Results 221 to 230 of about 45,720 (293)

Memory-Enhancing and Anxiolytic Effects of the Rose of Jericho on Sleep Deprivation-Related Cognitive and Behavioral Changes. [PDF]

Cureus
Mustafa SA, Alsaeed J, Alyaseen EM, Alhazmi RA, Alhazmi RA, Alzahrani MS, Almehmadi NM, Al Ali FA, Salman SS, Marwani AM, Husni M, Naguib YM.   +11 more
europepmc   +1 more source

Effects of Oral Macrocyclic Lactone Heartworm Preventatives on Retinal Function and Chromatic Pupillary Light Reflex in Healthy Companion Dogs

Veterinary Ophthalmology, EarlyView.
ABSTRACT Objective Determine the effect of oral macrocyclic lactone heartworm‐preventative medications on retinal function and chromatic pupillary light reflex (cPLR) in healthy dogs. Animals Studied Cross‐sectional retrospective: 60 dogs (n = 33 females) with heartworm medication administration status and electroretinogram (ERG) data available ...
Ryan G. Hopper, Allison L. Ludwig, Michele M. Salzman, Ethan Elazegui, Callie M. Rogers, Ellison Bentley, Freya M. Mowat   +6 more
wiley   +1 more source

Distinguishing classes of neuroactive drugs based on computational physicochemical properties and experimental phenotypic profiling in planarians. [PDF]

PLoS One
Ireland D, Rabeler C, Rao S, Richardson RJ, Collins ES.   +4 more
europepmc   +1 more source

The mood stabilizers lithium and valproate disrupt hepatic and intestinal farnesoid X receptor signalling and increase bile synthesis in the rat

Experimental Physiology, EarlyView.
Abstract The mood stabilizers lithium and valproate are psychotropic medications widely used in clinical practice. Despite their proven benefits, many individuals stop their treatment due to the adverse effects. Chronic diarrhoea is a common reason for discontinuation of these drugs; however, the underlying mechanisms are unknown.
Sofia Cussotto, Anna V. Golubeva, Alvaro Lopez Gallardo, Thomaz F. S. Bastiaanssen, Alexander V. Zhdanov, Gerard M. Moloney, Caitriona Scaife, Jane A. English, Susan A. Joyce, Timothy G. Dinan, John F. Cryan   +10 more
wiley   +1 more source

Aromatherapy and Essential Oils: Holistic Strategies in Complementary and Alternative Medicine for Integral Wellbeing. [PDF]

Plants (Basel)
Caballero-Gallardo K, Quintero-Rincón P, Olivero-Verbel J.   +2 more
europepmc   +1 more source

GABAB Receptor: Structure, Biological Functions, and Therapy for Diseases

MedComm, Volume 6, Issue 5, May 2025.
Within the GABAergic system, GABABRs are potential therapeutic targets for dealing multiple metabolic and binge eating disorders and food addiction. Allosteric modulators and small peptides targeting GABABR signaling pathways may be developed as attractive drug candidates that avoid the side effects of agents that directly bind these receptors ...
Weijie Xie, Yuan Li, Xinyue Wang, Elena Blokhina, Evgeny Krupitsky, Marina Vetrova, Ji Hu, Ti‐Fei Yuan, Jue Chen, Hua Wang, Xiangfang Chen   +10 more
wiley   +1 more source

Antidepressive and anxiolytic effects of a combination of Saffron and Chamomile in rats and their relationship with serotonin using methods. [PDF]

J Tradit Chin Med
Amin F, Ahmad S, Wasim M, Khan A, Manzoor Arain F, Batool Z, Tabassum S, Khaliq S, Samad N, Haider S.   +9 more
europepmc   +1 more source

Dysregulation of Astrocytic ATP/Adenosine Release in the Hippocampus Cause Cognitive and Affective Disorders: Molecular Mechanisms, Diagnosis, and Therapy

MedComm, Volume 6, Issue 5, May 2025.
Reactive astrocytes release various molecules, which play a role in maintaining central nervous system (CNS) homeostasis. (1) Gliotransmitters, such as glutamate, γ‐aminobutyric acid (GABA), ATP, and D‐serine, are secreted by vesicular exocytosis. In addition, astrocytes can also release ATP and glutamate through (2) P2X7Rs, (3) connexin‐43 (Cx43 ...
Peter Illes, Patrizia Rubini, Henning Ulrich, Hai‐Yan Yin, Yong Tang   +4 more
wiley   +1 more source

The Influence of the Estrous Cycle on Neuropeptide S Receptor-Mediated Behaviors. [PDF]

J Pharmacol Exp Ther
Costa PC, Salinas B, Wojciechowski A, Wood SK, Runyon S, Clark SD.   +5 more
europepmc   +1 more source