Results 1 to 10 of about 163,561 (303)

Benzodiazepine anti-anxiety agents: prevalence and correlates of use in a southern community. [PDF]

American Journal of Public Health, 1991
BACKGROUND: Benzodiazepine anti-anxiety agents are the most widely prescribed psychotherapeutic drugs in the United States today. Recent evidence, however, suggests that their use may be decreasing. METHODS: We examine the population prevalence and correlates of use of benzodiazepine anxiolytics at the Duke site of the NIMH-sponsored Epidemiologic ...
R Landerman, L K George
exaly   +3 more sources

Peripheral Anti-nociceptive and Anti-inflammatory Effect of OleanoliAcid in a Rat Model of Osteoarthritis [PDF]

, 2021
Background: Oleanolic acid (OA) is a naturally occurring pentacyclic triterpenoid with multifarious actions. The anti-inflammatory effect it exerts when taken orally is the most important; however, the underpinning mechanisms of such effects have not yet
Fouani, Malak, Fakhoury, Marc, Salman, Israa, Lawand, Nada Bashir   +3 more
core   +1 more source

Design, Synthesis and Biological Evaluation of a Novel Series of Thiadiazole-Based Anticancer Agents as Potent Angiogenesis Inhibitors

, 2021
Background: Thiadiazole has attracted a great deal of interest as a versatile heterocycle for the discovery and development of potent anticancer agents. Thiadiazole derivatives exert potent antitumor activity against a variety of human cancer cell lines ...
Turan, Gulhan, Gülhan Turan, KAPLANCIKLI, ZAFER ASIM, ALTUĞ, BURCUGÜL, Ali S. Koparal, KOPARAL, ALİ SAVAŞ, Ayşe T. Koparal, Burcugül Altuğ-Tasa, Betül Kaya-Çavuşoğlu, Zafer A. Kaplancıklı, Kaya-cavusoglu, Betul   +10 more
core   +1 more source

Selective serotonin reuptake inhibitors in the treatment of generalized anxiety disorder [PDF]

, 2002
Selective serotonin reuptake inhibitors have proven efficacy in the treatment of panic disorder, obsessive–compulsive disorder, post-traumatic stress disorder and social anxiety disorder.
Buis, C., Mayers, A.G., Baldwin, D.S.
core   +1 more source

Synthesis, Molecular Docking and In Vivo Biological Evaluation of Iminostilbene Linked 1,2,3-Triazole Pharmacophores as Promising Anti-Anxiety and Anti-Inflammatory Agents

, 2022
Background: Iminostilbene and 1,2,3-triazole ring containing compounds are considered as beneficial substrates in drug design. Objectives: This study was aimed at the synthesis of novel series of iminostilbene linked 1,2,3triazole pharmacophores (7c-n ...
Shalavadi, Mallappa, Rangaswamy, J., Ankali, K. N., Naik, Nagaraja   +3 more
core   +1 more source

Behavioral Profiles of Genetically Selected Aggressive and Nonaggressive Male Wild House Mice in Two Anxiety Tests [PDF]

, 2000
Artificially selected aggressive (SAL) and non-aggressive (LAL) male house mice were tested in a hexagonal tunnel maze and light–dark preference (LD) box to determine if the bidirectional selection for aggressive behavior leads to a coselection for ...
Sluyter, Frans, Hogg, Sandy, Hof, Marleen, Steimer, Thierry, de Ruiter, Anne, Würbel, Hanno, Hogg, Sandy,, Sluyter, Frans,, Koolhaas, Jaap, Hof, Maleen,, Koolhaas, Jaap,, Steimer, Thierry,, Würbel, Hanno,, Ruiter, Anne de,   +13 more
core   +1 more source

Anti-influenza agents from Traditional Chinese Medicine

, 2010
After new human transmissible H1N1 (swine flu) viruses were reported in Mexico and the United States in April 2009, the World Health Organization (WHO) announced the emergence of a novel influenza A virus.
Jiaju Zhou, Zirong Yang, Zhou, Jiaju, Pei-Gen Xiao, Qiong Gu, Wang, Yi-Fei, Wang, YF, Jun Xu, Ge, Hu, Hua Su, Xu, Jun, Gu, Qiong, Yang, Zirong, Hai-Bo Liu, Su, Hua, Liu, Hai-Bo, Xiao, Pei-Gen, Liu, Yanhuai, Hu Ge, Yanhuai Liu, Yi-Fei Wang   +20 more
core   +1 more source

Models of anxiety for agent deliberation : the benefits of anxiety-sensitive agents blue sky ideas track

, 2023
Anxiety is one of the most critical sources of harm to psychological wellbeing, tied to an array of issues, from discomfort and maladaptive coping to severe pathological disorders -making of anxiety one of the largest economic and social healthcare ...
Vanhée, Loïs,, Horned, Arvid,
core  

Identification of phytoconstituents of Tragia involucrata leaf extracts and evaluate their correlation with anti-inflammatory & antioxidant properties.

, 2021
AimsThe present investigation was aimed at exploring the phytoconstituents using Gas Chromatography Mass Spectroscopy and to evaluate antioxidant and anti-inflammatory properties of the leaf extracts.Materials and methodsThe extracts were obtained ...
Dua, K, Chellappan, DK, Velu, V, Radhakrishnan, V, Malipeddi, H, Kumar, N, Mehta, M, Fuloria, S, Gupta, G, Banerjee, S   +9 more
core   +1 more source

Evaluation of the Effectiveness and Use of Anti-Methicillin-Resistant Staphylococcus aureus Agents for Aspiration Pneumonia in Older Patients Using a Nationwide Japanese Administrative Database [PDF]

, 2023
Studies indicated potential harm from empirical broad-spectrum therapy. A recent study of hospitalizations for community-acquired pneumonia suggested that empirical anti-methicillin-resistant Staphylococcus aureus (MRSA) therapy was associated with an ...
Kei Tokutsu, Fujino, Yoshihisa, Yura, Hirokazu, Iwanaga, Naoki, Yuya Ito, Naoki Iwanaga, Daisuke Okuno, Shinya Matsuda, Takashi Kido, Takeda, Kazuaki, Koichi Izumikawa, Yanagihara, Katsunori, Takatomo Tokito, Kazuhiro Yatera, Matsuda, Shinya, Ishimoto, Hiroshi, Katsunori Yanagihara, Sakamoto, Noriho, Fushimi, Kiyohide, Ito, Yuya, Satoru Koga, Tokito, Takatomo, Takahiro Takazono, Hirokazu Yura, Hiroshi Ishimoto, Koga, Satoru, Noriho Sakamoto, Yoshihisa Fujino, Hiroshi Mukae, Muramatsu, Keiji, Kazuaki Takeda, Yatera, Kazuhiro, Okuno, Daisuke, Kido, Takashi, Tokutsu, Kei, Takazono, Takahiro, Keiji Muramatsu, Mukae, Hiroshi, Izumikawa, Koichi, Kiyohide Fushimi   +39 more
core   +1 more source