Results 91 to 100 of about 10,107,380 (301)

Crucial Role of Selenium in the Virucidal Activity of Benzisoselenazol-3(2H)-ones and Related Diselenides

Molecules, 2010
Various N-substituted benzisoselenazol-3(2H)-ones and their non-selenium-containing analogues have been synthesized and tested against selected viruses (HHV-1, EMCV and VSV) to determine the extent to which selenium plays a role in antiviral activity ...
Jacek Mlochowski, Magdalena Pietka-Ottlik, Piotr Potaczek, Egbert Piasecki   +3 more
doaj   +1 more source

Antiviral Activity of Interferon Alpha-2b and Taurine Combination Against SARS-CoV-2 in vitro

Антибиотики и Химиотерапия, 2022
Interferons (IFN) have antiviral activity against many viruses, including SARS-CoV-2. A combination of IFN-a2b and the antioxidant taurine is widely used in the Russian Federation, and its antiviral activity has not been studied before.
N. P. Kartashova, A. V. Ivanina, E. A. Glubokova, I. N. Falynskova, A. A. Poromov, I. A. Leneva   +5 more
doaj   +1 more source

Identification of novel macrolides with antibacterial, anti-inflammatory and type I and III IFN-augmenting activity in airway epithelium [PDF]

, 2016
BACKGROUND: Exacerbations of asthma and COPD are triggered by rhinoviruses. Uncontrolled inflammatory pathways, pathogenic bacterial burden and impaired antiviral immunity are thought to be important factors in disease severity and duration.
Almond, MH, Dhariwal, J, Edwards, MR, Gill, SK, Groves, H, Johnston, SL, Jones, LH, Kilty, I, Porter, JD, Roberts, LR, Tregoning, J, Walton, RP, Watson, J, Wong, E   +13 more
core   +1 more source

The Antimicrobial and Antiviral Activity of Polyphenols from Almond (Prunus dulcis L.) Skin

Nutrients, 2019
Due to their antimicrobial and antiviral activity potential in vitro, polyphenols are gaining a lot of attention from the pharmaceutical and healthcare industries.
Maria Musarra-Pizzo, G. Ginestra, A. Smeriglio, Rosamaria Pennisi, M. Sciortino, G. Mandalari   +5 more
semanticscholar   +1 more source

Antiviral activity of isoindole derivatives

, 2020
The isoindole scaffolds and their related compounds are very important as they have a wide range of biological activities such as anti-inflammatory, antiarrhythmic, nootropic, anxiolytic, sedative, and antimicrobial activities.
F. Csende, Andrea Porkoláb
semanticscholar   +1 more source

Protease inhibitors targeting coronavirus and filovirus entry. [PDF]

, 2015
In order to gain entry into cells, diverse viruses, including Ebola virus, SARS-coronavirus and the emerging MERS-coronavirus, depend on activation of their envelope glycoproteins by host cell proteases.
Agudelo, Juliet, Barnard, Dale, Carrion, Ricardo, Lu, Kai, McKerrow, James H, Nunneley, Jerritt W, Pöhlmann, Stefan, Renslo, Adam R, Simmons, Graham, Vedantham, Punitha, Zhou, Yanchen   +10 more
core   +1 more source

Exosomes Exploit the Virus Entry Machinery and Pathway To Transmit Alpha Interferon-Induced Antiviral Activity

Journal of Virology, 2018
Our previous study showed that LNPC-derived exosomes could transmit IFN-α-induced antiviral activity to HBV replicating hepatocytes, but the concrete transmission mechanisms, which include exosome entry and exosomal cargo release, remain unclear. In this
Zhenlan Yao, Y. Qiao, Xiaofang Li, Jieliang Chen, Jiahui Ding, Lu Bai, F. Shen, Bisheng Shi, Jia Liu, Lu Peng, Jianhua Li, Zhenghong Yuan   +11 more
semanticscholar   +1 more source

SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate

Nature Communications, 2020
Antiviral strategies to inhibit Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) and the pathogenic consequences of COVID-19 are urgently required.
D. Olagnier, E. Farahani, Jacob Thyrsted, Julia Blay-Cadanet, Angela Herengt, M. Idorn, A. Hait, B. Hernáez, Alice Knudsen, M. B. Iversen, Mirjam Schilling, S. Jørgensen, Michelle M. Thomsen, L. Reinert, M. Lappe, Huy-Dung Hoang, V. Gilchrist, A. L. Hansen, Rasmus Ottosen, Camilla G Nielsen, Charlotte Møller, D. van der Horst, S. Peri, Siddharth Balachandran, Jinrong Huang, M. Jakobsen, Esben B. Svenningsen, T. Poulsen, Lydia Bartsch, Anne L. Thielke, Yonglun Luo, T. Alain, J. Rehwinkel, A. Alcamí, J. Hiscott, T. Mogensen, S. Paludan, C. Holm   +37 more
semanticscholar   +1 more source

Comparación in vitro de aciclovir, ganciclovir y cidofovir contra alfa-herpesvirus equino 3 y evaluación de la eficacia de los mismos frente a 6 aislamientos de campo del virus [PDF]

, 2018
El alfa-herpesvirus equino 3 (EHV3) es el agente etiológico del exantema coital equino (ECE), enfermedad venérea, altamente contagiosa y caracterizada por la aparición de pápulas, vesículas, pústulas y úlceras en los genitales externos de yeguas y ...
Barrandeguy, María, Parreño, Gladys Viviana, Thiry, Etienne, Tordoya, María S., Vissani, María Aldana, Zabal, Osvaldo Alfredo   +5 more
core   +1 more source

Antiviral activities of extremophilic actinomycetes extracts from Kazakhstan’s unique ecosystems against influenza viruses and paramyxoviruses

Virology Journal, 2019
Background Commercially available antiviral drugs, when used in the treatment of viral infections, do not always result in success. This is an urgent problem currently that needs to be addressed because several viruses including influenza and ...
Vladimir Berezin, Diyora Abdukhakimova, Lyudmila Trenozhnikova, Andrey Bogoyavlenskiy, Aizhan Turmagambetova, Alpamys Issanov, Azliyati Azizan   +6 more
doaj   +1 more source