Results 131 to 140 of about 3,774,685 (294)
Integrated structural analysis of N. vulgaris formate dehydrogenase AB, an enzyme with applications in climate change mitigation, is reported. The substrate/product diffusion pathways were fully mapped, and a retention site was identified that transiently holds substrates and has a key role in CO2‐reducing activity.
Guilherme Vilela‐Alves +8 more
wiley +2 more sources
A trust‐region funnel algorithm for gray‐box optimization
Abstract Gray‐box optimization, where parts of optimization problems are represented by algebraic models while others are treated as black‐box models lacking analytic derivatives, remains a challenge. Trust‐region (TR) methods provide a robust framework for gray‐box problems through local reduced models (RMs) for black‐box components, but they are ...
Gul Hameed +4 more
wiley +1 more source
Depolymerization and Reuse of Polycarbonates: Emerging Classes, Mechanisms and Challenges
This review collects the latest developments in the area of chemical and catalytic polycarbonate recycling strategies and includes the controlled degradation of similar types of macromolecules. Apart from the main strategies for deconstruction, the key mechanistic features of these depolymerization processes are also discussed together with the ...
Davide Rigo +4 more
wiley +2 more sources
This work shows resonant tunneling diode‐based opto‐electronic spiking neurons enabling fast edge detection in time series, a two‐layer photonic spiking neural network for complex classification, and a depth‐tunable photonic spiking memory system. Neuromorphic computing—modeled after the functionality and efficiency of biological neural systems—offers ...
Dafydd Owen‐Newns +8 more
wiley +1 more source
Abstract Premise Insect herbivory is a major biotic factor shaping plant populations and driving the evolution of defensive traits. Polyploidy (whole‐genome duplication) often induces substantial phenotypic and genotypic changes that may affect species interactions, including herbivory.
Antonio J. Manzaneda +4 more
wiley +1 more source
The Insistence of Blackness and the Persistence of Antiblackness in Ireland
ABSTRACT This paper positions Ireland as a critical site for examining the insistence of blackness and an antiblackness created and sustained through Irish ethnonationalist imaginaries and exclusionary processes. Drawing on connected sociologies and Irish Black Studies, this enquiry argues that antiblackness in Ireland operates as a generational force,
Philomena Mullen
wiley +1 more source
Objective Immunothrombosis contributes to ischemic stroke pathophysiology through neutrophil extracellular trap (NET) formation, which promotes thrombus stabilization and microvascular dysfunction. DNase1 is the principal endonuclease responsible for NET degradation.
B. Díaz‐Benito +10 more
wiley +1 more source
Antonio es un proyecto ilustrado sobre una historia basada en hechos reales. Esta historia misteriosa surge de la necesidad de expresar de forma física el sentimiento de angustia e incertidumbre que pueden causar a una persona los sueños premonitorios.
openaire +1 more source
Sex‐Specific Genetic Architecture of ALS: Evidence of a Female Protective Effect?
Background Amyotrophic lateral sclerosis (ALS) shows sex differences in incidence and age of onset, yet the underlying biological mechanisms remain poorly understood. Methods We investigated sex‐specific genetic architecture in an Italian ALS cohort with whole‐genome sequencing (1,333 ALS cases, 755 controls).
Maurizio Grassano +20 more
wiley +1 more source

