Glioblastoma mortality is driven by cell invasion and therapeutic resistance. We report a cancer engineering approach to evaluate the behavior of heterogeneous cohorts of temozolomide resistant and responsive GBM cells. We show the effect of physiologically‐relevant metronomic dosing on ensemble drug response and invasion.
Victoria A. Kriuchkovskaia +5 more
wiley +1 more source
amoA Gene Abundances and Nitrification Potential Rates Suggest that Benthic Ammonia-Oxidizing Bacteria and Not Archaea Dominate N Cycling in the Colne Estuary, United Kingdom [PDF]
Nitrification, mediated by ammonia-oxidizing bacteria (AOB) and ammonia-oxidizing archaea (AOA), is important in global nitrogen cycling. In estuaries where gradients of salinity and ammonia concentrations occur, there may be differential selections for ...
Alex J. Dumbrell +8 more
core +1 more source
Leader Succession and Strategic Change: The Role of Leader's Subgroups Size
ABSTRACT Research suggests that new CEO successors drive strategic change through the subgroup of their immediate collaborators. However, it remains unclear how this subgroup is configured. In this research, we address this limitation by introducing a new concept of “CEO's subgroup size” (the number of TMT members in the CEO's subgroup).
Yue Zhang, Oluremi B. Ayoko
wiley +1 more source
Extractable nitrogen and microbial community structure respond to grassland restoration regardless of historical context and soil composition. [PDF]
Grasslands have a long history of invasion by exotic annuals, which may alter microbial communities and nutrient cycling through changes in litter quality and biomass turnover rates.
Allen, Edith B +3 more
core +1 more source
Tree planting, natural colonisation, hybrid approaches: Land manager decisions explored
Abstract There is a global drive to protect biodiversity and help combat climate change. In the UK, this is expressed in a number of policy initiatives and tools that include increasing tree cover as an important nature‐based solution to achieving national policy targets.
Bianca Ambrose‐Oji +5 more
wiley +1 more source
Ammonia transformation by potential consortium in the aquatic system
In the present research, the removal of high concentration of ammonia, nitrite and nitrate was determined by using the efficient ammonia-oxidizing bacterial isolates (AOB AMS 1, AOB AMS 2, AOB AMS 5 and AOB AMSS 1) along with the consortium of all four ...
Anne Bhambri +2 more
doaj +1 more source
Ammonia-oxidizing archaea (AOA) and bacteria (AOB) are a diverse and functionally important group in the nitrogen cycle. Nevertheless, AOA and AOB communities driving this process remain uncharacterized in tropical freshwater sediment.
Mariana De Paula Reis +6 more
doaj +1 more source
Inherent variation of functional traits in winter and summer leaves of Mediterranean seasonal dimorphic species. Evidence of a 'within leaf cohort' spectrum [PDF]
The covariation pattern among leaf functional traits involved in resource acquisition has been successfully provided by the leaf economic spectrum (LES).
Puglielli, Giacomo, Varone, Laura
core +1 more source
Growing trees on farms: Navigating the goals and values of farmers
Abstract Agricultural landscapes represent critical contexts for advancing policy objectives related to tree cover expansion. This paper explores how farmers' values influence their willingness or ability to grow trees on farms. Research is based on 49 interviews and two focus groups with farmers in England and draws on two social science research ...
Stephen McConnachie +7 more
wiley +1 more source
Brain Cortex Activity in Children With Anterior Open Bite: A Pilot Study
Anterior open bite (AOB) is related to functional alterations of the stomatognathic system. There are no studies concerning brain activation of the cortex comparing children with and without AOB during rest and activities such as deglutition and ...
Claudia Restrepo +4 more
doaj +1 more source

