Results 81 to 90 of about 18,052 (236)

Impact of Metformin and Diabetes on Tumor Response to Total Neoadjuvant Therapy in Advanced Rectal Cancer: A Multicenter Retrospective Cohort Study

Asia-Pacific Journal of Clinical Oncology, EarlyView.
In advanced rectal cancer patients receiving total neoadjuvant therapy (TNT), overall tumor response did not differ by diabetes status or metformin use. However, among diabetic patients, metformin use was associated with higher overall complete response rates. These findings suggest a potential benefit of metformin in enhancing TNT response in diabetic
Sergei Bedrikovetski, Mahima Raju, Tracy Fitzsimmons, Ishraq Murshed, Timothy J. Price, Michael Penniment, Sudarsha Selva‐Nayagam, Tarik Sammour   +7 more
wiley   +1 more source

Seven Years of Watch and Wait With Rectal Cancer—Reflections and Optimisations

ANZ Journal of Surgery, EarlyView.
ABSTRACT Purpose Sir Charles Gairdner Hospital (SCGH) commenced an observation strategy in patients with a complete clinical response, Watch and Wait (W&W), for rectal adenocarcinoma in 2017 using a rigorous surveillance protocol. Our earlier results (2017–2019) have been published.
Ben Finlay, Emma Powell, Anne Long, Rohen White, John Herron, Michael Warner   +5 more
wiley   +1 more source

Melanoma anal, importancia del diagnóstico diferencial con la enfermedad anal benigna

Revista Colombiana de Cirugía
El melanoma anorrectal, descrito inicialmente por Moore en 1857, es un tumor infrecuente y agresivo, cuyo pronóstico suele ser infausto, con una supervivencia a los cinco años menor de 20 %.
David Martínez-Ramos, Rafael García-Calvo, Laura Simón-Monterde, María Jesús Nicolau-Ribera   +3 more
doaj  

Perianal squamous cell carcinoma with high-grade anal intraepithelial neoplasia in an HIV-positive patient using highly active antiretroviral therapy: case report

São Paulo Medical Journal
CONTEXT: Highly active antiretroviral therapy (HAART) has turned human immunodeficiency virus (HIV) infection into a chronic condition, and this has led to increased incidence of anal dysplasia among HIV-positive patients.
Sergio Carlos Nahas, Caio Sergio Rizkallah Nahas, Edesio Vieira da Silva Filho, Jose Eduardo Levi, Fabio Cesar Atui, Carlos Frederico Sparapan Marques   +5 more
doaj   +1 more source

Efficacy and Safety of Anal High‐Grade Squamous Intraepithelial Lesion Treatment Modalities: A Systematic Review

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background There is compelling evidence that treating high‐grade squamous intraepithelial lesions (HSIL), the anal squamous cell cancer (ASCC) precursor, reduces the risk of developing ASCC. Using high‐resolution anoscopy (HRA), surgical excision, ablative and topical therapies are widely used to treat HSIL.
Matthew Joseph Marino, Sophie Jones, Nicholas Reid Caldwell, Catherine Cartwright, Benedict Blacket, Richard Clive Turner   +5 more
wiley   +1 more source

Perception of cure and quality of life in anal cancer survivors

Acta Oncologica
Background and purpose: Anal cancer is treated with chemoradiotherapy and with salvage surgery in case of local failure. Curation rate depends on tumour stage but is overall high (80–90%).
Nina Fanni, Eva Haglind, Sofia Heyman, Mia Johansson, Ying Li, Anna Perman, Eva Angenete   +6 more
doaj   +1 more source

A Systematic Scoping Review of Participant Descriptor, Diversity and Inclusivity Data Reported in Randomised Studies of Post‐Operative Ileus

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Poor reporting of baseline descriptor, diversity and inclusion data is a barrier in surgical research for drawing generalisable conclusions across diverse populations. Post‐operative ileus was used as an exemplar surgical condition to quantify the variation in baseline descriptor, inclusivity and diversity data in randomised ...
Miriam Khalil, Edward Roberts, David G. Jayne, Stephen J. Chapman   +3 more
wiley   +1 more source

Review of Various Perianal Lesions on CT and MRI

Journal of the Korean Society of Radiology
The perianal area consists of complex and diverse anatomical structures. Various conditions can affect this area, including inflammatory diseases, such as perianal abscesses, fistulas, and condyloma acuminata, and malignant tumors, such as mucinous ...
Yoo Jin Park, So Hyun Park, Sungjin Yoon, Hee Joong Lim   +3 more
doaj   +1 more source

Oncovascular Resection in Pelvic Exenteration: A Systematic Review

ANZ Journal of Surgery, EarlyView.
Risk of bias assessment using ROBINS‐1 V2. Selection of the reported result (D7) was judged based on omission of key expected outcomes, including margin status (R0 resection), postoperative complications and mortality. Studies not reporting these outcomes were classified as serious risk of bias, while those with broadly complete but non‐pre‐specified ...
Joshua Richard Burke, Yasmin Oskui, Imogen Samuel, Jonathan Wild, Kilian G. Brown, Jonathan Ghosh, Paul A. Sutton   +6 more
wiley   +1 more source

Uses of Bovine Pericardium in General Surgery

ANZ Journal of Surgery, EarlyView.
Bovine pericardium is a versatile biologic material with expanding applications across general surgery. ABSTRACT Background Bovine pericardium (BP) is increasingly utilised in complex surgical reconstruction because of its favourable biological and mechanical properties.
William A. Ziaziaris, Makaela Bowman, Paul D. Morris, Kilian G. M. Brown, Michael J. Solomon, Jerome M. Laurence   +5 more
wiley   +1 more source