Results 101 to 110 of about 3,831,493 (359)
DeckerMed Transitional Year Weekly Curriculum™, 2017 Anxiety disorders are the most common psychiatric disorders among adults in the United States. Although anxiety disorders generally result in significant psychosocial impairment, most adults do not seek treatment until many years after the onset of the anxiety disorder.
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Advanced Science, EarlyView.Ma et al. report the hippocampal and hepatic acetylcholine (ACh) levels are differently modulated by regular versus irregular exercise, which contributes to coordinate hippocampal astrocyte activity and hepatic FBXL6high neutrophil recruitment. This ACh‐modulated brain‐liver circuit links the effects of exercise on fear memory extinction and liver ...
Pengjiao Ma +10 more
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Social Anxiety Disorder and Mood Disorders Comorbidity [PDF]
Psikiyatride Güncel Yaklaşımlar, 2012 Social Anxiety Disorder is a common disorder leading functional impairment. The comorbidity between mood disorders with social anxiety disorder is relatively common. This comorbidity impacts the clinical severity, resistance and functionality of patients.
Zerrin Binbay, Ahmet Koyuncu
doaj
Advanced Science, EarlyView.This study reveals that early rather than late administration of S‐ketamine can ameliorate PTSD symptoms. This phenomenon is attributed to reversing the progressive inhibition of VTADA neurons and the function of VTADA‐OFC circuit following stress. Targeted stimulation of the OFC by TI‐NIBS to enhance DA release effectively extends the therapeutic time
Ye Wang +20 more
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American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023 Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei +4 more
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Advanced Science, EarlyView.Circardian rhythm disorder (CRD) causes abnormal expression of intestinal Period 2 (Per2) gene, which compromising intestinal barrier integrity and altering the gut microenvironment. Microbiota dysbiosis and aberrant metabolites production drive central inflammation, impair neurogenesis, and promote functional deficits, ultimately facilitating the ...
Huiliang Zhang +16 more
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Biology of anxiety disorders. Rudolph Hoehn Saric, M.D., and Daniel R. McLeod, PhD. American Psychiatric Press, Inc., Washington D.C., 1993, 259 pp, $36.00 [PDF]
, 1994 James L. Abelson
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A brief measure for assessing generalized anxiety disorder: the GAD-7.
Archives of Internal Medicine, 2006 R. Spitzer +3 more
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Advanced Science, EarlyView.FOXQ1 emerges as a master transcriptional regulator of brain endothelial metabolism, orchestrating mitochondrial function through dual control of calcium signaling and cristae organization. This study reveals that brain endothelial cells rely on oxidative phosphorylation rather than glycolysis alone, challenging the current metabolic paradigm and ...
Wenzheng Zou +8 more
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A Replicable and Generalizable Neuroimaging‐Based Indicator of Pain Sensitivity Across Individuals
Advanced Science, EarlyView.Humans differ in their sensitivity to pain. With six large and diverse fMRI datasets (total N = 1046), this study finds that such individual differences in pain sensitivity can be tracked by fMRI responses to painful stimuli. A highly generalizable machine learning model is further built to predict pain sensitivity across all datasets and analgesic ...
Li‐Bo Zhang +7 more
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