Results 31 to 40 of about 345,692 (191)
TNF-?, cukrzyca typu 1 i limfocyty T regulatorowe [PDF]
Pediatric Endocrinology, Diabetes and Metabolism, 2010 W badaniach na modelach zwierzęcych cukrzycy typu 1 (DM1), a także na ludzkich komórkach regulatorowych wykazano, że TNF-? upośledza zdolność tych komórek do hamowania choroby. Podanie myszom NOD TNF-? zmniejszało odsetek limfocytów Treg, z kolei terapia
Monika Ryba, Jolanta Myśliwska
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Zespół zmęczenia w przebiegu sarkoidozy [PDF]
, 2016 Sarkoidoza jest chorobą zapalną o nieznanej etiologii. Nieserowaciejące ziarniniaki tworzą się najczęściej w węzłach chłonnych w obrębie klatki piersiowej i w płucach, choć przebieg i obraz kliniczny mogą być skomplikowane przez inne lokalizacje ...
Górski, Witold, Piotrowski, Wojciech J.
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Cell Death and Disease, 2019 Endothelium (EC) is a key component of blood–brain barrier (BBB), and has an important position in the neurovascular unit. Its dysfunction and death after cerebral ischemic/reperfusion (I/R) injury not only promote evolution of neuroinflammation and ...
An-qi Chen +13 more
semanticscholar +1 more source
Selective Targeting of TNF Receptors as a Novel Therapeutic Approach
Frontiers in Cell and Developmental Biology, 2020 Tumor necrosis factor (TNF) is a central regulator of immunity. Due to its dominant pro-inflammatory effects, drugs that neutralize TNF were developed and are clinically used to treat inflammatory and autoimmune diseases, such as rheumatoid arthritis ...
R. Fischer +2 more
semanticscholar +1 more source
Complexity of TNF-α Signaling in Heart Disease
Journal of Clinical Medicine, 2020 Heart disease is a leading cause of death with unmet clinical needs for targeted treatment options. Tumor necrosis factor alpha (TNF-α) represents a master pro-inflammatory cytokine that plays an important role in many immunopathogenic processes.
F. Rolski, P. Błyszczuk
semanticscholar +1 more source
Spondyloartropatia a zmiany narządowe — kompleksowe podejście do pacjenta [PDF]
, 2017 Spondyloartropatia zapalna (SpA), czyli zapalenie stawów z zajęciem stawów kręgosłupa, to przewlekła choroba zapalna z różnorodnymi manifestacjami klinicznymi, obejmującymi objawy ze strony układu mięśniowo-szkieletowego oraz objawy pozastawowe.
Felis-Giemza, Anna
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The TNF Family of Ligands and Receptors: Communication Modules in the Immune System and Beyond.
Physiological Reviews, 2019 The tumor necrosis factor (TNF) and TNF receptor (TNFR) superfamilies (TNFSF/TNFRSF) include 19 ligands and 29 receptors that play important roles in the modulation of cellular functions.
Catherine Dostert +3 more
semanticscholar +1 more source
Inflammatory bowel diseases in pregnant women - current state of knowledge [PDF]
, 2023 Introduction and objective: Inflammatory bowel diseases (IBD) are a group of chronic inflammatory diseases. Usually they affect young people, often during pregnancy.
Antonik, Dominika +9 more
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Scientific Reports, 2018 We carried out systematic review and meta-analysis to evaluate whether peripheral levels of pro-inflammatory markers including Interleukin-1 beta (IL-1β), Interleukin-6 (IL-6), Tumor Necrosis Factor-α (TNF- α) and C-Reactive Protein (CRP) are ...
A. Ng +6 more
semanticscholar +1 more source
Efficacy of the first and subsequent courses of anti-TNF therapy in patients with ankylosing spondylitis - results from the Czech National Register ATTRA Skuteczność pierwszego i kolejnych kursów terapii anty-TNF u pacjentów z zesztywniającym zapaleniem s [PDF]
, 2012 S u m m a r y Background: Efficacy of switching of anti-tumour necrosis factor (anti-TNF) in ankylosing spondylitis (AS) in real clinical practice is not fully known.
Gia Lo, Reu Ma
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