Results 41 to 50 of about 72,082 (267)

A case involving a bovine aortic arch contributing to blunt thoracic aortic injury of triple rupture close to the pericardial reflection

Trauma Case Reports
A blunt thoracic aortic injury is a fatal condition that often requires emergency surgery. Although injuries to the aortic isthmus are common in trauma patients, the proximal aortic arch often remains intact.
Takuma Aoki, Hidetoshi Oka, Naohiko Oki, Hirofumi Kasahara   +3 more
doaj   +1 more source

Phase Separation of TRIM21 Modulates PTPN14 Stability to Drive Flow‐Dependent Endothelial Activation and Atherogenesis

Advanced Science, EarlyView.
Disturbed flow promotes the formation of TRIM21‐rich biomolecular droplets, which concentrate TRIM21 and PTPN14 and facilitate their SPRY‐FERM interaction (illustrated by the TRIM21 D355‐PTPN14 R132 salt bridge). This condensate‐driven proximity enables TRIM21 to catalyze K48‐linked polyubiquitination of PTPN14 at lysine 956, leading to proteasome ...
Xue He, Qiannan Ma, Xue Wang, Jiaxu Mang, Chufeng Li, Bingjun Wu, Liu Yao, Yequn Chen, Qiankun Bao, Yi Zhu, Jinlong He   +10 more
wiley   +1 more source

Endovascular treatment of a descending thoracic aorta aneurysm in a patient with right sided aortic arch: a case report

CVIR Endovascular
Backround Right-sided aortic arch is a rare congenital variant. The Edwards classification describes three types of right sided-aortic arch: right aortic arch with aberrant left subclavian artery, right aortic arch with mirror image branching, and right ...
Nefeli Ntinou, Panagiotis Petaloudis, Dimitra Tachmetzidi Papoutsi, Vasileios Panou, Myrto Papadopoulou, Dimitrios Tomais, Ioannis Kalogeropoulos, Theodoros Kratimenos   +7 more
doaj   +1 more source

Type III aortic arch angulation increases aortic stiffness: Analysis from an ex vivo porcine modelCentral MessagePerspective

JTCVS Open
Objective: The relationship among increased aortic arch angulation, aortic flow dynamics, and vessel wall stiffness remains unclear. This experimental ex vivo study investigated how increased aortic arch angulation affects aortic stiffness and stent ...
Tim J. Mandigers, MD, Ariel F. Pascaner, PhD, Michele Conti, PhD, Martina Schembri, MS, Sonja Jelic, BS, Alessandra Favilli, DVM, Daniele Bissacco, MD, Maurizio Domanin, MD, Joost A. van Herwaarden, MD, PhD, Ferdinando Auricchio, PhD, Santi Trimarchi, MD, PhD   +10 more
doaj   +1 more source

Surgical repair of a pseudocoarctation with cervical aortic arch complicated by multiple aneurysms of the aorta: a case report

The Pan African Medical Journal, 2017
Aortic pseudocoarctation is a rare congenital anomaly characterized by elongation and deformity of the aortic arch and is known to be associated with aneurysmal formation.
Said Makani, Julia Mitchell, Olivier Metton, Sylvie Di Filippo, Roland Henaine, Jean Ninet   +5 more
doaj   +1 more source

One-Stage Repair of Aortic Arch Hypoplasia Associated With Ventricular Septal Defect

Український журнал серцево-судинної хірургії, 2020
Background. Aortic arch hypoplasia is a congenital anomaly of the development of the aortic arch characterized by ground. Aortic arch hypoplasia is a congenital anomaly of the development of the aortic arch characterized by hemodynamically significant ...
Y. Truba, R. Sekelyk, I. Dzyurii, L. Prokopovych, O. Golovenko, V. Lazoryshynets   +5 more
doaj   +1 more source

Serial Molecular‐Microstructural Multimodal Intravascular Imaging of Atherosclerotic Plaques in Mice

Advanced Science, EarlyView.
A novel longitudinal molecular and microstructural intravascular imaging approach is developed to study murine atherosclerosis. The technique combines a unique surgical model with a miniaturized multimodal device to detect macrophage activity and lipid simultaneously.
Jiawen Li, Joanne T. M. Tan, Lei Xiang, Jiandi Liu, Ayla Hoogendoorn, Victoria A. Nankivell, Lauren Sandeman, Richard Le, Rouyan Chen, Robert A. McLaughlin, Peter J. Psaltis, Johan W. Verjans, Christina A. Bursill   +12 more
wiley   +1 more source

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

Advanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang, Jieyu Cui, Chunlu Huang, Wanyi Guo, Tong Liu, Yi Zhu, Shuai Shao, Kangyin Chen, Jinlong He, Qiankun Bao   +9 more
wiley   +1 more source

Subclavian steal syndrome in a right aortic arch with aberrant left subclavian artery atresia

SAGE Open Medical Case Reports, 2023
Congenital aortic arch anomalies are an uncommon diagnosis resulting from embryologic malformations during the fourth to eighth week of gestation. Asymptomatic variants frequently are overlooked in the perinatal period and diagnosed incidentally during ...
Jonathan Nakata, Kurt R Stahlfeld, Samuel T Simone   +2 more
doaj   +1 more source

Increased Disarray of Extracellular Matrix Collagen‐I Fiber Network and Compromised Biomechanics in Aortae From Marfan‐Syndrome Mice Assessed Through Combined Opto‐Biomechatronics

Advanced Science, EarlyView.
Combined structure‐function assessment in aortic rings from Marfan mice using MechaMorph Opto‐Biomechatronics technology relates increased elasticity (stiffness) and dynamic viscosity and less ordered extracellular matrix 3D‐structure (collagen) as potential causes for impaired Windkessel function and compromised haemodynamics in Marfan's syndrome ...
Dominik Schneidereit, Anika Nagel, Vanessa I. T. Zwaans, Laureen Schurr, Jonas Ahr, Michael Haug, Anna Piluso, Alexandra Sporkova, Matthias Karck, Andreas H. Wagner, Oliver Friedrich   +10 more
wiley   +1 more source