Results 81 to 90 of about 537,076 (316)

Lithium‐Charged Gold Nanoparticles: A New Powerful Tool for Lithium Delivery and Modulation of Glycogen Synthase Kinase 3 Activity

open access: yesAdvanced Materials, EarlyView.
This study introduces glutathione‐stabilized gold nanoparticles for targeted lithium delivery (LiG‐AuNPs), enabling the controlled modulation of Glycogen Synthase Kinase‐3 (GSK‐3β). These non‐toxic, 2‐nm particles release lithium intracellularly, effectively inhibiting GSK‐3β in the brain without significant plasma lithium alterations.
Antonio Buonerba   +20 more
wiley   +1 more source

Self-poisoning suicide deaths in people with bipolar disorder: characterizing a subgroup and identifying treatment patterns

open access: yesInternational Journal of Bipolar Disorders, 2017
Objective To characterize self-poisoning suicide deaths in BD compared to other suicide decedents. Methods Extracted coroner data from all suicide deaths (n = 3319) in Toronto, Canada from 1998 to 2012.
Ayal Schaffer   +6 more
doaj   +1 more source

E‐Textiles in Biomedicine: Real Time Sensing, Energy Storage, and Therapeutic Applications

open access: yesAdvanced Materials Interfaces, EarlyView.
E‐textiles merge electronics with fabrics to create intelligent, wearable systems for health, sports, and fashion. By embedding sensors, actuators, and conductive components, these textiles provide real‐time physiological monitoring. Complemented by flexible power sources including embedded batteries and energy‐harvesting technologies, e‐textiles ...
Shiva Sharma   +4 more
wiley   +1 more source

Measuring Anxiety Symptoms – Psychometric Properties of the Dutch Version of the Lehrer–Woolfolk Anxiety Scale Questionnaire

open access: yesPsychological Test Adaptation and Development
: Introduction: The Lehrer–Woolfolk Anxiety Symptom Questionnaire (LWASQ) is a self-report questionnaire based on the tripartite model of Lang (1971) for measuring treatment progress. However, so far little is known about its psychometric qualities.
Vivian Peerbooms   +4 more
doaj   +1 more source

Soft Robotic Excretory Care Simulator for Nursing Education: Functional and Perceptual Biomimetics Approach

open access: yesAdvanced Robotics Research, EarlyView.
A soft robotic simulator is developed to replicate the digital removal of feces (DRF), a sensitive yet essential nursing procedure. Integrating soft actuators, sensors, and a realistic rectal model, the simulator balances functional fidelity with perceptual realism. Engineering evaluations and nurse feedback confirm its potential to enhance training in
Shoko Miyagawa   +10 more
wiley   +1 more source

Associations between PACAP levels and psychophysiological indicators of fear and arousal in adults with posttraumatic stress symptoms

open access: yesJournal of Mood and Anxiety Disorders
Posttraumatic stress disorder (PTSD) is associated with heightened fear responding and decreased fear regulation, as demonstrated with psychophysiological measures (e.g., autonomic function) and circulating biomarkers of stress, such as pituitary ...
Antonia V. Seligowski   +12 more
doaj   +1 more source

Multitasking Smart Intestinal Capsule Robot: A Cutting‐Edge Platform for Sampling, Diagnosis, and Therapy

open access: yesAdvanced Robotics Research, EarlyView.
Gut microbiota and biomarkers are linked to diseases like neurological disorders and metabolic syndromes. Ingestible capsule robots enable minimally invasive gut health assessment. This article proposes a promising direction for the advancement of capsule robots, integrating in situ sampling, real‐time diagnostics, and personalized therapy.
Xizong Chen   +3 more
wiley   +1 more source

Exploring individual differences in fear extinction in male and female mice: insights from HPA axis, microbiota, and transcriptomics

open access: yesTranslational Psychiatry
Exposure to traumatic life events may compromise physical and mental health of specific subjects. While some individuals extinguish fear appropriately, others exhibit an inefficient and persistent fear response, with remarkable differences between sexes.
Marc Ten-Blanco   +7 more
doaj   +1 more source

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