Results 51 to 60 of about 3,265 (285)

The Antonym-Heuristic: Automatic Falsification of Valenced Information [PDF]

, 2011
The aim of the present research was to find evidence for the existence of an antonym-heuristic when valenced (positive or negative) information is falsified.
Weil, Rebecca
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Usage of fMRI for pre-surgical planning in brain tumor and vascular lesion patients: Task and statistical threshold effects on language lateralization

NeuroImage: Clinical, 2015
Background and purpose: Functional magnetic resonance imaging (fMRI) is a non-invasive pre-surgical tool used to assess localization and lateralization of language function in brain tumor and vascular lesion patients in order to guide neurosurgeons as ...
Tanvi N. Nadkarni, Matthew J. Andreoli, Veena A. Nair, Peng Yin, Brittany M. Young, Bornali Kundu, Joshua Pankratz, Andrew Radtke, Ryan Holdsworth, John S. Kuo, Aaron S. Field, Mustafa K. Baskaya, Chad H. Moritz, M. Elizabeth Meyerand, Vivek Prabhakaran   +14 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Negated Adjectives and Antonyms in Distributional Semantics: not similar?

IJCoL, 2019
We investigate the relation between negated adjectives and antonyms pairs in English (e.g., not cold vs. hot - cold) using Distributional Semantics. We build vector representations of a set of antonyms and their negations on the basis of their contexts ...
Laura Aina, Raffaella Bernardi, Raquel Fernández   +2 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Electrophysiological Responses to Expectancy Violations in Semantic and Gambling Tasks: A Comparison of Different EEG Reference Approaches

Frontiers in Neuroscience, 2018
Dynamically evaluating the outcomes of our actions and thoughts is a fundamental cognitive ability. Given its excellent temporal resolution, the event-related potential (ERP) technology has been used to address this issue. The feedback-related negativity
Ya Li, Yongchun Wang, Baoqiang Zhang, Yonghui Wang, Xiaolin Zhou, Xiaolin Zhou, Xiaolin Zhou, Xiaolin Zhou   +7 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

The Comparative Effect of Antonym in-Text Glosses and Description in-Text Glosses on EFL Learners' Reading Comprehensio [PDF]

Journal of English Language Pedagogy and Practice, 2019
The present study was carried out to investigate the comparative effect of antonym in-text glosses and description in-text glosses on a group of Iranian EFL learners' reading comprehension.
Hanieh Ghasemi, Mona Khabiri
doaj