Results 11 to 20 of about 537,076 (316)

Mediating the relationship between neuroticism and depressive, anxiety and eating disorder symptoms: The role of intolerance of uncertainty and cognitive flexibility

Journal of Affective Disorders Reports, 2021
Background: Research has found that IU (Intolerance of Uncertainty) and CF (Cognitive Flexibility) have separately been associated with depression, anxiety and eating disorders as a transdiagnostic vulnerability.
Erica Clarke, Litza A Kiropoulos
doaj   +1 more source

Meta-analysis of the variability in the individual response to pharmacological treatments for mania in bipolar disorder

European Psychiatry, 2023
Introduction Many studies have investigated whether there exist predictors of good response to antimanic drugs in bipolar disorder (BD). However, these factors predict response or only indicate benign illness course. Objectives To shed some light on the
G. Anmella, M. De Prisco, V. Oliva, M. Sanabra, L. Fortea, M. Ortuño, G. Fico, A. Murru, E. Vieta, D. Hidalgo-Mazzei, A. Solanes, J. Radua   +11 more
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A resource of induced pluripotent stem cell (iPSC) lines including clinical, genomic, and cellular data from genetically isolated families with mood and psychotic disorders

Translational Psychiatry, 2023
Genome-wide (GWAS) and copy number variant (CNV) association studies have reproducibly identified numerous risk alleles associated with bipolar disorder (BD), major depressive disorder (MDD), and schizophrenia (SCZ), but biological characterization of ...
Sevilla D. Detera-Wadleigh, Layla Kassem, Emily Besancon, Fabiana Lopes, Nirmala Akula, Heejong Sung, Meghan Blattner, Laura Sheridan, Ley Nadine Lacbawan, Joshua Garcia, Francis Gordovez, Katherine Hosey, Cassandra Donner, Claudio Salvini, Thomas Schulze, David T. W. Chen, Bryce England, Joanna Cross, Xueying Jiang, Winston Corona, Jill Russ, Barbara Mallon, Amalia Dutra, Evgenia Pak, Joe Steiner, Nasir Malik, Theresa de Guzman, Natia Horato, Mariana B. Mallmann, Victoria Mendes, Amanda L. Dűck, Antonio E. Nardi, Francis J. McMahon   +32 more
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The Yale-Brown Obsessive-Compulsive scale: factor structure of a large sample

Frontiers in Psychiatry, 2010
The Yale Brown Obsessive-Compulsive scale (Y-BOCS) is a semi-structured interview considered to be the gold standard in the measurement of obsessive-compulsive disorder (OCD) severity, yet findings about its factorial structure are conflicting.
Gideon Anholt, Patricia v Oppen, Danielle Cath, Danielle Cath, Jan Smit, Johan A Den Boer, Marc J P Verbraak, Marc J P Verbraak, Marc J P Verbraak, Anton J L Van Balkom   +9 more
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The enhancing effects of testosterone in exposure treatment for social anxiety disorder: a randomized proof-of-concept trial

Translational Psychiatry, 2021
Individuals with a social anxiety disorder (SAD) show hypofunctioning of the hypothalamus–pituitary-gonadal (HPG) axis, which is linked to social fear and avoidance behavior.
Moniek H. M. Hutschemaekers, Rianne A. de Kleine, Gert-Jan Hendriks, Mirjam Kampman, Karin Roelofs   +4 more
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Genetics of Anxiety Disorders

Current Psychiatry Reports, 2019
Anxiety disorders are among the most common mental disorders with a lifetime prevalence of over 20%. Clinically, anxiety is not thought of as a homogenous disorder, but is subclassified in generalized, panic, and phobic anxiety disorder. Anxiety disorders are moderately heritable.
Meier, Sandra M., Deckert, Jürgen
openaire   +3 more sources

A pilot exploration of ADHD symptoms in hoarding disorder: Co-occurring disorders or part of the hoarding syndrome?

Journal of Affective Disorders Reports, 2023
Background: Symptoms of ADHD are common in individuals with hoarding disorder (HD). It remains unclear whether these attentional symptoms reflect high co-occurrence rates of ADHD and HD, or whether inattentive symptoms can be conceptualized as intrinsic ...
Blaise L. Worden, David F. Tolin
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New Therapeutic Targets for Mood Disorders

The Scientific World Journal, 2010
Existing pharmacological treatments for bipolar disorder (BPD) and major depressive disorder (MDD) are often insufficient for many patients. Here we describe a number of targets/compounds that clinical and preclinical studies suggest could result in ...
Rodrigo Machado-Vieira, Giacomo Salvadore, Nancy DiazGranados, Lobna Ibrahim, David Latov, Cristina Wheeler-Castillo, Jacqueline Baumann, Ioline D. Henter, Carlos A. Zarate   +8 more
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Emergency care provision for, and psychological distress in, survivors of domestic violence

South African Family Practice, 2007
Background: This study aimed (i) to ascertain the number of treatment referrals and information about protection orders given to survivors of domestic violence presenting for emergency trauma care, as reported at the one-month visit, (ii) to obtain a ...
Kate Joyner, Lennette Theunissen, Liezel de Villiers, Sharain Suliman, Timothy Hardcastle, Soraya Seedat   +5 more
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Chronic Stress Oppositely Regulates Tonic Inhibition in Thy1-Expressing and Non-expressing Neurons in Amygdala

Frontiers in Neuroscience, 2020
Chronic or prolonged exposure to stress ranks among the most important socioenvironmental factors contributing to the development of neuropsychiatric diseases, a process generally associated with loss of inhibitory tone in amygdala.
Han-Qing Pan, Han-Qing Pan, Wen-Hua Zhang, Wen-Hua Zhang, Cai-Zhi Liao, Cai-Zhi Liao, Ye He, Zhi-Ming Xiao, Xia Qin, Xia Qin, Wei-Zhu Liu, Wei-Zhu Liu, Na Wang, Jia-Xin Zou, Jia-Xin Zou, Xiao-Xuan Liu, Xiao-Xuan Liu, Bing-Xing Pan, Bing-Xing Pan   +18 more
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