Results 171 to 180 of about 1,037,362 (313)

Enhanced Protein Synthesis and Hippocampus‐Dependent Memory via Inhibition of YTHDF2‐Mediated m6A mRNA Degradation

Advanced Science, EarlyView.
YTHDF2‐mediated m6A mRNA decay critically regulates learning and memory. Its forebrain‐specific knockout in mice impedes degradation of m6A‐modified mRNAs, enhancing hippocampal synaptic transmission, protein synthesis, and memory. Conversely, hippocampal YTHDF2 reintroduction or SEMA4B reduction reverses this enhancement, while its overexpression ...
Kuan Li, Chen Guo, Xiaoli Wu, Cuiting Wu, Songfen Wu, Si Su, Min Wu, Xidan Zhou, Si Li, Yihui Cui, Tao Zhou   +10 more
wiley   +1 more source

Microglial Rack1 Deficiency Alleviates Alzheimer's Disease Pathology through Enhancing IGF1‐Mediated Astrocytic Phagocytosis

Advanced Science, EarlyView.
Alzheimer's disease (AD) is the most common neurodegenerative disorder. This study demonstrates that microglial Rack1 deficiency decreased Aβ deposition and neuroinflammation and ameliorated cognitive impairments in AD model mice by enhancing IGF1‐mediated astrocytic phagocytosis.
Jingdan Zhang, Yanling He, Pin Yang, Hengchang Zhang, Yueyang Tong, Lingling Jiang, Zehan Li, Meichen Yan, Xiaoheng Li, Qinghu Yang, Jing Yang, Zengqiang Yuan, Jiyan Zhang, Jinbo Cheng   +13 more
wiley   +1 more source

Efficacy of acupuncture for generalized anxiety disorder: a systematic review. [PDF]

Ann Gen Psychiatry
Lai J, Wang Y, Yao X, Yu J, Lu S, Lu J, Liu J.   +6 more
europepmc   +1 more source

Osteoclast‐Derived SLIT3 Mediates Osteoarthritis Pain and Degenerative Changes

Advanced Science, EarlyView.
In TMJ‐OA, osteoclasts play a significant role in promoting the growth of sensory nerves at the osteochondral interface. In early OA, TRAP+ osteoclast‐derived SLIT3 induces sensory nerve growth into the condylar cartilage. This nerve growth facilitates the development of pain associated with OA.
Weiwei Zhu, Wenpin Qin, Jialu Gao, Yihan Guo, Xiaoxiao Han, Zhangyu Ma, Xiaokang Zhang, Jie He, Jing Liu, Bo Gao, Changjun Li, Lina Niu, Jianfei Yan, Kai Jiao   +13 more
wiley   +1 more source

Parkinson's Disease as Illness Anxiety Disorder: A Rare Case Report. [PDF]

Clin Case Rep
Fatahi R, Khooshab MS, Sadatakhavi SF, Ziyaei A, Bidaki R.   +4 more
europepmc   +1 more source

Slowed extinction of repetitive threat-neutralization behavior in anxiety-related disorders: Effects from a novel fear-conditioning paradigm

Riley Rozniarek, Annette Rostel, A. F. Robinson, Ryan Smith, Martin P Paulus, Robin L. Aupperle, Hannah Berg   +6 more
openalex   +1 more source

Highly Stabilized Ni‐Rich Cathodes Enabled by Artificially Reversing Naturally‐Formed Interface

Advanced Energy Materials, Volume 15, Issue 11, March 18, 2025.
The application of Ni‐rich cathode materials is obstructed by interfacial and structural instability. This work proposes a facile and cost‐effective Al‐based vapor‐phase surface reaction strategy on Ni‐rich cathode to maintain its structural integrity from near‐surface to bulk.
Jinjin Ma, Yipeng Sun, Duojie Wu, Changhong Wang, Ruizhi Yu, Hui Duan, Matthew Zheng, Ruying Li, M. Danny Gu, Yang Zhao, Jigang Zhou, Xueliang Sun   +11 more
wiley   +1 more source

Interleukin-40 and Oxidative Stress in Patients With Generalized Anxiety Disorder. [PDF]

Psychiatry Investig
Fedai ÜA, Çetin SB, Koyuncu İ, Akıl Ö.   +3 more
europepmc   +1 more source

Anxiety Disorders and Adolescent School Aversion: An Analysis of the Phenomenon in Chinese Mainland and Intervention Approaches [PDF]

Li Zhang
openalex   +1 more source

Research Progress on Idebenone in Neurodegenerative Diseases

AGING MEDICINE, EarlyView.
The study not only summarizes the biological properties of Idebenone (IDE), including its role in improving mitochondrial function and antioxidative stress, but also explores its clinical research progress in various neurodegenerative diseases, providing a new perspective for the treatment of these disorders.
Yanqing Zhang, Yanhong Ren, Xiaoran Zhu, Tianhao Liu, Rundong Han, Yuqing Fang, Zhangning Zhao, Fei Mao, Yalin Wang, Xian Li, Xiuhua Li   +10 more
wiley   +1 more source