Results 141 to 150 of about 1,211,565 (358)

Validity and Reliability of the Turkish Version of Generalized Anxiety Disorder Scale-Revised [PDF]

, 2021
Anıl Gündüz, İbrahi̇m Gündoğmuş, Sencan Sertçelik, Betül Hacer Engin, Aysel İşler, Alişan Burak Yaşar, Hatice Gönül, Arif Çipil, Elvan Başak Usta Gündüz   +8 more
openalex   +1 more source

Taurocholic Acid Is Associated With Disturbed Functional Connectivity in the Hippocampus of Patients With Depression

Advanced Science, EarlyView.
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai, Taipeng Sun, Mengzhen Feng, Gang Chen, Junchi Zhou, Hong Zhuang, Dan Wang, Ying Chen, Zhen Cheng, Zhi Xu, Xiao Zheng, Xueli Zhang, Yonggui Yuan   +12 more
wiley   +1 more source

Effect of sleep quality on repetitive transcranial magnetic stimulation outcomes in depression

Frontiers in Psychiatry
IntroductionWhile repetitive transcranial magnetic stimulation (rTMS) is effective for 50-60% of those treatment-resistant depression, it is critical to identify predictors of response for optimal patient selection to improve therapy. Insomnia is a known
Jamie Kweon, Andrew M. Fukuda, Andrew M. Fukuda, Asi P. Gobin, Lamaan Haq, Linda L. Carpenter, Linda L. Carpenter, Joshua C. Brown, Joshua C. Brown   +8 more
doaj   +1 more source

Psychometric properties of the Generalised Anxiety Disorder Dimensional Scale in an Australian sample

, 2023
David G. Groves, Theodora Binasis, Bethany M. Wootton, Karen Moses   +3 more
openalex   +1 more source

Mitochondrial CISD1 Modulates Microglial Metabolic Reprogramming to Drive Stress Susceptibility in Mice

Advanced Science, EarlyView.
CDGSH iron sulfur domain 1 (CISD1) mitigates oxidative stress by promoting NADH oxidation and Coenzyme Q (CoQ) reduction. Under chronic stress, elevated CISD1 expression in microglia enhances NAD⁺ production, thereby increasing GAPDH activity and glycolytic flux, while reducing ATP synthesis by inhibiting proton transfer from mitochondrial complexes I ...
Wanting Dong, Duo Liu, Songsen Fu, Jiaming Zhang, Xi Chen, Songqiang Huang   +5 more
wiley   +1 more source

Predicting Tending to Callous-Unemotional Traits Based on Empathy, Social Anxiety Disorder and Bullying in Students

, 2020
Arezoo Paliziyan, Arezoo Javadi Koma, Mehrnaz Mehrabizade Honarmand   +2 more
openalex   +2 more sources

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Inflammatory markers changes following acceptance-based behavioral psychotherapy in generalized anxiety disorder patients: Evidence from a randomized controlled trial

Brain, Behavior, & Immunity - Health
Introduction: Generalized anxiety disorder (GAD) has been associated with elevated levels of C-reactive protein (CRP) and proinflammatory cytokines.
Lucas Gandarela, Thiago P. de A. Sampaio, Lia Marçal, Emmanuel A. Burdmann, Francisco Lotufo Neto, Marcio A. Bernik   +5 more
doaj   +1 more source

Generalized anxiety disorder, depressive symptoms and sleep quality during COVID-19 epidemic in China: a web-based cross-sectional survey [PDF]

, 2020
Yeen Huang, Ning Zhao
openalex   +1 more source

Anxiety, Anxiety Disorders, Religion and Spirituality

Southern Medical Journal, 2007
The article provides a brief overview of the literature on religion and anxiety. Then, in a discussion of two case vignettes, an impression is given of how religious and spiritual issues interact with anxiety in the clinical (psychiatric) situation. In the final part it is indicated how these religious and spiritual issues may be addressed.
openaire   +3 more sources