Results 91 to 100 of about 742,427 (349)

Immune Modulation as a Treatment for Abdominal Aortic Aneurysms [PDF]

open access: yes, 2018
In the United States, over 200,000 new patients are diagnosed with abdominal aortic aneurysm (AAA) each year. Consequently, over 40,000 highly morbid aortic reconstructions are performed each year to prevent aneurysm rupture, a catastrophic event ...
Murphy, Michael P., Wang, S. Keisin
core   +1 more source

Medial Hypoxia and Adventitial Vasa Vasorum Remodeling in Human Ascending Aortic Aneurysm

open access: yesFrontiers in Cardiovascular Medicine, 2018
Human ascending aortic aneurysms characteristically exhibit cystic medial degeneration of the aortic wall encompassing elastin degeneration, proteoglycan accumulation and smooth muscle cell loss. Most studies have focused on the aortic media and there is
M. Billaud   +4 more
semanticscholar   +1 more source

Ultrafine Molybdenum Wire Braided Neurointerventional Implants: Bridging Biodegradability and Neurovascular Safety for Stroke Treatment

open access: yesAdvanced Science, EarlyView.
Molybdenum (Mo), with its unique strength, uniform corrosion, and radiopacity, enables innovative biodegradable implants for transformative stroke therapy. Abstract Neurovascular implants for stroke intervention face a critical dilemma: permanent devices (e.g., nitinol stents, platinum coils) often trigger chronic inflammation and recurrence, whereas ...
Yunong Shen   +11 more
wiley   +1 more source

Role of Thrombospondin-1 in Mechanotransduction and Development of Thoracic Aortic Aneurysm in Mouse and Humans

open access: yesCirculation Research, 2018
Rationale: Abnormal mechanosensing of smooth muscle cells (SMCs) resulting from the defective elastin-contractile units has been suggested to drive the formation of thoracic aortic aneurysms; however, the precise molecular mechanism has not been ...
Yoshito Yamashiro   +13 more
semanticscholar   +1 more source

Ythdc1‐p300‐Klf5 Complex‐Mediated Golgi Dysfunction Promotes Aortic Aneurysm

open access: yesAdvanced Science, EarlyView.
In their Research Article (DOI: https://doi.org/10.1002/advs.202512116* lF: 14.1 Q1), Wenli Wang and co‐workers identifies a novel lncRNA m6A modification‐dependent regulatory mechanism of vascular homeostasis, and constructs a predictive model for post‐operative short‐term death based on AD patient's features, providing a platform to be able to ...
Wen‐Li Wang   +22 more
wiley   +1 more source

Propagation-based phase-contrast synchrotron imaging of aortic dissection in mice : from individual elastic lamella to 3D analysis [PDF]

open access: yes, 2018
In order to show the advantage and potential of propagation-based phase-contrast synchrotron imaging in vascular pathology research, we analyzed aortic medial ruptures in BAPN/AngII-infused mice, a mouse model for aortic dissection. Ascending and thoraco-
Aoki, Hiroki   +8 more
core   +3 more sources

Thoracic Aortic Aneurysm Growth: Role of Sex and Aneurysm Etiology

open access: yesJournal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2017
Background Thoracic aortic aneurysm (TAA) outcomes are worse in women than men, although reasons for sex differences are unknown. Because faster TAA growth is a risk factor for acute aortic syndromes, we sought to determine the role of sex and aneurysm ...
K. Cheung   +5 more
semanticscholar   +1 more source

Targeted 2‐Deoxy‐D‐Ribose Delivery by Biomimetic Nanoplatform Activates EGFR for Accelerated Heart Valve Endothelialization

open access: yesAdvanced Science, EarlyView.
This study develops a biomimetic nanoplatform using erythrocyte membrane‐camouflaged, CD144 antibody‐functionalized nanoparticles to deliver 2‐deoxy‐D‐ribose (2dDR). This system promotes heart valve endothelialization by enhancing endothelial cell migration and proliferation via EGFR activation, while improving hemocompatibility.
Xiang Qiu   +11 more
wiley   +1 more source

Surgery of infrarenal inflammatory aneurysm of abdominal aorta infected with methicillin resistant Staphylococcus aureus in a patient undergoing haemodialysis [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2008
INTRODUCTION Inflammatory abdominal aortic aneurysm accounts for 5% to 10% of all cases of abdominal aortic aneurysm and differs from typical atherosclerotic abdominal aortic aneurysm in many important ways. Although both inflammatory and atherosclerotic
Babić Srđan   +10 more
doaj   +1 more source

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