifolia (Bong.) Steud. show anti-Mayaro virus activity

Parasites & Vectors, 2014
Background The arthropod-borne Mayaro virus (MAYV) causes ‘Mayaro fever’, a disease of medical significance, primarily affecting individuals in permanent contact with forested areas in tropical South America. Recently, MAYV has attracted attention due to
Alda E dos Santos, Ricardo M Kuster, Kristie A Yamamoto, Tiago S Salles, Renata Campos, Marcelo DF de Meneses, Márcia R Soares, Davis Ferreira   +7 more
doaj   +1 more source

Apoptotic Vesicles Derived from Mesenchymal Stem Cells Ameliorate Hypersensitivity Responses via Inducing CD8+ T Cells Apoptosis with Calcium Overload and Mitochondrial Dysfunction

Advanced Science, EarlyView.
The therapeutic potential of ApoVs derived from stem cells from human exfoliated deciduous teeth (SHED‐ApoVs) in the treatment of CD8+ T cell‐mediated hypersensitivity reactions is noteworthy. SHED‐ApoVs are capable of fusing with the plasma membrane of CD8+ T cells, which subsequently triggers a series of events characterized by calcium overload ...
Anqi Liu, Peng Peng, Changze Wei, Fanhui Meng, Xiaoyao Huang, Peisheng Liu, Siyuan Fan, Xinyue Cai, Meiling Wu, Zilin Xuan, Qing Liu, Xinyu Qiu, Zhenlai Zhu, Hao Guo   +13 more
wiley   +1 more source

Antiviral Activities of Amniotic Fluid

Experimental Biology and Medicine, 1981
AbstractBecause viral infection in pregnancy can be a threat to the developing fetus, the identification and quantification of any protective factors operating on behalf of the offspring may be important. We have, therefore, assayed human amniotic fluid for factors influencing viral growth and have found that such fluid does not contain substances with
A. Goldstein, M. Lindsey, Jeremiah G. Tilles, K. Dumars, Thomas C. Cesario   +4 more
openaire   +3 more sources

Mining of high throughput screening database reveals AP-1 and autophagy pathways as potential targets for COVID-19 therapeutics [PDF]

arXiv, 2020
The recent global pandemic of Coronavirus Disease 2019 (COVID-19) caused by the new coronavirus SARS-CoV-2 presents an urgent need for new therapeutic candidates. Many efforts have been devoted to screening existing drug libraries with the hope to repurpose approved drugs as potential treatments for COVID-19. However, the antiviral mechanisms of action
arxiv  

Shrimp Virus Regulates ROS Dynamics via the Nrf2 Pathway to Facilitate Viral Replication

Advanced Science, EarlyView.
Viruses manipulate host ROS as a strategy to achieve successful infection. WSSV exploits Nrf2 pathway to maintain ROS homeostasis and establishes a positive feedback loop to facilitate WSSV replication. Wsv220 competitively binds to Keap1 to activate Nrf2. Nrf2 up‐regulates LvG6PDH to produce more NADPH and GSH to eliminate excessive ROS.
Honghui He, Kai Yuan, Junming Pan, Shaoping Weng, Chaozheng Li, Yihong Chen, Jianguo He   +6 more
wiley   +1 more source

Antiviral Activity of Chitosan Nanoparticles Encapsulating Curcumin Against Hepatitis C Virus Genotype 4a in Human Hepatoma Cell Lines [Corrigendum]

International Journal of Nanomedicine, 2021
Loutfy SA, Elberry MH, Farroh KY, et al. Int J Nanomedicine. 2020;15:2699–2715.The authors have advised Figure 8 on page 2712 is incorrect. The correct Figure 8 is shown below.The authors apologize for this error and advise it does not ...
Loutfy SA, Elberry MH, Farroh KY, Mohamed HT, Mohamed AA, Mohamed EB, Faraag AHI, Mousa SA   +7 more
doaj