Results 11 to 20 of about 4,267,776 (295)

Psychotropic and anti-epileptic drug use, before and after surgery, among patients with low-grade glioma: a nationwide matched cohort study

BMC Cancer, 2021
Background Low-grade glioma (LGG) is a relatively rare type of brain tumour. The use of antidepressant, sedative and anti-epileptic drugs can reflect the burden of the disease.
Isabelle Rydén, Erik Thurin, Louise Carstam, Anja Smits, Sasha Gulati, Roger Henriksson, Øyvind Salvesen, Asgeir Store Jakola   +7 more
doaj   +1 more source

A facial expression for anxiety [PDF]

, 2012
Anxiety and fear are often confounded in discussions of human emotions. However, studies of rodent defensive reactions under naturalistic conditions suggest anxiety is functionally distinct from fear. Unambiguous threats, such as predators, elicit flight
Inchley-Mort, Sophie L, Burgess, Adrian P, Pickering, Alan D., Burgess, Adrian P., Perkins, Adam M.; id_orcid, Inchley-Mort, Sophie L., Perkins, Adam M., Corr, Philip J., Perkins, Adam M, Corr, Philip J, Pickering, Alan   +10 more
core   +1 more source

Anti-interleukin-13 and anti-interleukin-4 agents versus placebo, anti-interleukin-5 or anti-immunoglobulin-E agents, for children and adults with asthma [PDF]

, 2018
This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the efficacy and safety of anti-interleukin-13 or anti-interleukin-4 agents, compared with placebo, anti-Immunoglobulin E agents, or anti-interleukin-5 ...
Evans, David John William, Drew, Stewart, Edwards, Michaela Jane, Gallagher, A., Vyas, Aashish, Nair, Parameswaran, Sharma, R, Marsden, Paul   +7 more
core   +3 more sources

Synthesis, Molecular Docking and In Vivo Biological Evaluation of Iminostilbene Linked 1,2,3-Triazole Pharmacophores as Promising Anti-Anxiety and Anti-Inflammatory Agents

, 2022
Background: Iminostilbene and 1,2,3-triazole ring containing compounds are considered as beneficial substrates in drug design. Objectives: This study was aimed at the synthesis of novel series of iminostilbene linked 1,2,3triazole pharmacophores (7c-n ...
Shalavadi, Mallappa, Rangaswamy, J., Ankali, K. N., Naik, Nagaraja, Kariyappa N. Ankali, Nagaraja Naik, Javarappa Rangaswamy, Mallappa Shalavadi   +7 more
core   +1 more source

Comparison of Oral Midazolam and Promethazine with Oral Midazolam alone for Sedating Children during Computed Tomography

Archives of Academic Emergency Medicine, 2018
Introduction: Both midazolam and promethazine are recommended to be used as sedatives in many studies but each have some side effects that limits their use. Combination therapy as an alternative method, may decreases these limitations.
Hassan Barzegari, Behzad Zohrevandi, Kambiz Masoumi, Arash Forouzan, Ali Asgari Darian, Shaqayeq Khosravi   +5 more
doaj   +1 more source

Comparing the Sedative Effects of Intranasal Dexmedetomidine, Midazolam, and Ketamine in Outpatient Pediatric Surgeries: A Randomized Clinical Trial [PDF]

Iranian Journal of Medical Sciences
Background: The management of preoperative anxiety in pediatric patients, as well as its implications, has remained challenging for anesthesiologists.
Simin Azemati, Maryam Keihani, Mohammad Ali Sahmeddini, Fatemeh Kanaani Nejad, Laleh Dehghanpisheh, Mohammad Bagher Khosravi, Naeimehossadat Asmarian   +6 more
doaj   +1 more source

Ultrasound-Assisted Ugi-Azide Multicomponent Reaction for the Synthesis of 1,5-Disubstituted Tetrazoles

Chemistry Proceedings, 2023
The Ugi-azide MCR (UA) is one of the most efficient methods for the synthesis of 1,5-disubstituted-1H-tetrazoles (1,5-DS-T). Complex drug-like scaffolds incorporating tetrazoles have demonstrated a wide range of therapeutic benefits such as anti ...
Alejandro Corona-Díaz, Sandra C. Ramírez-López, David Calderón-Rangel, Cristian Saldaña-Arredondo, Rocío Gámez-Montaño   +4 more
doaj   +1 more source

Path analysis examining relationships among antecedents of anxiety, multidimensional state anxiety, and triathlon performance [PDF]

, 1995
The official published version of this article can be found at the link below. This is a authors’ draft of the paper: Copyright @ Perceptual and Motor Skills, 1995The study explored predictive paths for antecedents of anxiety, state anxiety responses,
Lane, AM, Peter C. Terry, Andrew M. Lane, Costas I. Karageorghis, Terry, PC, Karageorghis, CI   +5 more
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Recent Advancement in Drug Design and Discovery of Pyrazole Biomolecules as Cancer and Inflammation Therapeutics

Molecules, 2022
Pyrazole, an important pharmacophore and a privileged scaffold of immense significance, is a five-membered heterocyclic moiety with an extensive therapeutic profile, viz., anti-inflammatory, anti-microbial, anti-anxiety, anticancer, analgesic ...
Md. Jahangir Alam, Ozair Alam, Mohd. Javed Naim, Farah Nawaz, Ajay Manaithiya, Mohd Imran, Hamdy Khamees Thabet, Sultan Alshehri, Mohammed M. Ghoneim, Prawez Alam, Faiyaz Shakeel   +10 more
doaj   +1 more source

Evaluation of the Effectiveness and Use of Anti-Methicillin-Resistant Staphylococcus aureus Agents for Aspiration Pneumonia in Older Patients Using a Nationwide Japanese Administrative Database [PDF]

, 2023
Studies indicated potential harm from empirical broad-spectrum therapy. A recent study of hospitalizations for community-acquired pneumonia suggested that empirical anti-methicillin-resistant Staphylococcus aureus (MRSA) therapy was associated with an ...
Kei Tokutsu, Fujino, Yoshihisa, Yura, Hirokazu, Iwanaga, Naoki, Yuya Ito, Naoki Iwanaga, Daisuke Okuno, Shinya Matsuda, Takashi Kido, Takeda, Kazuaki, Koichi Izumikawa, Yanagihara, Katsunori, Takatomo Tokito, Kazuhiro Yatera, Matsuda, Shinya, Ishimoto, Hiroshi, Katsunori Yanagihara, Sakamoto, Noriho, Fushimi, Kiyohide, Ito, Yuya, Satoru Koga, Tokito, Takatomo, Takahiro Takazono, Hirokazu Yura, Hiroshi Ishimoto, Koga, Satoru, Noriho Sakamoto, Yoshihisa Fujino, Hiroshi Mukae, Muramatsu, Keiji, Kazuaki Takeda, Yatera, Kazuhiro, Okuno, Daisuke, Kido, Takashi, Tokutsu, Kei, Takazono, Takahiro, Keiji Muramatsu, Mukae, Hiroshi, Izumikawa, Koichi, Kiyohide Fushimi   +39 more
core   +1 more source