Results 111 to 120 of about 2,352,773 (321)

Insecure attachment during infancy predicts greater amygdala volumes in early adulthood [PDF]

, 2014
Background The quality of the early environment is hypothesized to be an influence on morphological development in key neural areas related to affective responding, but direct evidence to support this possibility is limited.
Ahnert, Ainsworth, Baare, Barros-Loscertales, Baur, Bowlby, Brain Development Cooperative Group, Caetano, Caldji, Campbell, Cassidy, Chen, Cox, Dedovic, Erp, Fearon, Fox, Free, Gerritsen, Groh, Gunnar, Halligan, Hertsgaard, Holmes, Huang, Huot, Kaufman, Ladd, Ladouceur, Luby, Lupien, Lupien, MacMaster, MacMillan, Main, McCrory, Meaney, Mehta, Morey, Moutsiana, Munn, Murray, Murray, Murray, Ono, Pannekoek, Qin, Raineki, Rao, Rao, Romanczuk-Seiferth, Rorden, Rosso, Smith, Smith, Spangler, Spitzer, Spitzer, Tottenham, Videbech, Whalen, Wolff, Woolrich   +62 more
core   +2 more sources

Ecologically‐Valid Emotion Signatures Enhance Mood Disorder Diagnostics

Advanced Science, EarlyView.
This study identifies ecologically‐valid Divergent Emotional Functional Networks (DEFN), derived from dynamic functional connectivity during naturalistic movie watching. The DEFN reliably enhances diagnostic accuracy for mood disorders, including major depressive and bipolar disorders, demonstrating strong reproducibility across demographic factors and
Shuyue Xu, Linling Li, Ting Luo, Gan Huang, Li Zhang, Benjamin Becker, Zhen Liang   +6 more
wiley   +1 more source

The DSM‐5 Dimensional Anxiety Scales in a Dutch non‐clinical sample: psychometric properties including the adult separation anxiety disorder scale

International Journal of Methods in Psychiatric Research, 2016
With DSM‐5, the American Psychiatric Association encourages complementing categorical diagnoses with dimensional severity ratings. We therefore examined the psychometric properties of the DSM‐5 Dimensional Anxiety Scales, a set of brief dimensional ...
Eline L Möller, S. Bögels
semanticscholar   +1 more source

Neddylation Targets and Stabilizes NLRP3 to Augment Inflammasome‐Mediated Colitis and Mood Disorder

Advanced Science, EarlyView.
NLRP3 inflammasome contributes to colitis and mood disorder. This study demonstrates that neddylation targets NLRP3 at K287, which hinders its interaction with K48‐linked ubiquitination E3 Trim31 and thereby stabilizes it. Neddylation blockade in myeloid cells and microglia mitigates DSS‐induced colitis and psychological stress‐induced anxiety‐like ...
Wenbin Gai, Mengyao Wu, Anbiao Wu, Zhaofei Jing, Zhenjie Ye, Jiayan Jin, Yaolin Zhang, Min Zhao, Genyu Liu, Xu Wang, Xiqin Yang, Jie Dong, Yunlu Xu, Jiyan Zhang   +13 more
wiley   +1 more source

Internet addiction, test anxiety, adult separation anxiety disorder: Is there a connection?

Digital Health
Background and Aim Internet addiction can cause anxiety and depression. Exams and living far from home can cause anxiety as well. This research aimed to explore the correlation between Internet addiction, exam-related anxiety, and adult separation ...
Hadi Hasani, Mahdi Manoochehri, Fatemeh Zarezadeh, Fatemeh Ramezanian, Milad Bazghaleh, Behnaz Alafchi, Amir Mohammad Chekeni   +6 more
doaj   +1 more source

With a little help from FUN FRIENDS young children can overcome anxiety [PDF]

, 2014
This paper highlights resilience as a key concept when working with young children to improve their emotional wellbeing and reduce anxieties. Supporting children aged 4-7 years with anxiety is a significant area of advancement in terms of therapeutic ...
Carlyle, Donna
core  

Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors

Advanced Science, EarlyView.
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon, Kyungchul Noh, Minkyu Hwang, Yoon‐Jung Kim, Unjin Lee, Yeon Joo Ryu, Je‐Kyung Ryu, Sang Beom Jun, Se‐Young Choi, Woo‐Hyun Cho, Sung Joong Lee   +10 more
wiley   +1 more source

A latent class analysis of parental bipolar disorder: examining associations with offspring psychopathology [PDF]

, 2015
Bipolar disorder (BD) is highly heterogeneous, and course variations are associated with patient outcomes. This diagnostic complexity challenges identification of patients in greatest need of intervention.
Freed, Rachel D., Henin, Aude, Nierenberg, Andrew A., Otto, Michael W., Tompson, Martha C.   +4 more
core   +1 more source

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

Advanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang, Zibin Li, Yao Xiao, Ji Bian, Caian He, Chao Liu, Lan Gong, Lin Han, Zhigang Liu, Min Wang   +9 more
wiley   +1 more source

Human brain evolution and the "Neuroevolutionary Time-depth Principle:" Implications for the Reclassification of fear-circuitry-related traits in DSM-V and for studying resilience to warzone-related posttraumatic stress disorder. [PDF]

, 2006
The DSM-III, DSM-IV, DSM-IV-TR and ICD-10 have judiciously minimized discussion of etiologies to distance clinical psychiatry from Freudian psychoanalysis.
Bracha, Dr. H. Stefan
core   +1 more source