Results 141 to 150 of about 2,570 (163)

Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model. [PDF]

Front Pharmacol
Horváth ÁI, Bölcskei K, Szentes N, Borbély É, Tékus V, Botz B, Rusznák K, Futácsi A, Czéh B, Mátyus P, Helyes Z.   +10 more
europepmc   +1 more source

Alternaria TeA toxin activates a chloroplast retrograde signaling pathway to facilitate JA-dependent pathogenicity. [PDF]

Plant Commun
Shi J, Wang H, Li M, Mi L, Gao Y, Qiang S, Zhang Y, Chen D, Dai X, Ma H, Lu H, Kim C, Chen S.   +12 more
europepmc   +1 more source

Transcriptomic profiling to investigate the therapeutic potential and medicinal properties of Momordica cymbalaria. [PDF]

Sci Rep
Krishnakumar H, Nallusamy S, Rajmichael R, Mathimaran A, Pandian CJ, Subramanian G, Jeyaraman J.   +6 more
europepmc   +1 more source

Myofibroblasts are distinguished from activated skin fibroblasts by the expression of AOC3 and other associated markers [PDF]

Proceedings of the National Academy of Sciences of the United States of America, 2016
SignificanceMyofibroblasts surround the epithelial cells of the crypts that form the surface of the gut. They play an important role in controlling the normal epithelium and influence the development of colorectal and other epithelial cancers. The definition of myofibroblasts previously depended almost entirely on the expression of smooth muscle actin.
Neil Ashley, Walter Bodmer
exaly   +4 more sources

Absence of the Endothelial Oxidase AOC3 Leads to Abnormal Leukocyte Traffic In Vivo [PDF]

Immunity, 2005
Leukocyte migration from the blood to tissues is a prerequisite for normal immune responses. We produced mice deficient in an endothelial cell-surface oxidase (amine oxidase, copper containing-3 [AOC3], also known as vascular adhesion protein-1 [VAP-1]) and found that this enzyme is needed for leukocyte extravasation in vivo.
Gennady G Yegutkin, Mikael Skurnik, Arno Hänninen   +2 more
exaly   +3 more sources

Endothelial amine oxidase AOC3 transiently contributes to adaptive immune responses in the airways [PDF]

European Journal of Immunology, 2014
Amine oxidase, copper containing 3 (AOC3, also known as vascular adhesion protein‐1 (VAP‐1)) is an endothelial adhesion molecule that contributes to the extravasation of neutrophils, macrophages, and lymphocytes to sites of inflammation. However, the role of AOC3/VAP‐1 in allergic responses remains unknown.
Johannes Dunkel, Juan Antonio Aguilar-Pimentel, Markus W Ollert   +2 more
exaly   +4 more sources

AOC3 opens doors for leukocytes [PDF]

Nature Reviews Immunology, 2005
exaly   +2 more sources

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Obesity of mice lacking VAP-1/SSAO by Aoc3 gene deletion is reproduced in mice expressing a mutated vascular adhesion protein-1 (VAP-1) devoid of amine oxidase activity

Journal of Physiology and Biochemistry, 2020
The product of Aoc3 gene is known as vascular adhesion protein-1 (VAP-1), a glycoprotein contributing to leukocyte extravasation and exhibiting semicarbazide-sensitive amine oxidase activity (SSAO). Regarding the immune functions of VAP-1/SSAO, it is known that mice bearing Aoc3 gene knock-out (AOC3KO) exhibit defects in leukocyte migration similar to ...
Philippe Valet, Anne Bouloumié, Pascale Mauriège   +2 more
exaly   +4 more sources

Tight regulation of allene oxide synthase (AOS) and allene oxide cyclase-3 (AOC3) promote Arabidopsis susceptibility to the root-knot nematode Meloidogyne javanica

European Journal of Plant Pathology, 2017
Biosynthesis of the oxylipin jasmonic acid (JA) in Arabidopsis thaliana is catalyzed by a single allene oxide synthase (AOS)-encoding gene and four genes encoding four functional allene oxide cyclase (AOC) polypeptides (AOC1, AOC2, AOC3, and AOC4). To elucidate the biological activities of the JA pathway in regulating the plant defense response to ...
Fatta B Gurung, Patricia Bucki, Payal Sanadhya   +2 more
exaly   +2 more sources