Results 181 to 190 of about 76,225 (259)

Evidence-to-Recommendation Framework for 2026 ACE Clinical Guideline on upper respiratory tract infections - rational antimicrobial use. [PDF]

Singapore Med J
Lim B, Chua SC, Xu R, Ricci V, Kim PA, Expert Group for URTI ACG.   +5 more
europepmc   +1 more source

An ATP‐Driven N Protein–DDX21 Molecular Switch Dynamically Controls SARS‐CoV‐2 RNA G‐Quadruplex Heterogeneity

Advanced Science, EarlyView.
An ATP‐driven molecular switch, comprising viral nucleocapsid (N) protein and host helicase DDX21, dynamically modulates SARS‐CoV‐2 RNA G‐quadruplex (G4) heterogeneity. These viral G4s feature non‐canonical ion‐dependence and act as energy‐sensitive structural checkpoints.
Ya‐Ting Zheng, Li‐Yan Zhai, Jie Jin, Qiu‐Ying Chen, Hang Fu, Xue‐Qian Sun, Ying Lu, Hui Li, Xi‐Miao Hou   +8 more
wiley   +1 more source

Eligible but missing out: a qualitative study of access to COVID-19 antivirals in Australia. [PDF]

BMC Health Serv Res
Campbell E, Williams J, Degeling C.
europepmc   +1 more source

Beyond Conventional: A Review of Phytochemical‐Hydrogel Systems Enhanced by AI and 3D Printing for Chronic Wound Management

Advanced Science, EarlyView.
This review systematically bridges chronic wound pathology with natural phytochemical hydrogel therapeutics. A pathology‐to‐phytochemical mechanistic mapping framework is established, linking specific wound hallmarks to targeted phytochemical interventions.
Yitao Zhou, Xing Liu, Cuiyi Wang, Xiaoxuan Zhao, Pengrun Zhang, Jingjing Gu, Qiuhua Sun, Malcolm Xing, Yeqin Yang   +8 more
wiley   +1 more source

Competitive Fitness of Cytomegalovirus Mutants Bearing Changes in the UL56 Terminase Subunit, Associated with Letermovir-Resistance, in Presence and Absence of Antivirals. [PDF]

Viruses
Andrei G, Gillemot S, Snoeck R.
europepmc   +1 more source

Unlocking Li/Mg‐Based Photochemical Nitration Platforms for Anticancer Drug Discovery

Advanced Science, EarlyView.
Two low‐toxicity light main‐group metal photochemical systems based on lithium and magnesium are constructed for selective C(sp2)‐H (di)nitration of anilines. The obtained dinitrated products exhibit anti‐HCC (hepatocellular carcinoma) and anti‐KYSE30 cell activities, holding promise as novel antitumor candidates.
Qian Wan, Jiali Zhu, Shanshuo Liu, Luchuan Ou, Huizhen Wang, Yu Lan, Zhou Dong, Yihang Bai, Wei Yang, Shihan Liu, Yan Qiao, Shi‐Jun Li, Zhigang Ren, Linbin Niu   +13 more
wiley   +1 more source

Retrospective Drug Utilization Pattern of the Use of Antivirals and Its Outcome in Hospitalized COVID-19 Patients in a Tertiary Care Hospital in Mumbai From July to October 2020. [PDF]

Cureus
Marolia KR, Nerurkar RP.
europepmc   +1 more source

Fermentation Potentials of Baobab Pulp Extract in Soy Yoghurt Production

AgriFood: Journal of Agricultural Products for Food, EarlyView.
The research work was about the importance of sourcing for alternative inoculants to replace the main inoculants regularly used for yoghurt production. The search for baobab pulp extract as replacement yielded result, as soy yoghurt was successfully produced.
Adegbola Oladele Dauda, Nahim Mokolade Adeagbo, Quadri Idowu Akinremi, Taofiqat Damilola Maiyaki, Adedamola Israel Abioye, Zulfiqoh Tolani AbdulAkeem, Damilare Johnson Folaranmi   +6 more
wiley   +1 more source

Treatment of hepatitis C in children and adolescents: our experience to date, current status, and prospects. [PDF]

Clin Exp Hepatol
Pokorska-Śpiewak M, Talarek E, Aniszewska M, Dobrzeniecka A, Marczyńska MM.   +4 more
europepmc   +1 more source

Machine Learning‐Enhanced Random Matrix Theory Design for Human Immunodeficiency Virus Vaccine Development

Advanced Intelligent Discovery, EarlyView.
This study integrates random matrix theory (RMT) and principal component analysis (PCA) to improve the identification of correlated regions in HIV protein sequences for vaccine design. PCA validation enhances the reliability of RMT‐derived correlations, particularly in small‐sample, high‐dimensional datasets, enabling more accurate detection of ...
Mariyam Siddiqah, Muhammad Zulqarnain Zeb, Muhammad Husnain Zeb, Babar Shabbir   +3 more
wiley   +1 more source