Results 71 to 80 of about 2,401,638 (302)

Progressive Parkinsonism in PPP2R5D‐Related Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT PPP2R5D‐related neurodevelopmental disorder (Houge–Janssens syndrome type 1) is a rare autosomal dominant condition characterized by macrocephaly, intellectual disability, and epilepsy. Progressive parkinsonism is an emerging adult phenotype that neurologists should be aware of since timely genetic diagnosis opens the door to disease‐modifying
Katerina Bernardi, Enrique Gonzalez Saez‐Diez, Joshua Rong, Beril Ay, Shabbir Merchant, Kathryn Yang, Darius Ebrahimi‐Fakhari   +6 more
wiley   +1 more source

Changes in Immune‐Inflammation Status and Prognosis in Pregnancy‐Related Cerebral Venous Thrombosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Distinguishing pathological changes from physiological adaptations in pregnancy‐related cerebral venous thrombosis (CVT) is clinically challenging. This study aimed to characterize coagulation, immune‐inflammation, and dehydration status in these patients and assess their prognostic value.
Xiaoming Zhang, Zilin Xu, Ran Duan, Chunxiao Lu, Da Zhou, Chen Zhou, Ran Meng, Xunming Ji   +7 more
wiley   +1 more source

Predictors of long-term outcome of CBT for youth with anxiety disorders treated in community clinics

, 2018
Cognitive behavioral therapy (CBT) has proven long-term effects in youth with anxiety disorders. However, only a few studies have examined predictors of long-term outcomes of CBT treatment.
Gjestad, Rolf, Wergeland, Gro Janne H., Bjelland, Ingvar, Kodal, Arne, Haugland, Bente S. M., Öst, Lars-Göran,, Havik, Odd E., Heiervang, Einar R., Fjermestad, Krister W., Bjaastad, Jon F.   +9 more
core   +1 more source

Ventrolateral prefrontal cortex activation and attention bias in response to angry faces in adolescents with generalized anxiety disorder [PDF]

, 2006
OBJECTIVE: While adolescent anxiety disorders represent prevalent, debilitating conditions, few studies have explored their brain physiology. Using event-related functional magnetic resonance imaging (fMRI) and a behavioral measure of attention to angry ...
Erin Mcclure, Karin Mogg, Monique Ernst, Christopher S. Monk, Ernst, Monique, Monk, Christopher, Nelson, Eric E., Charney, Dennis S., Ellen Leibenluft, Bradley, Brendan P, Monk, Christopher S., James R, Dennis S. Charney, Chen, Gang, Chen, Geng, Gang Chen, Eric E. Nelson, Nelson, Eric E, Christopher Monk, McClure, Erin, Leibenluft, Ellen, Brendan P. Bradley, Erin B. Mcclure, Blair, James R., Pine, Daniel, Daniel Pine, Bradley, Brendan P., Blair, James R, Mogg, Karin, Pine, Daniel S, McClure, Erin B., McClure, Erin B, Pine, Daniel S., Charney, Dennis S   +33 more
core   +1 more source

A Novel KCNA1 Variant in a Patient With Tremor and Autism Spectrum Disorder Causes Mixed LOF/GOF Defects of Kv1.1 Channels

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Variants in KCNA1, encoding the Kv1.1 potassium channel, cause neurological disorders including episodic ataxia and developmental and epileptic encephalopathy. We identified a novel KCNA1 variant (A401T) in a 16‐year‐old patient with autism spectrum disorder, borderline intellectual disability, and tremor, without episodic ataxia or epilepsy ...
Juan Darío Ortigoza‐Escobar, Laura Marti‐Sánchez, Loreto Martorell, Giorgia Dinoi, Antonio Vittorio Buono, Annamaria De Luca, Antonella Liantonio, Paola Imbrici   +7 more
wiley   +1 more source

Explainable counterfactual reasoning in depression medication selection at multi-levels (personalized and population)

BMC Medical Informatics and Decision Making
Background This study investigates how variations in Major Depressive Disorder (MDD) symptoms (HAM-D) are associated in a predictive model with randomized clinical trial (RCT) arm assignment between SSRIs and SNRIs.
Xinyu Qin, Mark H. Chignell, Alexandria Greifenberger, Sachinthya Lokuge, Elssa Toumeh, Tia Sternat, Martin Katzman, Lu Wang   +7 more
doaj   +1 more source

Brief intermittent intense exercise as interoceptive exposure for panic disorder: a randomized controlled clinical trial

Frontiers in Psychiatry
BackgroundInteroceptive exposure (IE) to feared bodily sensations is a core component of cognitive–behavioral therapy for panic disorder (PD), but standard office-based IE can be perceived as aversive and tedious, potentially limiting engagement ...
Ricardo William Muotri, Alan Campos Luciano, Alia Garrudo Guirado, Francisco Lotufo Neto, Márcio Bernik   +4 more
doaj   +1 more source

Social anxiety disorder [PDF]

The Lancet, 2008
Our understanding of social anxiety disorder (also known as social phobia) has moved from rudimentary awareness that it is not merely shyness to a much more sophisticated appreciation of its prevalence, its chronic and pernicious nature, and its neurobiological underpinnings.
Murray B, Stein, Dan J, Stein
openaire   +2 more sources

Formal and Informal Social Care in People With Rheumatic and Musculoskeletal Diseases: A Cross‐Sectional Multicenter Survey

Arthritis Care &Research, EarlyView.
Objective Rheumatic and musculoskeletal diseases (RMDs) are leading causes of physical disability, necessitating support with activities of daily living. This study describes social care received by patients with RMDs in two disparate regions of England: Salford (urban) and Norfolk (rural).
Mehreen Somro, Karen Durrant, William G. Dixon, John McBeth, Alex MacGregor, Max Yates, Jenny H. Humphreys   +6 more
wiley   +1 more source

Exploration of NMDA and GABA receptor-mediated plasticity induced by 10-Hz repetitive transcranial magnetic stimulation

Translational Psychiatry
Although 10-Hz repetitive transcranial magnetic stimulation (rTMS) is an FDA-approved treatment for depression, we do not understand the mechanisms through which rTMS induces therapeutic change.
Jamie Kweon, Hakjoo Kim, Prem Ganesh, Megan M. Vigne, Andrew M. Fukuda, Boyu Ren, Linda L. Carpenter, Joshua C. Brown   +7 more
doaj   +1 more source