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Linking TLR-7 Signaling to Downregulation of Placental P-Glycoprotein: Implications for Fetal Drug Exposure. [PDF]
PharmaceuticsRiera-Romo M +2 more
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Amine Oxidase Copper-containing 1 (AOC1) Is a Downstream Target Gene of the Wilms Tumor Protein, WT1, during Kidney Development [PDF]
Journal of Biological Chemistry, 2014 Amine oxidase copper-containing 1 (AOC1; formerly known as amiloride-binding protein 1) is a secreted glycoprotein that catalyzes the degradation of putrescine and histamine. Polyamines and their diamine precursor putrescine are ubiquitous to all organisms and fulfill pivotal functions in cell growth and proliferation. Despite the importance of AOC1 in
Karin Kirschner, Holger Scholz
exaly +3 more sources
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Association of Serum Copper Levels and Amine Oxidase Copper Gene 1 (AOC1) with Migraineurs
Applied Science and Engineering Progress, 2021Migraine is a common neurovascular multifactorial disease with biochemical abnormalities in the central nervous system (CNS). It is characterized by episodes of frequent headaches, affecting about 14% of the world's population. Trace elements are essential to play an important role in neurotransmission and causing oxidative stress in patients with ...
Anne Sahithi Somavarapu Thomas +3 more
openaire +1 more source
Homopathic Links, 2020
AbstractThe new pandemic disease COVID-19 has wreaked havoc worldwide. Its infectious agent, SARS-CoV-2, uses two key human enzymes called angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) to invade body cells. The first one is encoded by the ACE2 gene and the second by the TMPRSS2 gene.
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AbstractThe new pandemic disease COVID-19 has wreaked havoc worldwide. Its infectious agent, SARS-CoV-2, uses two key human enzymes called angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) to invade body cells. The first one is encoded by the ACE2 gene and the second by the TMPRSS2 gene.
exaly +2 more sources
2023
The research project will provide new insights into pathomechanisms and repair processes in renal injury. In particular, the question will be answered whether the polyamine-degrading enzyme AOC1 is suitable as a target molecule for the treatment of renal injury.
openaire +1 more source
The research project will provide new insights into pathomechanisms and repair processes in renal injury. In particular, the question will be answered whether the polyamine-degrading enzyme AOC1 is suitable as a target molecule for the treatment of renal injury.
openaire +1 more source