Results 91 to 100 of about 3,104,826 (361)

Characteristics and outcomes of individuals screening positive for borderline personality disorder on an adult inpatient psychiatry unit: a cross-sectional study

BMC Psychiatry
Background Outpatient psychotherapies are gold standard interventions for borderline personality disorder (BPD); however, in clinical reality, higher rates of psychiatric hospitalization and more severe symptoms, including suicidality and self-harm ...
Joann J. Chen, Sam A. Mermin, Lucie A. Duffy, Samantha A. Wong, Savannah D. Layfield, Fernando Rodriguez-Villa, Steven E. Gelda, Eliot M. Gelwan, Jane Eisen, Kerry J. Ressler, Lois W. Choi-Kain, Agustin G. Yip   +11 more
doaj   +1 more source

New Therapeutic Targets for Mood Disorders

The Scientific World Journal, 2010
Existing pharmacological treatments for bipolar disorder (BPD) and major depressive disorder (MDD) are often insufficient for many patients. Here we describe a number of targets/compounds that clinical and preclinical studies suggest could result in ...
Rodrigo Machado-Vieira, Giacomo Salvadore, Nancy DiazGranados, Lobna Ibrahim, David Latov, Cristina Wheeler-Castillo, Jacqueline Baumann, Ioline D. Henter, Carlos A. Zarate   +8 more
doaj   +1 more source

Primary Care Prescription Drug Use and Related Actionable Drug‐Gene Interactions in the Danish Population

Clinical and Translational Science, 2020
Pharmacogenetics (PGx) aims to improve drug therapy using the individual patients’ genetic make‐up. Little is known about the potential impact of PGx on the population level, possibly hindering implementation of PGx in clinical care.
Carin Adriana Theodora Catharina Lunenburg, Alexander Sebastian Hauser, Kazi Ishtiak‐Ahmed, Christiane Gasse   +3 more
doaj   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Help from home for depression: A randomised controlled trial comparing internet-delivered cognitive behaviour therapy with bibliotherapy for depression

Internet Interventions, 2017
Major Depressive Disorder (MDD) is a leading cause of the Global Burden of Disease. Cognitive Behavioural Therapy (CBT) is an effective treatment for MDD, but access can be impaired due to numerous barriers.
Jessica Smith, Jill M. Newby, Nicole Burston, Michael J. Murphy, Sarah Michael, Anna Mackenzie, Felicity Kiln, Siobhan A. Loughnan, Kathleen A. O'Moore, Benjamin J. Allard, Alishia D. Williams, Gavin Andrews   +11 more
doaj   +1 more source

Vanillin attenuates the ethanol withdrawal syndrome and ethanol withdrawal induced anxiety by regulating the neurochemical balance [PDF]

, 2022
Lihui Du, Liping Xiao, Chenglin Zou, Jinrong Huang   +3 more
openalex   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick, Nomin Enkhtsetseg, Joseph Sadok, Matheus Mochetti, Annabel Sorby Adams, Jennifer Guo, Cristina Trapaga Hacker, Isabella Gomez Hjerthen, Seungwon Lee, Siddharth Satish, Andrew S. Ham, Justin Hill, Denis Balaban, Kevin Kyle, Rebecca L. Gillani, Marcelo Matiello, Aleksandar Videnovic, Eric C. Klawiter, W. Taylor Kimberly, Farrah J. Mateen   +19 more
wiley   +1 more source

Multimodal prediction of future depressive symptoms in adolescents

BMC Psychiatry
Background Depression rates surge during adolescence. Early identification of youth at increased risk for depression is crucial for timely intervention and, ideally, prevention.
Linshanshan Wang, Ningxuan Zhou, Nigel M. Jaffe, Kristina Pidvirny, Anna O. Tierney, Hadar B. Fisher, Francesca Morfini, Erika E. Forbes, Diego A. Pizzagalli, Tianxi Cai, Christian A. Webb   +10 more
doaj   +1 more source

No evidence for airborne transmission of Toxoplasma gondii in a very high prevalence area in Lancaster County

Pteridines, 2018
Background: Toxoplasma gondii (T. gondii) has been associated with acute food-borne illness, chronic low-grade inflammation, neuropsychiatric conditions and reactivation of chronic latent infection in immunocompetent hosts.
Wadhawan Abhishek, Hill Dolores E., Dagdag Aline, Mohyuddin Hira, Donnelly Patrick, Jones Jeffrey L., Postolache Teodor T.   +6 more
doaj   +1 more source