Results 31 to 40 of about 373,263 (301)

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Interdisciplinarity and Patient Engagement: New Representations of Cardiovascular Anatomy

Reviews in Cardiovascular Medicine, 2022
Background: This article presents and discusses the genesis, making and public presentation of two artworks by British artist Sofie Layton, namely Blueprints and The Bud, which explore the anatomy of the heart infusing it with experiential and narrative ...
Giovanni Biglino, Sofie Layton, Alastair Hamer, Elena Giulia Milano, Massimo Caputo, Jo Wray   +5 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Open, hybrid, and endovascular repair of recoarctation, aneurysm, and pseudoaneurysm after aortic coarctation repairCentral MessagePerspective

JTCVS Techniques
Objective: After aortic coarctation repair, patients may develop peri-anastomotic aneurysms or recoarctation requiring reintervention. We describe the spectrum of late coarctation repair–associated complications, repair strategies, and outcomes. Methods:
Jonathan P. Putnam, BS, Matthew A. Thompson, MD, William C. Frankel, MD, Patrick R. Vargo, MD, Joanna Ghobrial, MD, Patcharapong Suntharos, MD, Margaret Fuchs, MD, Sean P. Lyden, MD, Francis J. Caputo, MD, Vidyasagar Kalahasti, MD, Ashley M. Lowry, MS, Eugene H. Blackstone, MD, Lars G. Svensson, MD, PhD, Eric E. Roselli, MD   +13 more
doaj   +1 more source

Rare association between giant-cell aortitis and giant-cell aortic valvulitis

Autopsy and Case Reports, 2023
Giant cell arteritis (GCA) is a type of chronic vasculitis that affects medium and large-caliber arteries, frequently related to aortic involvement and, consequently, to aneurysm formation. However, associated valvulitis with giant cells is uncommon. We
Georgina del Cisne Jadán Luzuriaga, Ricardo Ribeiro Dias, José Augusto Duncan Santiago, Vagner Madrini Junior, Walther Yoshiharu Ishikawa, Fabio Fernandes, Vera Demarchi Aiello   +6 more
doaj  

Asymptomatic unruptured aneurysm of the left sinus of Valsalva: a case history report

Российский кардиологический журнал, 2020
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G. K. Sadykova, D. O. Ivanov, A. S. Lepekhina, V. V. Ryazanov   +3 more
doaj   +1 more source

Increased Disarray of Extracellular Matrix Collagen-I Fiber Network and Compromised Biomechanics in Aortae From Marfan-Syndrome Mice Assessed Through Combined Opto-Biomechatronics. [PDF]

Adv Sci (Weinh)
Combined structure‐function assessment in aortic rings from Marfan mice using MechaMorph Opto‐Biomechatronics technology relates increased elasticity (stiffness) and dynamic viscosity and less ordered extracellular matrix 3D‐structure (collagen) as potential causes for impaired Windkessel function and compromised haemodynamics in Marfan's syndrome ...
Schneidereit D, Nagel A, Zwaans VIT, Schurr L, Ahr J, Haug M, Piluso A, Sporkova A, Karck M, Wagner AH, Friedrich O.   +10 more
europepmc   +2 more sources

Surgical treatment of aortic coarctation [PDF]

, 2004
Coarctation of the aorta accounts for about 8% of all congenital heart diseases. Since the first successful case of surgical treatment in 1944 by Crafoord and Nylin1 in Sweden, several surgical techniques have been employed in the treatment of this ...
Sagat, Michal, Nosal, Matej, Poruban, Rudolf, Omeje, Ikenna C., Hraska, Viktor   +4 more
core  

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Contemporary Utilization and Outcomes of Resuscitative Endovascular Balloon Occlusion of the Aorta for Traumatic Noncompressible Torso Hemorrhage in Korea: A Retrospective Multi-Center Study [PDF]

Journal of Acute Care Surgery
Purpose This study aimed to evaluate the utilization and outcomes of resuscitative endovascular balloon occlusion of the aorta (REBOA) in managing noncompressible torso hemorrhage (NCTH) among trauma patients in Korea.
Yoonjung Heo, Sung Wook Chang, Byungchul Yu, Byung Hee Kang, Pil Young Jung, Kyounghwan Kim, Dong Hun Kim   +6 more
doaj   +1 more source