Results 191 to 200 of about 98,173 (262)

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

Angiotensin II Induces Abdominal Aortic Branch Aneurysms in <i>Fibrillin-1</i> ^{<i>C1041G/+</i>} Mice-Brief Report. [PDF]

Arterioscler Thromb Vasc Biol
Franklin MK, Howatt DA, Moorleghen JJ, Sheppard MB, Katsumata Y, Sawada H, Lu HS, Daugherty A.   +7 more
europepmc   +1 more source

Case report: Endovascular treatment of a late aortic pseudoaneurysm due to gunshot injury. [PDF]

Radiol Case Rep
Statti JM, de la Reta ND, Oscos M, Pedroni P, Giachello F, Hauqui A, Scaglia J, Grinfeld D, Acevedo R, Sarmiento R, Solernó R.   +10 more
europepmc   +1 more source

Concurrent Use of Tasipimidine Oral Solution and Fluoxetine in Dogs

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT This exploratory randomized crossover study investigated pharmacokinetic interactions, functional alertness, and cardiovascular safety of tasipimidine oral solution administered alone and in combination with fluoxetine in healthy Beagle dogs (n = 8; 4 dogs per dose level), with a 7‐day washout between phases. Dogs received single oral doses of
Jenni Lindstedt, Jouko M. Levijoki, Johanna Tuunainen, Jens Häggström, Meri Ramela, Mira Korpivaara   +5 more
wiley   +1 more source

Successful open repair of blunt traumatic thoracoabdominal aortic injury with concomitant L1/L2 fracture-dislocation. [PDF]

J Cardiothorac Surg
Kanazawa Y, Yoshitake A, Takaki S, Gatate Y, Kinoshita O, Asakura T.   +5 more
europepmc   +1 more source

Premature closure underlies bias in medical diagnosis in students: A randomised controlled experiment

Medical Education, EarlyView.
Abstract Objective The purpose of the study reported in this article was to shed light on the cognitive mechanism mediating between biasing information and diagnostic error. The literature suggests at least two different hypotheses: premature closure leading biased participants to spend less time on diagnosis or increased competition between diagnostic
Awad Al Essa, Henk G. Schmidt, Silvia Mamede, Karla Knežević, Laura Zwaan, Mohi Magzoub   +5 more
wiley   +1 more source

Protocol for heterotopic mouse intestinal transplantation to study transplant immunology. [PDF]

STAR Protoc
Matsushima H, Soyama A, Hashimoto K, Morita-Nakagawa M, Datta S, Fujiki M, Abu-Elmagd K, Fujita T, Askeyev B, Miyamoto D, Hamada T, Adachi T, Eguchi S.   +12 more
europepmc   +1 more source

Porphyromonas gingivalis GroEL accelerates abdominal aortic aneurysm formation by matrix metalloproteinase‐2 SUMOylation in vascular smooth muscle cells: A novel finding for the activation of MMP‐2

Molecular Oral Microbiology, EarlyView.
Abstract Infection is a known cause of abdominal aortic aneurysm (AAA), and matrix metalloproteases‐2 (MMP‐2) secreted by vascular smooth muscle cells (SMCs) plays a key role in the structural disruption of the middle layer of the arteries during AAA progression.
Yi‐Wen Lin, Feng‐Yen Lin, Ze‐Hao Lai, Chien‐Sung Tsai, Yi‐Ting Tsai, Yen‐Sung Huang, Chen‐Wei Liu   +6 more
wiley   +1 more source

Sirtuin 1 Activation Mitigates Murine Vasculitis Severity by Promoting Mitophagy. [PDF]

Circ Res
Atici AE, Jena PK, Carvalho TT, Ross BL, Aubuchon EA, Lane ME, Gomez AC, Lee Y, Fishbein MC, Azer J, Mesquita T, Chen S, Crother TR, Arditi M, Noval Rivas M.   +14 more
europepmc   +1 more source

Internal Jugular Vein as an Alternative Access for Pacemaker Implantation: A Mostly Left IJ Case Series

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background Leadless pacemakers traditionally rely on femoral venous access, which may be limited in patients with unfavorable IVC anatomy, prior interventions, or situations where preserving femoral access is preferred. Internal jugular (IJ) access offers an alternative route, but real‐world data on IJ implantation of single‐ and dual‐chamber ...
Maya Asami Takagi, William Leon, Colin Mackenzie, Daniel Cortez   +3 more
wiley   +1 more source