Results 41 to 50 of about 366,058 (299)

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Contemporary Utilization and Outcomes of Resuscitative Endovascular Balloon Occlusion of the Aorta for Traumatic Noncompressible Torso Hemorrhage in Korea: A Retrospective Multi-Center Study [PDF]

Journal of Acute Care Surgery
Purpose This study aimed to evaluate the utilization and outcomes of resuscitative endovascular balloon occlusion of the aorta (REBOA) in managing noncompressible torso hemorrhage (NCTH) among trauma patients in Korea.
Yoonjung Heo, Sung Wook Chang, Byungchul Yu, Byung Hee Kang, Pil Young Jung, Kyounghwan Kim, Dong Hun Kim   +6 more
doaj   +1 more source

Genetic Variation in LRP1 Associates with Stanford Type B Aortic Dissection Risk and Clinical Outcome

Journal of Cardiovascular Development and Disease, 2022
Genetic variation in LRP1 (low-density lipoprotein receptor-related protein 1) was reported to be associated with thoracic aortic dissections and aneurysms.
Philipp Erhart, Daniel Körfer, Caspar Grond-Ginsbach, Jia-Lu Qiao, Moritz S. Bischoff, Maja Hempel, Christian P. Schaaf, Armin Grau, Dittmar Böckler   +8 more
doaj   +1 more source

Surgical treatment of aortic coarctation [PDF]

, 2004
Coarctation of the aorta accounts for about 8% of all congenital heart diseases. Since the first successful case of surgical treatment in 1944 by Crafoord and Nylin1 in Sweden, several surgical techniques have been employed in the treatment of this ...
Sagat, Michal, Nosal, Matej, Poruban, Rudolf, Omeje, Ikenna C., Hraska, Viktor   +4 more
core  

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Sheep femoral artery occlusion is well tolerated and does not result in ischemia

Animal Models and Experimental Medicine
Objective Sheep are commonly used as large animal pre‐clinical models for investigating cardiovascular therapies, interventions, anatomy and physiology.
Timothy Shiraev, Ziyu Wang, Lakshay Seth, Lisa Partel, Innes K. Wise, Hugh Paterson, John O'Sullivan, Sean Lal, Anthony S. Weiss, Paul Bannon, Robert D. Hume   +10 more
doaj   +1 more source

Optimizing treatment of proximal thoracic aortic graft infectionsCentral MessagePerspective

JTCVS Open
Objectives: To describe treatment, assess outcomes, and identify risk factors for primary infection, reinfection, and death in patients with proximal thoracic aortic graft infection.
Matthew A. Thompson, MD, Toshiki Fujiyoshi, MD, PhD, Benjamin Kramer, DO, PhD, Ashley M. Lowry, MS, MEd, Haytham Elgharably, MD, Steven Gordon, MD, Vidyasagar Kalahasti, MD, Nabin Shrestha, MD, Patrick Vargo, MD, Eugene H. Blackstone, MD, Eric E. Roselli, MD   +10 more
doaj   +1 more source

Anomalous right pulmonary artery from the aorta [PDF]

, 2006
Anomalous origin of the right pulmonary artery is a rare form of congenital heart disease. It usually presents in early infancy with heart failure and rapid development of pulmonary hypertension. There are about 131 cases reported in the literature and
Wong, Abdul Rahim, Rasool, Aida Hanum Ghulam, Mokhtar, S.A.I.   +2 more
core  

Mechanistic insights on age-related changes in heart-aorta-brain hemodynamic coupling using a pulse wave model of the entire circulatory system

, 2023
Raw data corresponding to the manuscript titled : Mechanistic insights on age-related changes in heart-aorta-brain hemodynamic coupling using a pulse wave model of the entire circulatory ...
Niema Pahlevan (10811518), Sohrab P. Mazandarani (8693223), Arian Aghilinejad (10811226), Faisal Amlani (10811507), Kevin King (70030)   +4 more
core   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source