Results 41 to 50 of about 1,196,037 (307)

Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons, Todd Levine, Charles H. Adler, Bailey Bellaire, Ningshan Wang, Pinky Agarwal, Georgina M. Aldridge, Alexandru Barboi, Daniel Claassen, Virgilio G. H. Evidente, Douglas Galasko, Alejandra Gonzalez‐Duarte, Ramon Gil, Mark Gudesblatt, Stuart H. Isaacson, Horacio Kaufmann, Pravin Khemani, Rajeev Kumar, Guillaume Lamotte, Andy J. Liu, Nikolaus R. McFarland, Mitchell G. Miglis, Adam Reynolds, Gregory A. Sahagian, Marie‐Helene Saint‐Hilaire, Julie B. Schwartzbard, Wolfgang Singer, Michael J. Soileau, Steven Vernino, Patricio Millar Vernetti, Oleg Yerstein, Roy Freeman   +31 more
wiley   +1 more source

Trauma-related intrusive memories and anterior hippocampus structural covariance: an ecological momentary assessment study in posttraumatic stress disorder

Translational Psychiatry
Trauma-related intrusive memories (TR-IMs) are hallmark symptoms of posttraumatic stress disorder (PTSD), but their neural correlates remain partly unknown.
Quentin Devignes, Boyu Ren, Kevin J. Clancy, Kristin Howell, Yara Pollmann, Lucia Martinez-Sanchez, Courtney Beard, Poornima Kumar, Isabelle M. Rosso   +8 more
doaj   +1 more source

Circulating PACAP levels are associated with altered imaging measures of entorhinal cortex neurite density in posttraumatic stress disorder

European Journal of Psychotraumatology
Introduction: Pituitary adenylate cyclase-activating polypeptide (PACAP) regulates plasticity in brain systems underlying arousal and memory and is associated with posttraumatic stress disorder (PTSD).
Steven J. Granger, Victor May, Sayamwong E. Hammack, Eylül Akman, Sydney A. Jobson, Elizabeth A. Olson, Cameron D. Pernia, Nikos P. Daskalakis, Caitlin Ravichandran, William A. Carlezon, Kerry J. Ressler, Scott L. Rauch, Isabelle M. Rosso   +12 more
doaj   +1 more source

New Therapeutic Targets for Mood Disorders

The Scientific World Journal, 2010
Existing pharmacological treatments for bipolar disorder (BPD) and major depressive disorder (MDD) are often insufficient for many patients. Here we describe a number of targets/compounds that clinical and preclinical studies suggest could result in ...
Rodrigo Machado-Vieira, Giacomo Salvadore, Nancy DiazGranados, Lobna Ibrahim, David Latov, Cristina Wheeler-Castillo, Jacqueline Baumann, Ioline D. Henter, Carlos A. Zarate   +8 more
doaj   +1 more source

A pilot exploration of ADHD symptoms in hoarding disorder: Co-occurring disorders or part of the hoarding syndrome?

Journal of Affective Disorders Reports, 2023
Background: Symptoms of ADHD are common in individuals with hoarding disorder (HD). It remains unclear whether these attentional symptoms reflect high co-occurrence rates of ADHD and HD, or whether inattentive symptoms can be conceptualized as intrinsic ...
Blaise L. Worden, David F. Tolin
doaj   +1 more source

Attention bias dynamics and symptom severity during and following CBT for social anxiety disorder [PDF]

, 2016
Objective: Threat-related attention bias figures prominently in contemporary accounts of the maintenance of anxiety disorders, yet longitudinal intervention research relating attention bias to anxiety symptom severity is limited.
Beevers, CG, Bernstein, A, Davis, ML, Koster, Ernst, Reinecke, A, Rosenfield, D, Smits, JAJ, Zvielli, A   +7 more
core   +2 more sources

Remote Monitoring in Myasthenia Gravis: Exploring Symptom Variability

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare, autoimmune disorder characterized by fluctuating muscle weakness and potential life‐threatening crises. While continuous specialized care is essential, access barriers often delay timely interventions. To address this, we developed MyaLink, a telemedical platform for MG patients.
Maike Stein, Maximilian Mönch, Meret Herdick, Frauke Stascheit, Sarah Hoffmann, Hannah Preßler, Philipp Mergenthaler, Carla Dusemund, Paolo Doksani, Haoqi Sun, Pushpa Narayanaswami, Andreas Meisel, Lea Gerischer, Sophie Lehnerer   +13 more
wiley   +1 more source

The impact of father–son relationship on suicidal ideation in Chinese gay and bisexual men: the mediating role of masculinity and self-esteem

BMC Psychology
Background In China, gay and bisexual men exhibit higher levels of suicidal ideation than their heterosexual counterparts do. The influence of the father–son relationship on mental health within this group remains understudied. This study aims to explore
Yiting Huang, Junhao Liang, Gang Huang, Jiarui Liu, Dejia Zhu, Jiayu Liu, Jingchu Hu   +6 more
doaj   +1 more source

Emergency care provision for, and psychological distress in, survivors of domestic violence

South African Family Practice, 2007
Background: This study aimed (i) to ascertain the number of treatment referrals and information about protection orders given to survivors of domestic violence presenting for emergency trauma care, as reported at the one-month visit, (ii) to obtain a ...
Kate Joyner, Lennette Theunissen, Liezel de Villiers, Sharain Suliman, Timothy Hardcastle, Soraya Seedat   +5 more
doaj   +1 more source

Alcohol, Anxiety, and Depressive Disorders. [PDF]

, 1996
Alcoholics frequently experience episodes of intense depression and/or severe anxiety. Depressed or anxious alcohol-dependent people often believe that they drink to relieve symptoms of sadness or nervousness.
Schuckit, Marc A
core