Alcohol‐Induced Disinhibition of Facial Responses to Pain
European Journal of Pain, Volume 29, Issue 8, September 2025.ABSTRACT Background Alcohol in sub‐toxic dosages has appeared to slightly reduce experimental pain in psychophysical paradigms. However, this effect may also reflect impaired scaling performance in subjective ratings. To address this, we additionally assessed facial responses as a more direct and cognitively unbiased pain measure, while acknowledging ...
Stefan Lautenbacher +4 more
wiley +1 more source
Ethnopharmacological Profile, Phytochemistry and Therapeutic Potential of <i>Aegle marmelos</i> L. for the Treatment of Neurological Disorders. [PDF]
J Nutr MetabSharma A +10 more
europepmc +1 more source
It Is Time to Feel Better: How Temporal Information of Placebo Analgesia Affects Our Brain
European Journal of Pain, Volume 29, Issue 8, September 2025.ABSTRACT Background Placebo and nocebo effects have been thoroughly studied during the last decades using pain models. Two characteristics have been investigated, namely the direction of the effects (i.e., placebo, amelioration of symptoms/nocebo, worsening of symptoms) and their magnitude (i.e., the robustness of the effects).
Volpino Valeria +5 more
wiley +1 more source
Involvement of the GABAergic and the serotonergic systems in the anxiolytic effects expressed by the nitric oxide (NO) donor sodium nitroprusside (SNP) in the male rat. [PDF]
Psychopharmacology (Berl)Parlantza MA, Pitsikas N.
europepmc +1 more source
Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 344, Issue 6, Page 352-362, September 2025.Automated pose tracking and behavioral classification reveal distinct stress‐like responses in surface and cave morphs of Astyanax mexicanus. Surface fish exhibit freezing and bottom‐dwelling, while cavefish show reduced stress behaviors. Ethogram analyses highlight trait clustering, offering new insights into the evolution and genetic basis of stress ...
Naresh Padmanaban +7 more
wiley +1 more source
Astrocytes in Rodent Anxiety-Related Behavior: Role of Calcium and Beyond. [PDF]
Int J Mol SciGómez-Gonzalo M.
europepmc +1 more source
Zebrafish as a Versatile Model Organism: From Tanks to Treatment
MedComm – Future Medicine, Volume 4, Issue 3, September 2025.The zebrafish, with its optical transparency and genetic tractability, serves as a versatile in vivo platform for biomedical research. This review underscores its significance in modeling a wide spectrum of human diseases—from cancer to metabolic disorders—and in leveraging cutting‐edge technologies like CRISPR and TALENs.
Rupali Srivastava +9 more
wiley +1 more source
The Effects of Indirect and Direct Modulation of Endocannabinoid System Function on Anxiety-Related Behavior in Mice Assessed in the Elevated Plus Maze Test. [PDF]
MoleculesKruk-Slomka M, Dzik A, Biala G.
europepmc +1 more source
Pediatric Blood &Cancer, Volume 72, Issue 9, September 2025.ABSTRACT Purpose Curative therapy for most children with leukemia and lymphoma includes multiple lumbar punctures (LPs) for the administration of intrathecal chemotherapy, commonly facilitated with deep sedation or general anesthesia (GA). There is ongoing concern about the potential for neurocognitive deficits induced by GA in the developing brain ...
Karen Arane +7 more
wiley +1 more source