Results 11 to 20 of about 178,494 (355)

Targeting interleukin-1β protects from aortic aneurysms induced by disrupted transforming growth factor β signaling [PDF]

, 2017
Aortic aneurysms are life-threatening conditions with effective treatments mainly limited to emergency surgery or trans-arterial endovascular stent grafts, thus calling for the identification of specific molecular targets.
Bizzotto, Dario, Braghetta, Paola, Bressan, Giorgio M., Carnevale, Daniela, Carnevale, Lorenzo, Carnevale, Raimondo, Casaburo, Manuel, Cifelli, Giuseppe, DA ROS, Francesco, Fardella, Stefania, Iacobucci, Roberta, Lembo, Giuseppe, Perrotta, Marialuisa, Vinciguerra, Iolanda   +13 more
core   +1 more source

TGFβ (transforming growth factor-β) blockade induces a human-like disease in a nondissecting mouse model of abdominal aortic aneurysm [PDF]

, 2017
Objective-Current experimental models of abdominal aortic aneurysm (AAA) do not accurately reproduce the major features of human AAA. We hypothesized that blockade of TGF beta (transforming growth factor-beta) activity-a guardian of vascular integrity ...
Clément, Marc, Esposito, Bruno, Finigan, Alison, Lareyre, Fabien, Mallat, Ziad, Master, Leanne, Patel, Meghana, Pohlod, Stefanie, Raffort, Juliette, Stergiopulos, Nikolaos, Taleb, Soraya, Trachet, Bram, Vandestienne, Marie   +12 more
core   +2 more sources

Different anti-contractile function and nitric oxide production of thoracic and abdominal perivascular adipose tissues

Frontiers in Physiology, 2016
Divergent phenotypes between the perivascular adipose tissue (PVAT) surrounding the abdominal and the thoracic aorta might be implicated in regional aortic differences, such as susceptibility to atherosclerosis.
Jamaira Aparecida Victorio, Milene Tavares Fontes, Luciana Venturini Rossoni, Ana Paula Davel   +3 more
doaj   +1 more source

Dissecção espontânea da aorta abdominal infrarrenal Spontaneous dissection of the infrarenal aorta

Jornal Vascular Brasileiro, 2012
A rotura da camada íntima que marca o início da dissecção aórtica se origina na maioria dos casos na aorta torácica, sendo rara a dissecção espontânea da aorta abdominal infra-renal. As três principais causas são: iatrogênica, traumática ou espontânea. A
Otacílio de Camargo Junior, Antonio Cláudio Guedes Chrispim, Claudio Roberto Cabrini Simões, Márcia Fayad Marcondes, Guilherme Camargo Gonçalves de Abreu, Guilherme Vieira Meirelles, Kelly Cristina de Moraes, Marcio Villar de Freitas, Marivan Pedra Araújo, Gustavo Braga Murta   +9 more
doaj   +1 more source

Remodeling of Aortic Configuration and Abdominal Aortic Branch Perfusion After Endovascular Repair of Acute Type B Aortic Dissection: A Computed Tomographic Angiography Follow-Up

Frontiers in Cardiovascular Medicine, 2021
Background: Thoracic endovascular aortic repair (TEVAR) for type B aortic dissection (TBAD) induces false lumen (FL) thrombosis, promotes favorable aortic remodeling, and makes an impact on abdominal aortic branch perfusion patterns.
Zihui Yuan, Yiqing Li, Bi Jin, Jian Wang
doaj   +1 more source

Concomitance of atherosclerotic lesions in arteries of the lower extremities and carotid arteries in patients with abdominal aorta aneurysm

Artery Research, 2016
Atherosclerosis was considered the main cause of abdominal aorta aneurysms. Many researchers suggest the presence of the association between these two entities.
Piotr Kaźmierski, Michał Pająk, Katarzyna Bogusiak   +2 more
doaj   +1 more source

Long term outcomes in men screened for abdominal aortic aneurysm : prospective cohort study [PDF]

, 2012
PMID: 22563092 [PubMed - indexed for MEDLINE] PMCID: PMC3344734 Free PMC ArticlePeer reviewedPublisher ...
Duncan, John L, Godden, David J, Harrild, Kirsten A, Iversen, Lisa, Lee, Amanda J   +4 more
core   +2 more sources

INFLUENCE OF THE WALLS ELASTICITY ON THE FLOW STRUCTURE OF THE THREE-DIMENSIONAL MODEL ON THE ABDOMINAL AORTA BIFURCATION WITH ILIAC ARTERIES

St. Petersburg Polytechnical University Journal: Physics and Mathematics, 2020
For the first time, a numerical study of the effect of vascular elasticity on blood flow was carried out in a model of the abdominal aorta bifurcation with iliac arteries of average statistical geometry.
Kotmakova Anna, Gataulin Yakov, Yukhnev Andrey, Zaitsev Dmitri   +3 more
doaj   +1 more source

Longitudinal imaging of murine atherosclerosis with 2-deoxy-2-[18F]fluoro-D-glucose and [18F]-sodium fluoride in genetically modified Apolipoprotein E knock-out and wild type mice

Scientific Reports, 2023
In a longitudinal design, four arterial segments in mice were followed by positron emission tomography/computed tomography (PET/CT) imaging. We aimed to determine how the tracers reflected the development of atherosclerosis via the uptake of 2-deoxy-2 ...
Harshvardhan A. Khare, Tina Binderup, Anne Mette Fisker Hag, Andreas Kjaer   +3 more
doaj   +1 more source

Site-Specific Effects of PECAM-1 on Atherosclerosis in LDL Receptor-Deficient Mice [PDF]

, 2008
Objective—Atherosclerosis is a vascular disease that involves lesion formation at sites of disturbed flow under the influence of genetic and environmental factors.
Arora, Shikha, Boylan, Brian, Fleming, Barbara, Fleming, Rose Ann, Goel, Reema, Mirura, Hiroto, Molthen, Robert C., Newman, Debra K., Newman, Peter J., Schrank, Benjamin R.   +9 more
core   +2 more sources