Results 331 to 340 of about 10,450,245 (405)

A Streamlined High Performance Liquid Chromatography with Tandem Mass Spectrometry Based Workflow for Rapid Screening of Cellular Accumulation of Small Molecules

open access: yesChemMedChem, EarlyView.
This study uses six small‐molecule inhibitors to evaluate optimal cellular accumulation assay conditions in a 96‐well format with high performance liquid chromatography with tandem mass spectrometry detection. The obtained medium to high‐throughput workflow is suitable for reliably identifying cellular accumulation, valuable for preclinical selection ...
Alina Metzen, Katharina Rox
wiley   +1 more source

Antiviral activity of plant species from Tierra del Fuego

open access: green, 2019
João E. Vale Aguilar   +5 more
openalex   +1 more source

Monodentate Phosphine Modulation in Cyclometallated Platinum(II) Complexes for Antileishmanial, Antiviral, and Antitumor Applications

open access: yesChemMedChem, EarlyView.
Schematic representation depicting the influence of phosphine ligand identity on the biological and physicochemical characteristics of Pt(II) complexes: PTA promotes antileishmanial activity, PPh2(Php–COOH) strengthens antiviral activity, and TCEP enhances fluorescence.
Antonio A. de Oliveira‐Neto   +12 more
wiley   +1 more source

SARS-CoV-2 NSP14 inhibitor exhibits potent antiviral activity and reverses NSP14-driven host modulation. [PDF]

open access: yesNat Commun
Luo M   +22 more
europepmc   +1 more source

Identification and Characterization of Antiviral Activity of Synthetic Compounds Against Mayaro Virus. [PDF]

open access: yesPharmaceuticals (Basel)
Andreolla AP   +11 more
europepmc   +1 more source

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