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The development of clinical practice guidelines for social anxiety disorder began in March 2018 when the Joint Clinical Practice Guideline Development Committee for Anxiety and Obsessive–Compulsive Disorders was formed by the Japanese Society of Anxiety ...
Satoshi Asakura+7 more
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Neurobiology of the Orexin System and Its Potential Role in the Regulation of Hedonic Tone
Orexin peptides comprise two neuropeptides, orexin A and orexin B, that bind two G-protein coupled receptors (GPCRs), orexin receptor 1 (OXR1) and orexin receptor 2 (OXR2).
Martin A. Katzman, Matthew P. Katzman
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BackgroundCOVID-19 outbreak have a long-term negative impact on mental health. Meanwhile, it may also provide opportunities for positive outcomes (e.g., post-traumatic growth).
Jingchu Hu+6 more
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Repeated excessive alcohol consumption is a risk factor for alcohol use disorder (AUD). Although AUD has been more common in men than women, women develop more severe behavioral and physical impairments. However, relatively few new therapeutics targeting
Sharvari Narendra+10 more
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Mentalizing Bodies: Explicit Mentalizing Without Words in Psychotherapy
Introduction: Mentalization concerns the human ability to understand the actions of others (and oneself) in terms of intentional mental states. Theoretically, the notion has been described via the poles of automatic, non-verbal implicit mentalization as ...
Thomas Wiben Jensen+3 more
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The amygdala, a key target for chronic stress, forms the hub of the brain’s emotional circuits with the medial prefrontal cortex (mPFC) and ventral hippocampus (vHPC).
Yuan-Pei Zhang+4 more
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Neuroimaging in anxiety disorders [PDF]
Neuroimaging studies have gained increasing importance in validating neurobiological network hypotheses for anxiety disorders. Functional imaging procedures and radioligand binding studies in healthy subjects and in patients with anxiety disorders provide growing evidence of the existence of a complex anxiety network, including limbic, brainstem ...
Engel, Kirsten+3 more
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IntroductionCOVID-19 related stress might vary with the pandemic changes, as well as other associated factors. This study aimed to compare the stress level during the first wave of the pandemic outbreak and 1 year later in China, and to explore the ...
Jingchu Hu+10 more
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Post-synaptic specialization is critical to the neurotransmitter release and action potential conduction. The neuromuscular junctions (NMJs) are the synapses between the motor neurons and muscle cells and have a more specialized post-synaptic membrane ...
Suqi Zou, Bing-Xing Pan
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Exposure to single prolonged stress fails to induce anxiety-like behavior in mice
Single prolonged stress (SPS) is a well-established and most frequently used rat model to induce post-traumatic stress disorder (PTSD)-like symptoms, which helps to understand the neurobiological mechanisms as well as developing novel therapeutic ...
Wen-Jie You+6 more
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