Results 211 to 220 of about 726,988 (249)

Hemodynamics and Drinking in the Giraffe

open access: yesActa Physiologica, Volume 241, Issue 5, May 2025.
ABSTRACT Background The circulation of 4–6 m tall giraffes is markedly affected by gravity. To ensure cerebral perfusion, upright giraffes generate a blood pressure in excess of 200 mmHg. Before drinking, the head is lowered by 3–5 m, providing exceptional hemodynamic challenges.
Christian Aalkjær   +17 more
wiley   +1 more source

Mechanical Metamaterials for Bioengineering: In Vitro, Wearable, and Implantable Applications

open access: yesAdvanced Engineering Materials, Volume 27, Issue 7, April 2025.
Mechanical metamaterials with engineered architectures exhibit properties that differ from and greatly surpass those of their constituent bulk materials. This review summarizes the applications of mechanical metamaterials in bioengineering, focusing on advances in the last 5 years.
Madihah Kazim   +2 more
wiley   +1 more source

The Type III Secretion System (T3SS) of Escherichia Coli Promotes Atherosclerosis in Type 2 Diabetes Mellitus

open access: yesAdvanced Science, Volume 12, Issue 15, April 17, 2025.
Large‐scale studies indicate a strong relationship between the gut microbiome, type 2 diabetes mellitus (T2DM), and atherosclerotic cardiovascular disease (ASCVD). Here, a higher abundance of the type III secretion system (T3SS) virulence factors of Enterobacteriaceae/Escherichia‐Shigella in patients with T2DM‐related‐ASCVD, which correlates with their
Yao‐Yuan Zhang   +15 more
wiley   +1 more source

Disruption of the eEF1A1/ARID3A/PKC‐δ Complex by Neferine Inhibits Macrophage Glycolytic Reprogramming in Atherosclerosis

open access: yesAdvanced Science, Volume 12, Issue 15, April 17, 2025.
The eEF1A1/ARID3A/PKC‐δ complex critically regulates macrophage glycolytic reprogramming in atherosclerosis by mediating ARID3A phosphorylation and nuclear translocation, thereby driving ENO2 transcriptional activation. Neferine targets eEF1A1 to disrupt the eEF1A1/ARID3A/PKC‐δ complex to inhibit ENO2‐mediated macrophage glycolytic reprogramming in ...
Baoping Xie   +8 more
wiley   +1 more source

De Novo Balanced Translocations Disrupting the FBN1 Gene Diagnosed by Genome Sequencing: An Uncommon Cause of Marfan Syndrome Modifying Genetic Counseling

open access: yesAmerican Journal of Medical Genetics Part A, Volume 197, Issue 4, April 2025.
ABSTRACT Marfan syndrome (MFS) is a well‐characterized rare genetic connective tissue disorder. The features of MFS are primarily skeletal, ocular, and cardiovascular and are mainly caused by single‐nucleotide variants (SNVs) in the FBN1 gene (MIM#134797) located on chromosome 15q21.1.
C. Racine   +12 more
wiley   +1 more source

Physician Modified Endograft for Ruptured Dissecting Aortic Arch Aneurysm. [PDF]

open access: yesVasc Endovascular Surg
Solano A   +6 more
europepmc   +1 more source

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