Results 101 to 110 of about 849,423 (411)

TRIM40 Drives Pathological Cardiac Hypertrophy and Heart Failure via Ubiquitination of PKN2

Advanced Science, EarlyView.
This study identifies the E3 ligase TRIM40 as a key driver of pathological cardiac hypertrophy. TRIM40 binds PKN2 via its B‐box domain and, through its C29‐dependent catalytic activity, mediates K63‐linked ubiquitination of PKN2. This modification enhances PKN2 phosphorylation at Ser815, thereby driving hypertrophy.
Risheng Zhao, Xiaoli Cui, Huizhu Du, Zhuoqun Wang, Chang Liu, Linxin Zhang, Jianing Qi, Di Yang, Hui Yu, Shuang Yan, Wei Liu, Haiming Sun, Mengyang Wang   +12 more
wiley   +1 more source

Corkscrew aortic arch in PHACES syndrome: Multimodal imaging of an unusual morphology of tortuous aortic arch in a rare but well-defined syndrome

Annals of Pediatric Cardiology, 2019
PHACES syndrome, a diffuse aortocraniocerebral vasculopathy, is a neural tube migration disorder, characterized by aortic coarctation and aberrant arch branches.
Ronak Sheth, Arvind Sahay Singh, Sreeja Pavithran, Kothandam Sivakumar   +3 more
doaj   +1 more source

Outcomes and re-interventions after one-stage repair of transposition of great arteries and aortic arch obstruction [PDF]

, 2017
Objectives: One-stage repair of transposition of great arteries (TGA) and aortic arch obstruction (AAO) is currently advocated, but carries formidable surgical challenges. This report presents our experience and re-interventions for residual lesions over
de Leval, Marc, Elliott, Martin, Huber, Christoph, Kostolny, Martin, Mimic, Branko, Oswal, Nilesh, Sullivan, Ian, Tsang, Victor   +7 more
core  

Npp1 promotes atherosclerosis in ApoE knockout mice. [PDF]

, 2011
Ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) generates inorganic pyrophosphate (PP(i)), a physiologic inhibitor of hydroxyapatite deposition.
Nitschke, Yvonne, Rutsch, Frank, Terkeltaub, Robert, Weissen-Plenz, Gabriele   +3 more
core   +1 more source

Simplifying aortic arch surgery: open zone 2 arch with single branched thoracic endovascular aortic repair completion.

Annals of Cardiothoracic Surgery, 2018
Background Distal aortic complications from acute DeBakey I dissection repair are an important source of late morbidity and mortality. We present an early experience of using a novel single-branched thoracic aortic endograft in conjunction with open ...
N. Desai, A. Hoedt, Grace J. Wang, W. Szeto, P. Vallabhajosyula, M. Reinke, J. Bavaria   +6 more
semanticscholar   +1 more source

A Soft‐Tip Hydraulically Steerable Catheter for Enhanced Flexibility and Safety in Vascular Interventions

Advanced Intelligent Systems, EarlyView.
This study introduces a hydraulically steerable catheter with a soft tip in vascular procedures. The steering soft tip achieves a minimal diameter of 2.6 mm and supports a 180° bend. Real‐time shape and position tracking, facilitated by segmentation and endpoint detection techniques, improves navigation.
Jingyi Kang, Ye Wang, Jiayuan Liu, Zhuhao Wang, Xuan Yang, Jie Wang, Jian Wu, Guochen Ning, Boyu Zhang, Hongen Liao   +9 more
wiley   +1 more source

An unusual variation of a right-sided aortic arch with a common subclavian trunk

Translational Research in Anatomy
Introduction: A right-sided aortic arch is a rare congenital cardiovascular anomaly that arises from persistence of the right fourth aortic arch and regression of the left fourth aortic arch.
Daryn Nguyen, Aditya Srinivasan, Natalia Lowry, Jeffrey Fahl, Michael P. Smith, Amanda S. Khan   +5 more
doaj   +1 more source

Non-invasive diagnosis of aortic arch anomalies in children – 15 years of own experience

Journal of Ultrasonography, 2019
Aim: To summarize our experience in echocardiographic diagnosis of aortic arch anomalies in pediatric patients. Materials and methods: A retrospective assessment of echocardiographic findings in Echo-Lab patients of the Pediatric Cardiac Surgery ...
Wojciech Mądry, Maciej Aleksander Karolczak, Marcin Myszkowski   +2 more
doaj   +1 more source

The ARCH Projects: design and rationale (IAASSG 001) [PDF]

, 2017
OBJECTIVE A number of factors limit the effectiveness of current aortic arch studies in assessing optimal neuroprotection strategies, including insufficient patient numbers, heterogenous definitions of clinical variables, multiple technical strategies ...
Bannon, Paul G., Bavaria, Joseph E., Beyersdorf, Friedhelm, Carrel, Thierry P., Chad Hughes, G., Chen, Edward P., Corvera, Joel S., Coselli, Joseph, Della Corte, Alessandro, Di Bartolomeo, Roberto, Di Eusanio, Marco, Ehrlich, Marek, Elefteriades, John A., Estrera, Anthony, Griepp, Randall B., Haverich, Axel, Hoffman, Andras, Jakob, Heinz, Kazui, Teruhisa, Kouchoukos, Nicholas T., LeMaire, Scott A., Matalanis, George, Misfeld, Martin, Mohr, Friedrich-Wilhelm, Numata, Satoshi, Okita, Yutaka, Oo, Aung, Patel, Himanshu J., Perreas, Konstantinos G., Pochettino, Alberto, Roselli, Eric E., Safi, Hazim J., Shrestha, Malakh, Sinatra, Riccardo, Sun, Li-Zhong, Sundt, Thoralf M., Tabata, Minoru, Tian, David H., Trimarchi, Santi, Underwood, Malcolm J., Wang, Chunsheng, Yan, Tristan D.   +41 more
core  

Reconstruction of the Aortic Arch in Neonates and Infants: The Importance of Patch Material [PDF]

, 2021
Ingrid M. van Beynum, Şerife Kurul, Thomas Krasemann, Michiel Dalinghaus, Pieter C. van de Woestijne, Jonathan R.G. Etnel, Ad J.J.C. Bogers   +6 more
openalex   +1 more source