Results 131 to 140 of about 2,909,438 (364)
We demonstrate that Foxp1± mice, modeling FOXP1 haploinsufficiency, exhibit behavioral deficits, striatal neuroinflammatory changes including altered microglial complexity and synaptic pruning, and markedly reduced Pde10a expression. Pde10a inhibition starting immediately after birth restores Foxp1± behavior, microglial morphology, and pruning ...
Henning Fröhlich+8 more
wiley +1 more source
EFFECTS OF ANXIETY AND MORPHINE ON DISCRIMINATION OF INTENSITIES OF PAINFUL STIMULI [PDF]
Harris E. Hill+3 more
openalex +1 more source
Weight Cycling Deregulates Eating Behavior in Mice via the Induction of Durable Gut Dysbiosis
Weight cycling in Humans is suspected to dysregulate eating behavior. Mice submitted to body weight cycling by alternating western‐type and regular chow diets display increased hedonic appetite when exposed to a palatable diet, reminiscent of binge‐eating episodes.
Mélanie Fouesnard+13 more
wiley +1 more source
MEASUREMENTS RELATED TO PAIN IN NEUROCIRCULATORY ASTHENIA, ANXIETY NEUROSIS, OR EFFORT SYNDROME: LEVELS OF HEAT STIMULUS PERCEIVED AS PAINFUL AND PRODUCING WINCE AND WITHDRAWAL REACTIONS 1 [PDF]
William P. Chapman+2 more
openalex +1 more source
With a little help from FUN FRIENDS young children can overcome anxiety [PDF]
This paper highlights resilience as a key concept when working with young children to improve their emotional wellbeing and reduce anxieties. Supporting children aged 4-7 years with anxiety is a significant area of advancement in terms of therapeutic ...
Carlyle, Donna
core
24p3R is an astrocytic receptor for α‐Syn uptake. When LCN2 is secreted from astrocytes, it binds to its receptor 24p3R in astrocytes and this binding impedes the α‐Syn PFF binding to 24p3R. This in turn inhibits 24p3R‐mediated α‐Syn PFF uptake and reduces the clearance of extracellular α‐Syn by astrocytes, which contributes to α‐Syn spread and ...
Ying‐Ying Jiao+14 more
wiley +1 more source
Conditions of Nervous Anxiety and their Treatment [PDF]
C. Stanford Read
openalex +1 more source
Math anxiety, intrusive thoughts and performance: Exploring the relationship between mathematics anxiety and performance: The role of intrusive thoughts [PDF]
The current study examined the relationship between math anxiety and arithmetic performance by focusing on intrusive thoughts experienced during problem solving. Participants (N = 122) performed two-digit addition problems on a verification task.
Clark-Carter, David+2 more
core
Circardian rhythm disorder (CRD) causes abnormal expression of intestinal Period 2 (Per2) gene, which compromising intestinal barrier integrity and altering the gut microenvironment. Microbiota dysbiosis and aberrant metabolites production drive central inflammation, impair neurogenesis, and promote functional deficits, ultimately facilitating the ...
Huiliang Zhang+16 more
wiley +1 more source
Cardiovascular disease (CVD) and cancer are leading causes of death worldwide, with overlapping risk factors and pathophysiological mechanisms. This review explores shared pathways, including metabolic dysregulation, chronic inflammation, and gut microbiome alterations, highlighting dual‐benefit strategies such as lifestyle modifications and repurposed
Shihan Xiang+6 more
wiley +1 more source