Results 91 to 100 of about 591,938 (222)
Unspliced XBP1 Confers VSMC Homeostasis and Prevents Aortic Aneurysm Formation via FoxO4 Interaction
Circulation Research, 2017 Rationale: Although not fully understood, the phenotypic transition of vascular smooth muscle cells exhibits at the early onset of the pathology of aortic aneurysms.
Guizhen Zhao +9 more
semanticscholar +1 more source
Assessment of Aortic Aneurysm Rupture Risk [PDF]
arXiv, 2011 The rupture of an abdominal aortic aneurysm (AAA) is associated with a high mortality. When an AAA ruptures, 50% of the patients die before reaching the hospital. Of the patients that are able to reach the operating room, only 50% have it successfully repaired (Fillinger et al, 2003).
arxiv
A Markov Decision Process Model to Guide Treatment of Abdominal Aortic Aneurysms [PDF]
, 2016 An abdominal aortic aneurysm (AAA) is an enlargement of the abdominal aorta which, if left untreated, can progressively widen and may rupture with fatal consequences. In this paper, we determine an optimal treatment policy using Markov decision process modeling.
arxiv +1 more source
Lineage-specific events underlie aortic root aneurysm pathogenesis in Loeys-Dietz syndrome
Journal of Clinical Investigation, 2019 The aortic root is the predominant site for development of aneurysm caused by heterozygous loss-of-function mutations in positive effectors of the transforming growth factor-&bgr; (TGF-&bgr;) pathway.
E. MacFarlane +13 more
semanticscholar +1 more source
Journal of Medical and Scientific Research, 2015 An aortic aneurysm (AA) is an increase in diameter of at least 50% greater than expected for the same aortic segment in unaffected individuals of the same age and sex. It may be asymptomatic except when ruptured or impending rupture.
Rajendra Kumar P +3 more
doaj +1 more source
Fluid dynamics of aortic root dilation in Marfan syndrome [PDF]
Journal of Biomechanics, 47, (2014) 3120-3128, 2014 Aortic root dilation and propensity to dissection are typical manifestations of the Marfan Syndrome (MS), a genetic defect leading to the degeneration of the elastic fibres. Dilation affects the structure of the flow and, in turn, altered flow may play a role in vessel dilation, generation of aneurysms, and dissection.
arxiv
Smad4 Deficiency in Smooth Muscle Cells Initiates the Formation of Aortic Aneurysm.
Circulation Research, 2016 RATIONALE Aortic aneurysm is a life-threatening cardiovascular disorder caused by the predisposition for dissection and rupture. Genetic studies have proved the involvement of the transforming growth factor-β (TGF-β) pathway in aortic aneurysm.
Peng Zhang +13 more
semanticscholar +1 more source
Multiple endovascular aortic aneurysm repair graft failures and re-interventions over 15 years
SAGE Open Medical Case Reports, 2015 Re-intervention on abdominal aortic aneurysm treated by endovascular aortic aneurysm repair for complications such as endoleak, graft migration, and graft failure is relatively common. However, re-do endovascular aortic aneurysm repair can be complex, as
Jessica Belchos +2 more
doaj +1 more source
BJS Open, 2019 Juxtarenal abdominal aortic aneurysms pose a significant challenge whether managed endovascularly or by open surgery. Fenestrated endovascular aneurysm repair (FEVAR) is now well established, but few studies have compared it with open surgical repair ...
A. D. Jones +5 more
semanticscholar +1 more source
3D convolutional neural network for abdominal aortic aneurysm segmentation [PDF]
arXiv, 2019 An abdominal aortic aneurysm (AAA) is a focal dilation of the aorta that, if not treated, tends to grow and may rupture. A significant unmet need in the assessment of AAA disease, for the diagnosis, prognosis and follow-up, is the determination of rupture risk, which is currently based on the manual measurement of the aneurysm diameter in a selected ...
arxiv