Results 91 to 100 of about 3,732,219 (359)

Primary Care Prescription Drug Use and Related Actionable Drug‐Gene Interactions in the Danish Population

open access: yesClinical and Translational Science, 2020
Pharmacogenetics (PGx) aims to improve drug therapy using the individual patients’ genetic make‐up. Little is known about the potential impact of PGx on the population level, possibly hindering implementation of PGx in clinical care.
Carin Adriana Theodora Catharina Lunenburg   +3 more
doaj   +1 more source

Emotion regulation difficulties related to depression and anxiety : a network approach to model relations among symptoms, positive reappraisal, and repetitive negative thinking [PDF]

open access: yes, 2019
Frequent repetitive negative thinking and infrequent positive reappraisal use are theorized to increase risk for depression and anxiety. Yet, research has studied these regulatory strategies at the disorder level, ignoring the clinical heterogeneity and ...
Everaert, Jonas, Joormann, Jutta
core   +2 more sources

Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial

open access: yesJournal of Psychopharmacology, 2016
Background: Clinically significant anxiety and depression are common in patients with cancer, and are associated with poor psychiatric and medical outcomes. Historical and recent research suggests a role for psilocybin to treat cancer-related anxiety and
Stephen Ross   +12 more
semanticscholar   +1 more source

The Case of a 28‐Year‐Old Woman With Medically Refractory Focal Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We present the case of a 28‐year‐old right‐handed woman with medically refractory focal epilepsy. Her seizure semiology and electroencephalography (EEG) indicated a seizure onset zone in the right central‐parietal area. However, both MRI and PET scans were unremarkable, showing no focal lesions or areas of altered metabolism.
Rishi Sharma   +5 more
wiley   +1 more source

New Therapeutic Targets for Mood Disorders

open access: yesThe Scientific World Journal, 2010
Existing pharmacological treatments for bipolar disorder (BPD) and major depressive disorder (MDD) are often insufficient for many patients. Here we describe a number of targets/compounds that clinical and preclinical studies suggest could result in ...
Rodrigo Machado-Vieira   +8 more
doaj   +1 more source

The mental health of elite athletes in the United Kingdom [PDF]

open access: yes, 2018
Objectives: The purpose of this study was to investigate the prevalence of signs of anxiety/depression and distress among a sample of elite athletes in the United Kingdom (UK).
Fockett, Ryan, Longstaff, Frances
core   +2 more sources

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein   +7 more
wiley   +1 more source

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund   +3 more
wiley   +1 more source

Characteristics and outcomes of individuals screening positive for borderline personality disorder on an adult inpatient psychiatry unit: a cross-sectional study

open access: yesBMC Psychiatry
Background Outpatient psychotherapies are gold standard interventions for borderline personality disorder (BPD); however, in clinical reality, higher rates of psychiatric hospitalization and more severe symptoms, including suicidality and self-harm ...
Joann J. Chen   +11 more
doaj   +1 more source

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