Results 71 to 80 of about 49,725 (243)

Scope of safety requirement in quality certificates used in food production in Brazil [PDF]

open access: yes, 2010
Os certificados ou selos de qualidade são utilizados em diversos países, inclusive no Brasil, com o intuito de diferenciar produtos ou unidades de produção de alimentos.
Araújo, Wilma Maria Coelho   +1 more
core   +1 more source

A judicialização de medicamentos imunoterápicos sem registro na Anvisa: o caso do Estado de São Paulo

open access: yesCadernos Ibero-americanos de Direito Sanitário, 2019
Objetivos: o registro sanitário garante minimamente a segurança nas indicações de bula. Com o julgamento do Recurso Extraordinário (RE) nº 657.718/2019, essa questão não está pacificada.
Daniel Buffone de Oliveira   +5 more
semanticscholar   +1 more source

A segurança do paciente cirúrgico na perspectiva da vigilância sanitária — uma reflexão teórica / Surgical patient safety from the perspective of health surveillance — a theoretical reflection

open access: yesVigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia, 2014
Diversas medidas de prevenção dos riscos relacionados à assistência e à melhoria da saúde são desenvolvidas em favor da segurança do paciente. A segurança do paciente é entendida como a redução, a um mínimo aceitável, do risco de dano desnecessário ...
Heiko Thereza Santana   +9 more
doaj   +1 more source

Effects of consumption of galactooligosaccharides obtained through whey enzymatically modified on the faecal flora and nutritional parameters of hamsters [PDF]

open access: yes, 2017
The aim of this research was to evaluate the influence of wheyenzymatically modified rich in galactooligosaccharides in thenutritional characteristics and effects in the microflora of cecumcontents by the study with Golden Syrian hamsters ...
Burkert, Carlos André V.   +7 more
core  

Public policies on healthcare-associated infections: a Brazil and UK case study [PDF]

open access: yes, 2017
To summarize the historical events and drivers underlying public policy for the prevention and control of healthcare-associated infections in Brazil and in the United Kingdom.
Bishop, Simon   +4 more
core   +4 more sources

Preclinical Pharmacokinetic Assessment of a Promising Vasorelaxant, Analgesic, and Anti‐Inflammatory Prototype 5‐[1‐(4‐Fluorophenyl)‐1H‐pyrazol‐4‐yl]‐2H‐tetrazole (LQFM020) Through Selective Bioanalytical HPLC‐PDA‐Based Method

open access: yesBiomedical Chromatography, Volume 39, Issue 5, May 2025.
ABSTRACT A simple and selective high‐performance liquid chromatography bioanalytical method was developed and validated to determine the pharmacokinetic parameters of 5‐[1‐(4‐fluorophenyl)‐1H‐pyrazol‐4‐yl]‐2H‐tetrazole (LQFM020) with promising vasorelaxant, anti‐inflammatory, and antinociceptive properties while verifying its potential hepatic enzyme ...
Lanussy Porfiro de Oliveira   +10 more
wiley   +1 more source

Novel thalidomide analogues, “me too” drugs and the Brazilian law / Novos análogos da talidomida, medicamentos “me too” e a lei brasileira [PDF]

open access: yes, 2013
In Brazil, thalidomide has been used virtually without interruption since it was launched as a new and revolutionary sedative drug in 1956. After 1965, when its effi cacy to treat erythema nodosum leprosum (ENL) was discovered, it was regarded as an ...
Francisco José Roma Paumgartten
core   +2 more sources

A Simple and Rapid Analytical Method to Detect and Quantify the N‐Nitroso Desmethyl Diltiazem Impurity by Liquid Chromatography‐Tandem Mass Spectrometry in Diltiazem Hydrochloride

open access: yesSEPARATION SCIENCE PLUS, Volume 8, Issue 5, May 2025.
ABSTRACT N‐nitroso desmethyl diltiazem is a known genotoxic impurity in the cardiovascular drug product diltiazem hydrochloride, raising significant concerns due to its potential carcinogenicity. Detection of such impurities at trace levels is crucial to ensure drug safety and regulatory compliance.
Manoj Kumar Mandapaka, Veeraswami Boddu
wiley   +1 more source

Brazilian monitoring programs for pesticide residues in food – Results from 2001 to 2010 [PDF]

open access: yes, 2012
A total of 13,556 samples of 22 fruit and vegetable crops, rice, and beans were analyzed within two Brazilian pesticide residue monitoring programs between 2001 and 2010.
Caldas, Eloisa D., Jardim, Andreia N.O.
core   +1 more source

Exploring the Use of Verjuice for Reduced Sodium Pickle Production: Determination of Hedonic and Rejection Thresholds

open access: yesJournal of Sensory Studies, Volume 40, Issue 2, April 2025.
ABSTRACT Food industry has been searching for strategies to reduce sodium in foods. Verjuice, an acidic juice made from thinned grapes, appears to enhance perceived saltiness in pickles. This study aimed to determine the affective thresholds (Consumer Rejection Threshold: CRT, Compromised Acceptance Threshold: CAT, Hedonic Rejection Threshold: HRT) of ...
Rubia Selmira Lassen   +4 more
wiley   +1 more source

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