Results 91 to 100 of about 745,128 (377)

Novel aspects of the pathogenesis of aneurysms of the abdominal aorta in humans

Cardiovascular Research, 2010
Aneurysm of the abdominal aorta (AAA) is a particular, specifically localized form of atherothrombosis, providing a unique human model of this disease.
J. Michel, J. Martín-Ventura, J. Egido, N. Sakalihasan, V. Treska, J. Lindholt, É. Allaire, U. Thorsteinsdóttir, G. Cockerill, J. Swedenborg   +9 more
semanticscholar   +1 more source

Computational simulations demonstrate altered wall shear stress in aortic coarctation patients previously treated by resection with end-to-end anastomosis [PDF]

, 2011
Background.  Atherosclerotic plaque in the descending thoracic aorta (dAo) is related to altered wall shear stress (WSS) for normal patients. Resection with end-to-end anastomosis (RWEA) is the gold standard for coarctation of the aorta (CoA) repair, but
Cava, Joseph Richard, Chan, Frandics P, Dholakia, Ronak Jashwant, Feinstein, Jeffrey A., Figueroa, Alberto, LaDisa, John F., Samyn, Margaret M, Taylor, Charles A., Vignon-Clementel, Irene E   +8 more
core   +1 more source

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

Advanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong, Weinan Guo, Yuxuan Qian, Wenyan Jin, Xiaozhen Li, Jingyuan Yang, Qingrong Ni, Shuang Wu, Fanni Li, Hua Wang, Chunying Li, Hong Cai   +11 more
wiley   +1 more source

Aorto‑esophageal Fistula following Botox Injection

Journal of the Belgian Society of Radiology
Aorto‑esophageal fistulas (AEF) are rare, often fatal connections between the thoracic aorta and esophagus, arising from aortic disease, esophageal conditions, or iatrogenic causes.
Thomas Saliba, Denis Tack
doaj   +1 more source

Impaired Collagen Biosynthesis and Cross‐linking in Aorta of Patients With Bicuspid Aortic Valve

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2013
Background Patients with bicuspid aortic valve (BAV) have an increased risk of developing ascending aortic aneurysm. In the present study, collagen homeostasis in nondilated and dilated aorta segments from patients with BAV was studied, with normal and ...
D. Wågsäter, V. Paloschi, R. Hanemaaijer, K. Hultenby, R. Bank, A. Franco-Cereceda, J. Lindeman, P. Eriksson   +7 more
semanticscholar   +1 more source

The non-obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine [PDF]

, 2008
The concept of Endothelium Derived Relaxing Factor (EDRF), put forward by Furchgott in the earlier 80s of the past century, implies that nitric oxide (NO) produced by NO synthase (NOS) in the endothelium in response to acetylcholine (ACh) passively ...
Frantisek Kristek, Igor Buchwalow, Joachim Neumann, Sona Cacanyiova, Vera Samoilova, Werner Boecker   +5 more
core   +1 more source

Skeletal Myogenic Progenitors Originating from Embryonic Dorsal Aorta Coexpress Endothelial and Myogenic Markers and Contribute to Postnatal Muscle Growth and Regeneration [PDF]

, 1999
Skeletal muscle in vertebrates is derived from somites, epithelial structures of the paraxial mesoderm, yet many unrelated reports describe the occasional appearance of myogenic cells from tissues of nonsomite origin, suggesting either ...
Berghella, Libera, Coletta, Marcello, Cossu, Giulio, Cusella-De Angelis, M. Gabriella, De Angelis, Luciana, Lattanzi, Laura, Ponzetto, Carola, Zanchi, Malvina   +7 more
core   +2 more sources

Targeting Adipose Tissue Function Protects Against Heart Failure with Preserved Ejection Fraction

Advanced Science, EarlyView.
This study explores the role adipose tissue (AT) phenotypes have in determining cardiovascular outcomes in an obesity‐related heart failure with preserved ejection fraction (HFpEF) model. Pharmacological induction of thermogenesis promoted resilience to HFpEF‐induced remodeling of AT and conferred cardioprotection. Surgical and genetic models confirmed
Jordan Jousma, Zhenbo Han, Jooman Park, Gege Yan, Sen Zhang, Youjeong Kwon, Sarath Babu Nukala, Jindpreet Kandola, Sandra Pinho, Chong Wee Liew, Yuwei Jiang, Sang‐Ging Ong   +11 more
wiley   +1 more source

Next-Generation Frozen Elephant Trunk Technique in the Era of Precision Medicine

Journal of Chest Surgery
The frozen elephant trunk (FET) technique can be applied to extensive aortic pathology, including lesions in the aortic arch and proximal descending thoracic aorta. FET is useful for tear-oriented surgery in dissections, managing malperfusion syndrome,
Suk-Won Song, Ha Lee, Myeong Su Kim, Randolph Hung Leung Wong, Jacky Yan Kit Ho, Wilson Y. Szeto, Heinz Jakob   +6 more
doaj   +1 more source

Umbral crítico de administración en pacientes con trauma severo y reanimación endovascular: ¿Un concepto útil?

Revista Colombiana de Cirugía
Introducción. Se describe la utilidad del umbral crítico de administración (CAT por su denominación en inglés) como herramienta para la reanimación hemostática en pacientes con trauma severo y oclusión endovascular aórtica. Métodos.
Natalia Padilla, Yaset Caicedo, José Julián Serna, Fernando Fernando Rodríguez-Holguín, Alexander Salcedo, Fredy Ariza, Daniela Burbano, Philip Leib, Alberto García, Carlos A. Ordoñez   +9 more
doaj   +1 more source