Results 211 to 220 of about 94,016 (287)

Mechanism of SARS-CoV-2 resistance to nucleotide analog-based antivirals. [PDF]

open access: yesNat Commun
Liu C   +5 more
europepmc   +1 more source

Synthesis of Sulfur Heterocycles by Palladium‐Catalyzed Cyclization

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
In spite of the well‐known palladium thiophilicity, sulfur‐containing acyclic substrates may efficiently undergo several different kinds of palladium‐catalyzed cyclization processes leading to highly important sulfur heterocycles in one synthetic step. Advances in this challenging and stimulating field of research are presented in this review.
Bartolo Gabriele
wiley   +1 more source

Synthesis of Heterocyclic Scaffolds from Nitrobenzyl Alcohols Using Reduction‐Generated Azaquinone Methides and Cyclization

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Intramolecular cyclization to quench an in situ reduction‐generated azaquinone methide is a strategy that could be used for late‐stage heterocycle synthesis. Herein, synthetically accessible 4‐nitrobenzyl alcohols with a nucleophilic handle adjacent to the benzyl alcohol group are reduced under mild conditions to afford six‐ and seven‐membered ...
Harrison M. Lewin   +4 more
wiley   +1 more source

COVID-19 Antiviral Prescription Receipt Among Outpatients Aged ≥65 Years - United States, June 1, 2023-September 30, 2025. [PDF]

open access: yesMMWR Morb Mortal Wkly Rep
Raykin J   +8 more
europepmc   +1 more source

Cuproptosis‐Related Genes in Immune Infiltration and Diagnosis in Hepatitis B Virus‐Related Acute Liver Failure

open access: yesExploration, EarlyView.
The role of cuproptosis in HBV‐ALF was explored via bioinformatics and liver biopsy tissues. There are some crosstalks among cuproptosis, immune infiltration, and ferroptosis (The figure was created by Bio Render). ABSTRACT Hepatitis B virus (HBV) infection poses a significant challenge to global health, particularly in developing countries such as ...
Jingwen Deng   +10 more
wiley   +1 more source

Limitations of acyclovir and identification of potent HSV antivirals using 3D bioprinted human skin equivalents. [PDF]

open access: yesNat Commun
Ellison ST   +14 more
europepmc   +1 more source

Designing digital public services [PDF]

open access: yes, 2011
Rainford, Paul, Tinkler, Jane
core  

Surmounting Recalcitrant Airway Inflammatory Disorders With a Multi‐Targeting Therapeutic Strategy by Tannic Acid‐Modified CuInP2S6 Nanosheets

open access: yesExploration, EarlyView.
Our findings underscore a multi‐targeting strategy for severe airway inflammation that multi‐targeting nanoformulation C‐TA1 markedly attenuated airway inflammation by (1) cfDNA elimination to alleviate neutrophilic/eosinophilic inflammation mediated by the TLR9 pathway, (2) prevention of RONS‐induced tissue injury and inflammatory response, (3 ...
Ming Liu   +10 more
wiley   +1 more source

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