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Calcific Aortic Stenosis

New England Journal of Medicine, 1962
THE transventricular and transaortic approaches, with visualization of the valve, to correct calcareous aortic stenosis were logical and progressive strides in the development of the surgical management of this disease.1 2 3 4 However, these procedures at best were limited to attempts to increase the size of the orifice by blind instrumental or digital
C A, HUFNAGEL, P W, CONRAD
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Models of Aortic Valve Calcification

Journal of Investigative Medicine, 2007
Aortic valve stenosis is a complex inflammatory process, akin to arterial atherosclerosis, involving lymphocytic infiltrates, macrophages, foam cells, endothelial activation and dysfunction, increased cellularity and extracellular matrix deposition, and lipoprotein accumulation.
Marie, Guerraty, Emile R, Mohler Iii
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The role of the matrix in aortic calcification

Archives of Biochemistry and Biophysics, 1964
Abstract The function of the aorta in aortic calcification in vitro has been investigated. In this system calcification does not depend on metabolic processes in the aorta but on the nucleating activity of elastin fibers. Homogenates of aorta calcify, but fractions isolated by centrifugation from the homogenate do not.
E, SCHIFFMANN   +2 more
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Pathology of Calcific Aortic Stenosis

Future Cardiology, 2011
With the aging of the general population in industrialized nations, calcific aortic stenosis (CAS) is becoming an increasingly important medical problem. The etiology is for the most part, dependent on the age at presentation; the two predominant causes in the western world are calcific aortic valve disease arising in a tricuspid aortic valve and ...
Elena, Ladich   +3 more
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Aortic calcification in urolithiasis patients

Scandinavian Journal of Urology and Nephrology, 2007
To examine the relationship between urolithiasis and calcification of the aortic artery.We examined the relationship between urolithiasis and calcification of the aortic artery in 181 patients with urinary calcium stones (stone group) and in 181 without a history of urolithiasis (control group).
Takahiro, Yasui   +5 more
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Calcific aortic stenosis: an update

Nature Clinical Practice Cardiovascular Medicine, 2007
Calcific aortic stenosis in the elderly is the number one cause of surgical valve replacement in the US and Europe. The incidence of calcific aortic stenosis is increasing as the general age of the population increases. For many years, rheumatic heart disease was the main cause of aortic valve disease.
Nalini M, Rajamannan   +2 more
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Mitral calcification in aortic stenosis

European Heart Journal, 1988
To appreciate the incidence, the promoting factors and the consequences of mitral calcification in aortic stenosis (AS), the data from 675 patients operated on for AS were reviewed. Mitral calcification was revealed by fluoroscopy, echocardiography and/or surgery. Mitral annular calcification (MAC) was observed in 169 patients (25%).
P L, Michel   +6 more
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Calcific Aortic Stenosis

JAMA
ImportanceCalcific aortic stenosis (AS) restricts the aortic valve opening during systole due to calcification and fibrosis of either a congenital bicuspid or a normal trileaflet aortic valve. In the US, AS affects 1% to 2% of adults older than 65 years and approximately 12% of adults older than 75 years. Worldwide, AS leads to more than 100 000 deaths
Catherine M, Otto   +2 more
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Translocation of aortic valve for calcific aortic stenosis

The Japanese Journal of Thoracic and Cardiovascular Surgery, 2000
A 56-year-old man underwent surgery for treatment of severe calcific aortic stenosis. Because it was found after excision of the aortic valve that calcification of the annulus was too extensive for the placement of sutures, translocation of the aortic valve was performed.
M, Ninomiya   +4 more
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