Results 51 to 60 of about 74,959 (254)

Frequency comb based four-wave-mixing spectroscopy [PDF]

, 2017
We experimentally demonstrate four-wave-mixing spectroscopy using frequency combs. The experiment uses a geometry where excitation pulses and four-wave-mixing signals generated by a sample co-propagate.
Cundiff, Steven T., Lomsadze, Bachana
core   +1 more source

Gemella morbillorum Promotes Colorectal Carcinogenesis: LPBDCP‐Mediated Invasion Activates Ras Signaling and Destabilizes p53

Advanced Science, EarlyView.
ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang, Jia Zhang, Haojie Lu, Jingjing Ni, Shuaishuai Yang, Yuting Shi, Shuo Zhang, Pei Zhang, Li Liu   +8 more
wiley   +1 more source

Parent-reported symptoms of acute otitis media during the first year of life: what is beneath the surface?

PLoS ONE, 2015
BackgroundMost estimates of the incidence of acute otitis media (AOM) are based on general practitioner (GP) or pediatrician diagnoses. It is likely that these figures underestimate the community incidence of AOM since parents do not visit their doctor ...
Alexandre C Fortanier, Roderick P Venekamp, Marieke L A de Hoog, Cuno S P M Uiterwaal, Anne C van der Gugten, Cornelis K van der Ent, Arno W Hoes, Anne G M Schilder   +7 more
doaj   +1 more source

COVID-19 and Acute Otitis Media in Children: A Case Series

Journal of Primary Care & Community Health, 2022
Background: The association of SARS-CoV-2 with acute otitis media (AOM) in children is poorly understood. Methods: Cases were identified as a subpopulation within the NO TEARS prospective AOM study in Denver, CO from March to December 2020.
Holly M. Frost, Thresia Sebastian, Amy Keith, Melanie Kurtz, Samuel R. Dominguez, Sarah K. Parker, Timothy C. Jenkins   +6 more
doaj   +1 more source

Chemotrophic Microbial Mats and Their Potential for Preservation in the Rock Record [PDF]

, 2009
Putative microbialites are commonly regarded to have formed in association with photosynthetic microorganisms, such as cyanobacteria. However, many modern microbial mat ecosystems are dominated by chemotrophic bacteria and archaea.
Bailey, Jake V., Corsetti, Frank A., Joye, Samantha B., Orphan, Victoria J.   +3 more
core   +1 more source

Androgen Receptor‐Induced Lactoferrin Accelerates Prostate Tumorigenesis Through Modulating Ferroptosis

Advanced Science, EarlyView.
This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu, Qiu Peng, Xiaoyue Zhang, Zhengshuo Li, Yangge Wu, Yuqing Wen, Run Zheng, Shuanglong Wu, Chenfei Zhou, Zhengyu Hu, Lanjun Shu, Xinyi Ma, Qiuyang Li, Ya Ma, Chunlin Ou, Ming Zhao, Songqing Fan, Lingyu Wei, Jian Ma   +18 more
wiley   +1 more source

Modulation of transforming growth factor beta2 (TGF-beta2) by inositol hexaphosphate in colon carcinogenesis in rats Modulação do fator transformador de crescimento beta2 (TGFbeta2) pelo inositol hexafosfato na carcinogênese colônica em ratos

Acta Cirúrgica Brasileira, 2006
PURPOSE: To evaluate modulation in the expression of Transforming growth factor beta2 (TGF-beta2) in short-term colon carcinogenesis. METHODS: 64 male rats was used, comprising 4 groups of 16 animals each: group 1 received Inositol hexaphosphate (IP6 ...
Guido Marks, Ricardo Dutra Aydos, Djalma José Fagundes, Elenir Rose Jardim Cury Pontes, Luiz Carlos Takita, Eva Glória Abrão Siufi do Amaral, Airton Rossini, Celso Massaschi Ynouye   +7 more
doaj   +1 more source

Social distancing cut down the prevalence of acute otitis media in children

Frontiers in Public Health, 2023
ObjectivesTo evaluate the additional, unintended benefits of social distancing in cutting down the prevalence of acute otitis media (AOM) in children, especially during coronavirus disease 2019 (COVID-19) periods.MethodsThe daily outpatient attendance of
Huiqian Yu, Dantong Gu, Fangzhou Yu, Qingzhong Li   +3 more
doaj   +1 more source

Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses

Advanced Science, EarlyView.
ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti, Giovanna Coceano, Mariline Mendes Silva, Jonatan Alvelid, Chiara Sgattoni, Andrea Volpato, Lea Rems, Luciano A. Masullo, Eduard M. Unterauer, Rafal Kowalewski, Lucie Delemotte, Erdinc Sezgin, Ralf Jungmann, Ilaria Testa   +13 more
wiley   +1 more source

Inhibition of gut microbial β-glucuronidase effectively prevents carcinogen-induced microbial dysbiosis and intestinal tumorigenesis

Pharmacological Research, 2022
The bidirectional interaction between carcinogens and gut microbiota that contributes to colorectal cancer is complicated. Reactivation of carcinogen metabolites by microbial β-glucuronidase (βG) in the gut potentially plays an important role in ...
Kai-Wen Cheng, Chih-Hua Tseng, I.-Ju Chen, Bo-Cheng Huang, Hui-Ju Liu, Kai-Wen Ho, Wen-Wei Lin, Chih-Hung Chuang, Ming-Yii Huang, Yu-Lin Leu, Steve R. Roffler, Jaw-Yuan Wang, Yeh-Long Chen, Tian-Lu Cheng   +13 more
doaj   +1 more source