Results 251 to 260 of about 4,679,298 (290)
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Trends in Pharmacological Sciences, 1989
Recently the first report of zidovudine-resistant human immunodeficiency virus obtained from AIDS patients was published. Resistance to antiviral agents may result from single point mutations in the virus genome. Several mechanisms of resistance have already been elucidated at the biochemical level but the clinical significance of drug resistance is ...
H J, Field, S E, Goldthorpe
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Recently the first report of zidovudine-resistant human immunodeficiency virus obtained from AIDS patients was published. Resistance to antiviral agents may result from single point mutations in the virus genome. Several mechanisms of resistance have already been elucidated at the biochemical level but the clinical significance of drug resistance is ...
H J, Field, S E, Goldthorpe
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Archives of Pediatrics & Adolescent Medicine, 1989
Pediatricians are made familiar with antiviral drugs and are provided with specific recommendations for treatment of viral diseases. The antiviral drugs in clinical use today are discussed in terms of their doses, routes of administration, mechanisms of action, established and potential efficacies, and toxicities.
H H, Balfour, J A, Englund
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Pediatricians are made familiar with antiviral drugs and are provided with specific recommendations for treatment of viral diseases. The antiviral drugs in clinical use today are discussed in terms of their doses, routes of administration, mechanisms of action, established and potential efficacies, and toxicities.
H H, Balfour, J A, Englund
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Expert Opinion on Emerging Drugs, 2008
Foremost among the newly described antiviral agents that may be developed into drugs are, for the treatment of human papilloma virus (HPV) infections, cPrPMEDAP; for the treatment of herpes simplex virus (HSV) infections, BAY 57-1293; for the treatment of varicella-zoster virus (VZV) infections, FV-100 (prodrug of Cf 1743); for the treatment of ...
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Foremost among the newly described antiviral agents that may be developed into drugs are, for the treatment of human papilloma virus (HPV) infections, cPrPMEDAP; for the treatment of herpes simplex virus (HSV) infections, BAY 57-1293; for the treatment of varicella-zoster virus (VZV) infections, FV-100 (prodrug of Cf 1743); for the treatment of ...
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Antiviral Research, 2006
Almost 30 years ago it was proposed that the selection for antiviral drug resistance should be used as an indicator of antiviral drug activity. In addition to discriminating between cellular toxicity and specific activity directed against a viral target, drug resistant mutants have been used to confirm the mechanism of action of antiviral drugs, to ...
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Almost 30 years ago it was proposed that the selection for antiviral drug resistance should be used as an indicator of antiviral drug activity. In addition to discriminating between cellular toxicity and specific activity directed against a viral target, drug resistant mutants have been used to confirm the mechanism of action of antiviral drugs, to ...
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Medical Clinics of North America, 1983
A number of antiviral compounds are currently available, and several others are of great interest. Trifluridine, idoxuridine, and vidarabine are effective topically in herpes simplex virus keratoconjunctivitis infection. Vidarabine (and presumably acyclovir) is effective in herpes simplex virus encephalitis and in herpes zoster infections in the ...
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A number of antiviral compounds are currently available, and several others are of great interest. Trifluridine, idoxuridine, and vidarabine are effective topically in herpes simplex virus keratoconjunctivitis infection. Vidarabine (and presumably acyclovir) is effective in herpes simplex virus encephalitis and in herpes zoster infections in the ...
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Fifty Years in Search of Selective Antiviral Drugs.
Journal of Medicinal Chemistry, 2019Fifty years of research (1968-2018) toward the identification of selective antiviral drugs have been primarily focused on antiviral compounds active against DNA viruses (HSV, VZV, CMV, HBV) and retroviruses (HIV).
E. De Clercq
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Analytical strategies for the determination of antiviral drugs in the aquatic environment
Trends in Environmental Analytical Chemistry, 2019Antiviral drugs are a therapeutic class of medicines that have garnered interest among the public around the globe. High prescription and consumption rates, seasonal peak emissions due to frequent outbreaks of influenza, and important spatial ...
C. Nannou +5 more
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Drug and Therapeutics Bulletin, 1974
Viruses are divided into two classes according to whether their nucleic acid is DNA or RNA. DNA viruses of clinical importance include herpes simplex, varicella zoster, adenoviruses, variola, vaccinia, verruca and molluscum contagiosum. Drugs available for the specific treatment of some of the diseases caused by these agents are shown in the table ...
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Viruses are divided into two classes according to whether their nucleic acid is DNA or RNA. DNA viruses of clinical importance include herpes simplex, varicella zoster, adenoviruses, variola, vaccinia, verruca and molluscum contagiosum. Drugs available for the specific treatment of some of the diseases caused by these agents are shown in the table ...
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