Results 101 to 110 of about 21,419 (297)

Losses of expression of the antigens A, Lea and Lex and over-expression of Ley in carcinomas and HG-SIL of the uterine cervix [PDF]

, 2008
Background The glycosylation of a great number of molecules, glyco-protein or glycolipids, has been of interest for decades. Objective To compare the expressive patterns of the isoantigenic determinants of histo-blood groups ABH and Lewis in squamous and
Ernesto Moro-Rodríguez, Emilio Álvarez-Fernández   +1 more
core   +1 more source

Development and validation of a multimodal model based on histopathological and computed tomography imaging for predicting survival outcomes in stage III colorectal cancer

VIEW, EarlyView.
Patients with stage III colorectal cancer exhibit substantial heterogeneity in clinical outcomes despite receiving standardized treatments, which complicates accurate risk stratification. In this study, we integrated features derived from routine histopathological slides and preoperative computed tomography scans using machine learning to develop a ...
Danyi Li, Zhangxin Zhao, Genxia Wei, Weihao Qiu, Zhihao Lin, Jiankun He, Bingbing Li, Jing Wang, Lisheng Zheng, Feiyan Feng, Xiangkun Wu, Zhengyu Zhang, Jinbang Li, Mingxing Qiu, Shujing Guo, Chenglong Zhao, Ying Tan, Yueping Liu, Qingling Zhang, Yu Zhang, Li Liang   +20 more
wiley   +1 more source

Exploring the interdependencies of research funders in the UK [PDF]

, 2014
Investment in medical research is vital to the continuing improvement of the UK's health and wealth. It is through research that we expand our understanding of disease and develop new treatments for patients.
Crane, P, Farrell, C, Garau, M, Grassano, N, Hernandez-Villafuerte, K, Hopkins, M M, Hutton, J, Lang, F, Mawer, A, Pateman, C, Rotolo, D, Shah, K, Sharp, T, Sussex, J   +13 more
core   +1 more source

Pre-treatment tumour PET metrics and clinical outcomes of anal cancer in patients living with and without HIV

Acta Oncologica
Background/purpose: To investigate if pre-treatment tumour positron-emission tomography (PET) metrics’ prognostic efficacy changes with HIV or viral load (VL) in anal squamous cell carcinoma (ASCC).
Michael Pennock, N. Patrik Brodin, Christian Velten, Megi Gjini, Nitin Ohri, Chandan Guha, Shalom Kalnicki, Wolfgang A. Tome, Madhur K. Garg, Rafi Kabarriti   +9 more
doaj   +1 more source

Granular cell tumor of anal border

Journal of Coloproctology, 2016
The objective of this report is to describe a case of granular cell tumor of the anal border and to review the most relevant topics of the literature on the subject.
Angelo Fontes Araújo, Igor Blohem Vasconcelos, Jadeilton Jipso de Souza Dias, Luciano Santana de Miranda Ferreira, Rodrigo Guimarães Andrade, Paulo César Boente Santos   +5 more
doaj   +1 more source

Impact of an ERAS‐Based Surgical Care Bundle Implementation for Preventing Anastomotic Leakage in Minimally Invasive Low Anterior Resection for Rectal Cancer: A Retrospective Cohort Study

World Journal of Surgery, EarlyView.
Anastomotic leakage (AL) remains a severe complication after low anterior resection (LAR) for rectal cancer, despite advances in minimally invasive (MI) techniques. This study aimed to evaluate the impact of a surgery‐focused care bundle, implemented on an enhanced recovery after surgery (ERAS)‐based perioperative protocol, on preventing AL and ...
Koji Tamura, Takaaki Fujimoto, Jinghui Zhang, Kinuko Nagayoshi, Yusuke Mizuuchi, Kohei Horioka, Naoki Ikenaga, Kohei Nakata, Kenoki Ohuchida, Masafumi Nakamura   +9 more
wiley   +1 more source

Prognostic Significance of the Modified Glasgow Prognostic Score in Patients With Stage IV Melanoma Receiving Immune Checkpoint Inhibitors: A Single‐Center Retrospective Study

The Journal of Dermatology, EarlyView.
ABSTRACT Immune checkpoint inhibitors (ICIs) have transformed the treatment landscape for malignant melanoma (MM). However, given variable response rates and potential toxicities, identifying robust biomarkers is crucial. We investigated whether the modified Glasgow Prognostic Score (mGPS) predicts treatment efficacy and toxicity in Asian patients with
Ken Horisaki, Shusuke Yoshikawa, Wataru Omata, Arata Tsutsumida, Yoshio Kiyohara   +4 more
wiley   +1 more source

Expression of the breast differentiation antigen NY-BR-1 in a phyllodes tumor of the vulva [PDF]

, 2018
We describe a phyllodes tumor of borderline malignancy in the labium majus of a 49-year-old woman. The histogenetic origin of phyllodes tumors in the vulva is controversial. Strong immunoreactivity for NY-BR-1, a novel breast differentiation antigen, was
Giger, Olivier, Honegger, Christoph, Lacoste, Elena, Moch, Holger, Padberg, Barbara, Varga, Zsuzsanna   +5 more
core  

Five‐year outcome of laparoscopic transanal total mesorectal excision in a single centre—A training model to acquire a new surgical technique

Surgical Practice, EarlyView.
Abstract Background Laparoscopic transanal total mesorectal excision (TaTME) has been widely adopted globally. Short‐ and long‐term outcomes vary across different localities, especially during the learning phase. Method and patient The first 100 cases of TaTME performed by two experienced colorectal surgeons between 2015 and 2019 were reviewed. The aim
Sophie Sok Fei Hon, Janet Fung Yee Lee, Julie Hoi Yan Ng, Kaori Futaba, Simon Chu, Simon Siu Man Ng   +5 more
wiley   +1 more source

Individualized T3‐4N+ Rectal Cancer Treatment Strategies: Exploring the Efficacy of Preoperative Synchronized Lateral Lymph Node Simultaneous Integrated Boost Radiation Therapy

Asia-Pacific Journal of Clinical Oncology, EarlyView.
Anatomical Diagram: It shows a cross‐section of the pelvic area highlighting the rectum and lateral lymph nodes, which are the focal points of the treatment strategy discussed in the paper. Flowchart: It outlines the treatment process from preoperative synchronized radiation therapy to the subsequent surgical procedures, illustrating the sequence of ...
Xinjue Shi, Siyao Zhong, Xianbin Zheng, Xianxiu Nan, Xuan Liu, Qiteng Liu, Jing Yuan, Yuyan Gao   +7 more
wiley   +1 more source