Results 21 to 30 of about 537,076 (316)

Circulating PACAP levels are associated with altered imaging measures of entorhinal cortex neurite density in posttraumatic stress disorder

European Journal of Psychotraumatology
Introduction: Pituitary adenylate cyclase-activating polypeptide (PACAP) regulates plasticity in brain systems underlying arousal and memory and is associated with posttraumatic stress disorder (PTSD).
Steven J. Granger, Victor May, Sayamwong E. Hammack, Eylül Akman, Sydney A. Jobson, Elizabeth A. Olson, Cameron D. Pernia, Nikos P. Daskalakis, Caitlin Ravichandran, William A. Carlezon, Kerry J. Ressler, Scott L. Rauch, Isabelle M. Rosso   +12 more
doaj   +1 more source

Relation of Adverse Childhood Experiences to Clinical and Patient‐Reported Outcomes for Adults With Sickle Cell Disease: A Registry Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adverse childhood experiences (ACEs) are stressful or traumatic events prior to age 18 that are known to have a lasting impact on individuals’ health and well‐being. There is a gap in understanding the relationship between ACEs and Other Life Stressors and health status for adults with sickle cell disease (SCD).
Marsha Treadwell, Jessica Liang, Liliana Preiss, Angela Rivers, Jane S. Hankins, Allison King, Justin Williams, Michael B. Potter, Danielle Hessler   +8 more
wiley   +1 more source

Trauma-related intrusive memories and anterior hippocampus structural covariance: an ecological momentary assessment study in posttraumatic stress disorder

Translational Psychiatry
Trauma-related intrusive memories (TR-IMs) are hallmark symptoms of posttraumatic stress disorder (PTSD), but their neural correlates remain partly unknown.
Quentin Devignes, Boyu Ren, Kevin J. Clancy, Kristin Howell, Yara Pollmann, Lucia Martinez-Sanchez, Courtney Beard, Poornima Kumar, Isabelle M. Rosso   +8 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Specific symptom change associated with ecological momentary assessments of intrusive trauma memories

NPP-Digital Psychiatry and Neuroscience
As the global prevalence of exposure to traumatic events rises, there is a growing need for accessible and scalable treatments for trauma-related disorders like posttraumatic stress disorder (PTSD).
Yara Pollmann, Kevin J. Clancy, Quentin Devignes, Boyu Ren, Milissa L. Kaufman, Isabelle M. Rosso   +5 more
doaj   +1 more source

Social anxiety disorder [PDF]

The Lancet, 2008
Our understanding of social anxiety disorder (also known as social phobia) has moved from rudimentary awareness that it is not merely shyness to a much more sophisticated appreciation of its prevalence, its chronic and pernicious nature, and its neurobiological underpinnings.
Murray B, Stein, Dan J, Stein
openaire   +2 more sources

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Characteristics and outcomes of individuals screening positive for borderline personality disorder on an adult inpatient psychiatry unit: a cross-sectional study

BMC Psychiatry
Background Outpatient psychotherapies are gold standard interventions for borderline personality disorder (BPD); however, in clinical reality, higher rates of psychiatric hospitalization and more severe symptoms, including suicidality and self-harm ...
Joann J. Chen, Sam A. Mermin, Lucie A. Duffy, Samantha A. Wong, Savannah D. Layfield, Fernando Rodriguez-Villa, Steven E. Gelda, Eliot M. Gelwan, Jane Eisen, Kerry J. Ressler, Lois W. Choi-Kain, Agustin G. Yip   +11 more
doaj   +1 more source

Psychopathology and coping in recently diagnosed HIV/AIDS patients - the role of gender

South African Journal of Psychiatry, 2004
Background. Although there is growing literature on the psy- chological responses to and the psychopathology associated with HIV/AIDS, few investigations have focused on the role of gender. This study compared psychiatric morbidity, coping responses, and
Benjamin O Olley, Faniswa Gxamza, Soraya Seedat, Hugo Theron, Dan J Stein, Jantjie Taljaard, Emile Reid, Helmuth Reuter   +7 more
doaj   +1 more source

Impact of Hoarding and Obsessive–Compulsive Disorder Symptomatology on Quality of Life and Their Interaction With Depression Symptomatology

Frontiers in Psychology, 2022
Hoarding disorder (HD) is a psychiatric condition characterized by difficulty discarding items and accumulation of clutter. Although studies have established the negative impact of HD and compulsive hoarding behavior, fewer have examined the impact on ...
Binh K. Nguyen, Binh K. Nguyen, Jessica J. Zakrzewski, Jessica J. Zakrzewski, Luis Sordo Vieira, Luis Sordo Vieira, Luis Sordo Vieira, Carol A. Mathews, Carol A. Mathews   +8 more
doaj   +1 more source