Results 31 to 40 of about 68,079 (217)

Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses

Advanced Science, EarlyView.
ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti, Giovanna Coceano, Mariline Mendes Silva, Jonatan Alvelid, Chiara Sgattoni, Andrea Volpato, Lea Rems, Luciano A. Masullo, Eduard M. Unterauer, Rafal Kowalewski, Lucie Delemotte, Erdinc Sezgin, Ralf Jungmann, Ilaria Testa   +13 more
wiley   +1 more source

Persistent Fifth Aortic Arch Associated with 22q11.2 Deletion Syndrome

Journal of the Formosan Medical Association, 2006
Chromosome 22q11.2 deletion is frequently associated with conotruncal malformations and aortic arch anomalies. This study investigated the association of chromosome 22q11.2 deletion with clinical manifestations in four pediatric patients with persistent ...
Meng-Luen Lee
doaj   +1 more source

One-Stage Repair of Aortic Arch Hypoplasia Associated With Ventricular Septal Defect

Український журнал серцево-судинної хірургії, 2020
Background. Aortic arch hypoplasia is a congenital anomaly of the development of the aortic arch characterized by ground. Aortic arch hypoplasia is a congenital anomaly of the development of the aortic arch characterized by hemodynamically significant ...
Y. Truba, R. Sekelyk, I. Dzyurii, L. Prokopovych, O. Golovenko, V. Lazoryshynets   +5 more
doaj   +1 more source

CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction

Advanced Science, EarlyView.
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma, Jiali Jia, Juncong Lan, Jing Wang, Dan Rao, Lanlan Rao, Weibin Zhang, Dongpeng Wu, Jie Zhang, Gang Wang, Baohua Liu, Ying Ao, Zimei Wang   +12 more
wiley   +1 more source

Assessment of the quality of life comparison between open and endovascular aortic arch surgery: a pilot study

Journal of Cardiothoracic Surgery
Background Advancement in endovascular endografts have paved the way to the possibility of performing endovascular aortic arch repair in recent years. This has started to supersede the need for open aortic arch surgery.
Eric Thiam Aik Lim, Hannah S. Kim, Andrew McCombie, Andrew D. P. Laing, Adib Khanafer   +4 more
doaj   +1 more source

A case involving a bovine aortic arch contributing to blunt thoracic aortic injury of triple rupture close to the pericardial reflection

Trauma Case Reports
A blunt thoracic aortic injury is a fatal condition that often requires emergency surgery. Although injuries to the aortic isthmus are common in trauma patients, the proximal aortic arch often remains intact.
Takuma Aoki, Hidetoshi Oka, Naohiko Oki, Hirofumi Kasahara   +3 more
doaj   +1 more source

Senescent Cell Derived Artificial Vesicle‐Based Senolytic Sonovaccine Platform with Augmented Lymph Node Delivery and Antigen Cross‐Presentation Efficacy

Advanced Science, EarlyView.
A senolytic sonovaccine platform (SenoVac) is developed, in which senescent cell‐derived vesicles serve as broad senescent cell antigen reservior. The “2‐step” click chemistry strategy for effective lymph node delivery, and ultrasound‐triggered endosomal escape to boost cross‐presentation, ensures efficient senescent cell clearance and disease ...
Liang Zhang, Yubo Lai, Jia Wang, Lingling Liu, Jieyuan An, Mi Qu, Yuan Liang, Bijun Tan, Guodong Yang, Xuekang Yang, Lijun Yuan   +10 more
wiley   +1 more source

Endovascular treatment of a descending thoracic aorta aneurysm in a patient with right sided aortic arch: a case report

CVIR Endovascular
Backround Right-sided aortic arch is a rare congenital variant. The Edwards classification describes three types of right sided-aortic arch: right aortic arch with aberrant left subclavian artery, right aortic arch with mirror image branching, and right ...
Nefeli Ntinou, Panagiotis Petaloudis, Dimitra Tachmetzidi Papoutsi, Vasileios Panou, Myrto Papadopoulou, Dimitrios Tomais, Ioannis Kalogeropoulos, Theodoros Kratimenos   +7 more
doaj   +1 more source

Type III aortic arch angulation increases aortic stiffness: Analysis from an ex vivo porcine modelCentral MessagePerspective

JTCVS Open
Objective: The relationship among increased aortic arch angulation, aortic flow dynamics, and vessel wall stiffness remains unclear. This experimental ex vivo study investigated how increased aortic arch angulation affects aortic stiffness and stent ...
Tim J. Mandigers, MD, Ariel F. Pascaner, PhD, Michele Conti, PhD, Martina Schembri, MS, Sonja Jelic, BS, Alessandra Favilli, DVM, Daniele Bissacco, MD, Maurizio Domanin, MD, Joost A. van Herwaarden, MD, PhD, Ferdinando Auricchio, PhD, Santi Trimarchi, MD, PhD   +10 more
doaj   +1 more source

Surgical repair of a pseudocoarctation with cervical aortic arch complicated by multiple aneurysms of the aorta: a case report

The Pan African Medical Journal, 2017
Aortic pseudocoarctation is a rare congenital anomaly characterized by elongation and deformity of the aortic arch and is known to be associated with aneurysmal formation.
Said Makani, Julia Mitchell, Olivier Metton, Sylvie Di Filippo, Roland Henaine, Jean Ninet   +5 more
doaj   +1 more source