Results 91 to 100 of about 373,263 (301)

Phase Separation of TRIM21 Modulates PTPN14 Stability to Drive Flow‐Dependent Endothelial Activation and Atherogenesis

Advanced Science, EarlyView.
Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He, Qiannan Ma, Xue Wang, Jiaxu Mang, Chufeng Li, Bingjun Wu, Liu Yao, Yequn Chen, Qiankun Bao, Yi Zhu, Jinlong He   +10 more
wiley   +1 more source

Next-Generation Frozen Elephant Trunk Technique in the Era of Precision Medicine

Journal of Chest Surgery
The frozen elephant trunk (FET) technique can be applied to extensive aortic pathology, including lesions in the aortic arch and proximal descending thoracic aorta. FET is useful for tear-oriented surgery in dissections, managing malperfusion syndrome,
Suk-Won Song, Ha Lee, Myeong Su Kim, Randolph Hung Leung Wong, Jacky Yan Kit Ho, Wilson Y. Szeto, Heinz Jakob   +6 more
doaj   +1 more source

Pediatric Mycotic Pseudoaneurysm of the Ascending Aorta: A Case Report

, 2023
Jia-Guang Song,1,2,* Zi-Xin Yang,2,* Na Shi,3 Mei Zhu2 1Department of Ultrasound, Shandong Provincial Hospital, Shandong University, Jinan, 250021, People’s Republic of China; 2Department of Ultrasound, Shandong Provincial Hospital Affiliated to ...
Shi N, Zhu M, Yang ZX, Song JG
core  

Serial Molecular‐Microstructural Multimodal Intravascular Imaging of Atherosclerotic Plaques in Mice

Advanced Science, EarlyView.
A novel longitudinal molecular and microstructural intravascular imaging approach is developed to study murine atherosclerosis. The technique combines a unique surgical model with a miniaturized multimodal device to detect macrophage activity and lipid simultaneously.
Jiawen Li, Joanne T. M. Tan, Lei Xiang, Jiandi Liu, Ayla Hoogendoorn, Victoria A. Nankivell, Lauren Sandeman, Richard Le, Rouyan Chen, Robert A. McLaughlin, Peter J. Psaltis, Johan W. Verjans, Christina A. Bursill   +12 more
wiley   +1 more source

Open repair of long-segment aortic atresia complicated by uncontrolled hypertensionCentral Message

JTCVS Techniques, 2023
Matthew A. Thompson, BS, BA, Meghana Iyer, BS, Eric E. Roselli, MD   +2 more
doaj   +1 more source

Re-Do Endovascular Endoleak Embolization by Transprosthetic Puncture After Endovascular Aneurysm Repair

JACC: Case Reports
Background: Compared with open repair of abdominal aortic aneurysms, endovascular aneurysm repair (EVAR) is less invasive and results in better perioperative outcomes and lower perioperative mortality risk.
Livio D’Angelo, MD, Ioannis Skalidis, MD, PhD, Thierry Unterseeh, MD, Bastien Regrelle, MD, Raphael Philippart, MD, Benjamin Honton, MD, Antoine Sauguet, MD   +6 more
doaj   +1 more source

Histological Study Of Many Branches Of Aorta In Local Dog

Kufa Journal for Veterinary Medical Sciences, 2017
The aorta is the main artery in the body, originating from the left ventricle of the heart and extending down to the abdomen ,the study aimed  to classify the regions and the main branches of the aorta anatomically and histologically by several technique
Fatima hasab, Fawzi Al-Asadi
doaj   +1 more source

KLF5 Downregulation Links Impaired BNIP3‐Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease

Advanced Science, EarlyView.
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian, Jia‐Xi Gu, Zhang Yue, Chun‐Ze Yuan, Hai‐Bin Ji, Ao Li, Yu Zhong, Xiu‐Fan Xu, Yu‐Qiu He, Ye‐Fan Jiang, Hong‐Shan Chen, Xiang Chen, Meng‐Lin Chao, Yong‐Feng Shao   +13 more
wiley   +1 more source

Impact of aortic morphology on VA-ECMO performance: a combined statistical shape modeling and CFD approach

Frontiers in Bioengineering and Biotechnology
IntroductionThe veno-arterial extracorporeal membrane oxygenation (VA ECMO) system is a temporary support procedure to provide oxygenated blood in patients with cardiac or respiratory failure.
Marilena Mazzoli, Marilena Mazzoli, Emanuele Gasparotti, Emanuele Vignali, Dorela Haxhiademi, Simona Celi   +5 more
doaj   +1 more source

Coarctation of Aorta Masquerading as a Spinal Arteriovenous Malformation: A Case Report [PDF]

Coarctation of the aorta is a congenital disease involving the cardiovascular system. It has a varied presentation and is often under-diagnosed in clinical practice.
Ajith Varrior, Meet Waghela, Padma Vikram Badhe, Chandranshu Nagwekar   +3 more
core   +1 more source