Results 101 to 110 of about 4,281,144 (339)

Machine Learning to Detect Anxiety Disorders from Error-Related Negativity and EEG Signals [PDF]

open access: yesarXiv
Anxiety is a common mental health condition characterised by excessive worry, fear and apprehension about everyday situations. Even with significant progress over the past few years, predicting anxiety from electroencephalographic (EEG) signals, specifically using error-related negativity (ERN), still remains challenging. Following the PRISMA protocol,
arxiv  

Targeting Senescence with Apigenin Improves Chemotherapeutic Efficacy and Ameliorates Age‐Related Conditions in Mice

open access: yesAdvanced Science, EarlyView.
As a plant‐derived flavonoid, apigenin directly targets PRDX6 to inhibit its PLA2 activity, blocking HSPA8 activation and disturbing its interactions with ATM and p38MAPK in senescent cells. By dampening wide spectrum expression of the SASP, apigenin prevents loss of tissue homeostasis, improves organ function, and alleviates multiple age‐related ...
Hongwei Zhang   +10 more
wiley   +1 more source

Are Anxiety Detection Models Generalizable? A Cross-Activity and Cross-Population Study Using Wearables [PDF]

open access: yesarXiv
Anxiety-provoking activities, such as public speaking, can trigger heightened anxiety responses in individuals with anxiety disorders. Recent research suggests that physiological signals, including electrocardiogram (ECG) and electrodermal activity (EDA), collected via wearable devices, can be used to detect anxiety in such contexts through machine ...
arxiv  

Medium Spiny Neurons Mediate Timing Perception in Coordination with Prefrontal Neurons in Primates

open access: yesAdvanced Science, Volume 12, Issue 16, April 24, 2025.
Timing perception is a crucial cognitive function enabling effective navigation in the environment, involving both prospective and retrospective timing. This study investigates the neural mechanisms in monkeys, uncovering distinct processes that shape temporal perception and highlighting the essential role of D2 medium spiny neurons in the striatum as ...
Xinhe Liu   +4 more
wiley   +1 more source

Usage of Virtual Reality in Combating Social Anxiety Disorders in Non-native English Speakers: A Survey [PDF]

open access: yesarXiv
Social Anxiety Disorder (SAD) is a common yet underestimated mental health disorder. While non-native English speaker (NNES) students face public speaking, they are more likely to suffer some public speaking anxiety (PSA) due to linguistic and sociocultural differences \cite{cite1}.
arxiv  

Advances in Fecal Microbiota Transplantation for Gut Dysbiosis‐Related Diseases

open access: yesAdvanced Science, Volume 12, Issue 13, April 3, 2025.
This article reviews the use of fecal microbiota transplantation (FMT) to treat intestinal diseases like recurrent Clostridioides difficile infection (rCDI), inflammatory bowel disease (IBD), and irritable bowel syndrome (IBS). It discusses FMT's efficacy, influencing factors such as donor selection, recipient characteristics, and treatment protocols ...
Shuna Hou   +4 more
wiley   +1 more source

Autism and mild epilepsy associated with a de novo missense pathogenic variant in the GTPase effector domain of DNM1

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView., 2023
Abstract Dynamin 1 is a GTPase protein involved in synaptic vesicle fission, which facilitates the exocytosis of neurotransmitters necessary for normal signaling. Pathogenic variants in the DNM1 gene are associated with intractable epilepsy, often manifested as infantile spasms at onset, developmental delay, and a movement disorder, and are located in ...
Davide Mei   +4 more
wiley   +1 more source

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