Results 51 to 60 of about 58,847 (249)

Diallyl Trisulfide From Garlic Regulates RAB18 Phase Separation to Inhibit Lipophagy and Induce Cuproptosis in Hepatic Stellate Cells for Antifibrotic Effects

Advanced Science, EarlyView.
Diallyl trisulfides (DATs) selectively induce cuproptosis in hepatic stellate cells (HSCs) by targeting Ras‐related protein Rab‐18 (RAB18) and regulating lipophagy. DATs promote RAB18 phase separation, enhance mitochondrial‐associated membrane structures (MAMs) formation, and increase succinylation of dihydrolipoamide dehydrogenase (DLD) at K320.
Haoyuan Tian, Shujiang Sun, Xinran Qiu, Junrui Wang, Yuanyuan Gao, Jianmei Chen, Xiang Han, Zhengyang Bao, Xiaohan Guo, Yuqi Sun, Yuxin Lin, Mengru Hu, Feng Zhang, Zili Zhang, Feixia Wang, Shizhong Zheng, Jiangjuan Shao   +16 more
wiley   +1 more source

A review of helochelydrid shell material from late Albian to early Cenomanian greensands of Southern England, United Kingdom

The Anatomical Record, EarlyView., 2022
Abstract A number of helochelydrid turtle shell remains were recovered over the course of the 19th century from mid‐Cretaceous sediments throughout Southern England, including the poorly figured and described types of Trachydermochelys phlyctaenus from the Cambridge Greensand of Cambridgeshire, Plastremys lata from the Upper Greensand of the Isle of ...
Walter G. Joyce
wiley   +1 more source

Ellagic acid regulates Wnt/?-catenin signaling pathway and CDK8 in HCT 116 and HT 29 colon cancer cells

Bangladesh Journal of Pharmacology, 2015
Colorectal cancer is one of the leading causes of death worldwide. Wnt/?-catenin signalling pathway plays a central role in normal cellular responses, making it a potent target in cancer therapy.
Yang Fang, Hong Zhou, Jian-Fu Xia, Jie-Jun Lin, Ri-Zeng Li, Da-Qing Yang, Mai-Yu Xu, Xiao-Yang Li   +7 more
doaj  

Shell characterization of the youngest valid species of the European Eocene genus Neochelys (Pleurodira, Podocnemididae): The Spanish Bartonian Neochelys salmanticensis

The Anatomical Record, EarlyView., 2023
Abstract The freshwater pleurodiran turtle Neochelys is the best‐represented member of Podocnemididae in the European record, being known by eight Eocene species. The youngest of them is the Bartonian (middle Eocene) Neochelys salmanticensis, from the Duero Basin (Salamanca Province, Central Spain).
Adán Pérez‐García, Andrea Guerrero, Santiago Martín de Jesús, Francisco Ortega   +3 more
wiley   +1 more source

Protrusion pyramidale périanale

The Pan African Medical Journal, 2014
La protrusion pyramidale périanale est une entité d'individualisation récente, assez rare, touchant presque exclusivement le sexe féminin souvent en bas âge, d'origine congénitale, fonctionnelle ou associée au lichen scléroatrophique.
Nihal Bekkali, Jalal El Benaye
doaj   +1 more source

Treatment of Gastrointestinal Sphincters Spasms with Botulinum Toxin A

Toxins, 2015
Botulinum toxin A inhibits neuromuscular transmission. It has become a drug with many indications. The range of clinical applications has grown to encompass several neurological and non-neurological conditions.
Giuseppe Brisinda, Nicola Sivestrini, Giuseppe Bianco, Giorgio Maria   +3 more
doaj   +1 more source

Study on the factors influencing the prognosis after perianal abscess surgery

BMC Gastroenterology, 2023
Objective To study the influence of clinical characteristics and diagnosis and treatment methods of perianal abscess on postoperative recurrence or formation of anal fistula to provide a basis for selecting appropriate surgical and inspection methods for
Shujiang Dong, Bingxue Chen, Jian Zhang
doaj   +1 more source

Perianal Angioleiomyoma: A Case Report and Review of the Literature

Journal of Medical Ultrasound
Angioleiomyomas are rare benign tumors, which take origin from smooth muscle fibers of the tunica media of veins. Even though angioleiomyomas can appear anywhere in the body, these masses are rarely occurred in the gastrointestinal system.
Ioannis D Gkegkes, Vassilis Milionis, Nikolaos Goutas, Apostolos P Stamatiadis   +3 more
doaj   +1 more source

Hospitalizations associated with malignant neoplasia and in situ carcinoma in the anus and penis in men and women during a 5-year period (2009–2013) in Spain: An epidemiological study

Human Vaccines & Immunotherapeutics, 2017
Background Approximately 40,000 new cases of anal cancer and 26,000 new cases of penile cancer occurred in 2012 worldwide. Human Papillomavirus (HPV) infection is responsible for 88.3% and 33.0% of these cancers, respectively.
Noelia López, Ángel Gil-de-Miguel, Raquel Pascual-García, Ruth Gil-Prieto   +3 more
doaj   +1 more source

Silver(I) pyridinyl complexes with benzothiazole, thiophene, and furan moieties: DNA/protein‐binding, antibacterial, antioxidant, and anticancer studies

Archiv der Pharmazie, Volume 356, Issue 1, January 2023., 2023
Nine Ag(I) complexes of Schiff bases containing thiophene, furan, and pyridine moieties were synthesized and tested for their in vitro antibacterial, antioxidant, and anticancer activities and DNA/bovine serum albumin binding. The nine Ag(I) complexes bound to calf thymus‐DNA by an intercalative binding mode, with the complex bearing a benzothiazole ...
Adesola A. Adeleke, Md. Shahidul Islam, Bernard Omondi   +2 more
wiley   +1 more source