Results 111 to 120 of about 1,196,037 (307)
Advanced Materials, EarlyView.A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen +16 more
wiley +1 more source
Incidental threat during visuospatial working memory in adolescent anxiety: an emotional memory-guided saccade task [PDF]
, 2015 BackgroundPediatric anxiety disorders are among the most common psychiatric mental illnesses in children and adolescents, and are associated with abnormal cognitive control in emotional, particularly threat, contexts.
Ernst, M +5 more
core +1 more source
Current Psychiatry Reports, 2019 Anxiety disorders are among the most common mental disorders with a lifetime prevalence of over 20%. Clinically, anxiety is not thought of as a homogenous disorder, but is subclassified in generalized, panic, and phobic anxiety disorder. Anxiety disorders are moderately heritable.
Meier, Sandra M., Deckert, Jürgen
openaire +3 more sources
Enhancing Small Molecule Sensing With Aptameric Functionalized Nano Devices
Advanced Materials Technologies, EarlyView.Unveiling an ultra‐sensitive, non‐invasive neurotransmitter sensor. For the first time, a nanoscale sensor for detecting an important neurotransmitter was demonstrated using micro‐electromechanical systems (MEMS) technology. Our approach utilized field‐effect transistor (FET)‐based readout to enable pico‐molar detection of biomarkers in sweat.
Thi Thanh Ha Nguyen +11 more
wiley +1 more source
Journal of Affective Disorders ReportsBackground: Depression and anxiety are prevalent among persons living with multiple sclerosis (plwMS) and are linked to negative prognostic outcomes. Cognitive theories posit that personality and cognitive factors confer risk for depression and anxiety ...
Rebekah A. Davenport +5 more
doaj +1 more source
Face processing in adolescents with positive and negative threat bias [PDF]
, 2016 BackgroundIndividuals with anxiety disorders exhibit a ‘vigilance-avoidance’ pattern of attention to threatening stimuli when threatening and neutral stimuli are presented simultaneously, a phenomenon referred to as ‘threat bias’.
Barch, D.M. +3 more
core +2 more sources
Advanced Robotics Research, EarlyView.A soft robotic simulator is developed to replicate the digital removal of feces (DRF), a sensitive yet essential nursing procedure. Integrating soft actuators, sensors, and a realistic rectal model, the simulator balances functional fidelity with perceptual realism. Engineering evaluations and nurse feedback confirm its potential to enhance training in
Shoko Miyagawa +10 more
wiley +1 more source
A Central Somatic Transmission Mediates Proprioceptive Facilitation of Muscle Pain
Advanced Science, EarlyView.Zhang et al. uncover a novel central mechanism for persistent muscle pain, in which TRPA1 sensitization in MeV proprioceptive neurons enhances somatic secretion. This, in turn, disinhibits descending pain control from neighboring noradrenergic locus coeruleus neurons via local GABAergic circuits, thereby promoting inflammatory muscle pain.
Xiaoyu Zhang +15 more
wiley +1 more source
Frontiers in Psychiatry, 2018 Sufficient sleep plays an important role in neurocognitive function, yet, problematic sleep is ubiquitous in the general population. It is also frequently predictive of, and concurrent with, internalizing psychopathologies (IPs) such as anxiety and ...
Heide Klumpp +5 more
doaj +1 more source
A Behavioral Test of Contamination Fear in Excessive Health Anxiety [PDF]
, 2012 Hypochondriasis and health anxiety are characterized by preoccupation with the fear of currently having a serious physical illness. The Diagnostic and Statistical Manual of Mental Disorders conceptualization of hypochondriasis does not include ...
Brady, Robert Edwin
core +2 more sources