Results 51 to 60 of about 2,496,713 (305)

Evidence-based pharmacological treatment of anxiety disorders, post-traumatic stress disorder and obsessive-compulsive disorder: a revision of the 2005 guidelines from the British Association for Psychopharmacology [PDF]

, 2014
This revision of the 2005 British Association for Psychopharmacology guidelines for the evidence-based pharmacological treatment of anxiety disorders provides an update on key steps in diagnosis and clinical management, including recognition, acute ...
den Boer, J.A., Fineberg, N.A., Bandelow, B., Davies, S., Nutt, David J, Wee, N. van der, Fineberg, Naomi, Scott, Jan, O'Neill, C., Anderson, I.M., Nutt, D.J., O’Neill, C., Scott, J., Allgulander, Christer, Christmas, D.M., Christmas, David M, Fineberg, N., Davies, Simon, Allgulander, C., Anderson, Ian M., McCrone, P., Wittchen, H-U, Christmas, David M., van der Wee, N., Anderson, Ian M, Malizia, A., Nutt, David J., O'Neill, Catherine, Baldwin, D.S., Lidbetter, N., Lidbetter, Nicky, Bandelow, Borwin, Nabarro, Daniel, Malizia, Andrea, McCrone, Paul, van der Wee, Nic, Wittchen, Hans-Ulrich, Baldwin, David S., Baldwin, David S, den Boer, Johan A, Nabarro, D., Boer, J.A. den, Wittchen, H.U., Fineberg, Naomi A., den Boer, Johan A., Baldwin, DS, Nutt, DJ, Lidbetter, N, O’Neill, Catherine, Bandelow, B, den, Boer JA, Anderson, IM, Fineberg, N, Allgulander, C,, Davies, S, Christmas, DM   +55 more
core   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Emotional intensity and visual imagery in trauma nightmares map to posterior hippocampus connectivity

Translational Psychiatry
Distressing dreams or nightmares about a traumatic experience are common among trauma-exposed individuals and contribute to the maintenance of posttraumatic stress disorder (PTSD) symptoms.
Meaghan McKenna, Kevin J. Clancy, Christine J. So, Yara Pollmann, Boyu Ren, Isabelle M. Rosso   +5 more
doaj   +1 more source

Protocol for the Parent Anxiety Transmission and Habits (PATH) study: a randomised controlled trial testing parent interpretation bias as a key mechanism of intergenerational transmission of anxiety

BMJ Open
Introduction Anxiety disorders are the most common youth mental health problems in the USA. Most children do not receive treatment and among the few who do, many do not experience significant improvement.
Margaret A Chiffer, Daniel P Dickstein, Roni Itkin-Ofer, Jennie M Kuckertz, Boyu Ren, Doah E Shin, Alexandra L Silverman, Christian A Webb, Courtney Beard   +8 more
doaj   +1 more source

The effects of perinatal bisphenol A exposure on thyroid hormone homeostasis and glucose metabolism in the prefrontal cortex and hippocampus of rats

Brain and Behavior, 2019
Introduction Bisphenol A (BPA) is an endocrine disruptor widely used to manufacture consumer goods. Although the thyroid hormone (TH) disrupting potential of BPA has been thought to be responsible for the neuropsychiatric deficits in the animals that ...
Xiaobin Xu, Shijun Fan, Yuanqiao Guo, Ruei Tan, Junyu Zhang, Wenhua Zhang, Bing‐Xing Pan, Nobumasa Kato   +7 more
doaj   +1 more source

Long‐Term Efficacy of Immunotherapy in Autoimmune Autonomic Ganglionopathy—A 10‐Year Follow Up Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Autoimmune autonomic ganglionopathy (AAG) is a rare but potentially treatable cause of severe autonomic failure. Evidence guiding long‐term immunotherapy, treatment sequencing, and residual autonomic impairment is limited. We evaluated long‐term treatment response, residual autonomic dysfunction, and relapse patterns in patients with
Giacomo Chiaro, Shiwen Koay, Gordon T. Ingle, Patricia McNamara, Laura Watson, Fion Bremner, Valeria Iodice   +6 more
wiley   +1 more source

Social anxiety disorder [PDF]

The Lancet, 2008
Our understanding of social anxiety disorder (also known as social phobia) has moved from rudimentary awareness that it is not merely shyness to a much more sophisticated appreciation of its prevalence, its chronic and pernicious nature, and its neurobiological underpinnings.
Murray B, Stein, Dan J, Stein
openaire   +2 more sources

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon, Ka‐Ho Wong, Mirriam Mananah, Christopher D. Anderson, Ada Fenick, Amy Arnsten, Arman Fesharaki‐Zadeh, James C. McPartland, Mary L. Adams, Kevin N. Sheth   +9 more
wiley   +1 more source

Synergism between two BLA-to-BNST pathways for appropriate expression of anxiety-like behaviors in male mice

Nature Communications
Understanding how distinct functional circuits are coordinated to fine-tune mood and behavior is of fundamental importance. Here, we observe that within the dense projections from basolateral amygdala (BLA) to bed nucleus of stria terminalis (BNST ...
Ren-Wen Han, Zi-Yi Zhang, Chen Jiao, Ze-Yu Hu, Bing-Xing Pan   +4 more
doaj   +1 more source