Results 251 to 260 of about 12,749 (324)

Biomolecular Affinities and Cytotoxicity of Copper(I) and Silver(I) Phosphine–Pyridinyl Complexes Against CACO‐2 and CASKI Cell Lines

open access: yesEuropean Journal of Inorganic Chemistry, Volume 28, Issue 15, May 28, 2025.
This study reports Copper(I) and Silver(I) complexes with pyridinyl Schiff base ligands and triphenylphosphine. Their DNA/protein binding and in vitro cytotoxicity were evaluated. All complexes intercalated with calf thymus DNA, bound strongly to proteins, and showed notable cytotoxicity against Caco‐2 and Caski cancer cells, highlighting their promise
Adesola A. Adeleke   +4 more
wiley   +1 more source

DNA methylation and copy number alterations in the progression of HPV‐associated high‐grade vulvar intraepithelial lesion

open access: yesInternational Journal of Cancer, Volume 156, Issue 10, Page 1926-1935, 15 May 2025.
What's new? Patients with human papillomavirus (HPV)‐associated high‐grade vulvar intraepithelial lesion (HSIL) often undergo damaging treatments to prevent progression to cancer. Molecular characterization of HSIL to assess progression risk could reduce the need for aggressive interventions. Here, cancer risk stratification of HSIL was investigated by
Flavia Runello   +8 more
wiley   +1 more source

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